Biosynthesis of amino acids

Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Biosynthesis of amino acids Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Biosynthesis of amino acids pathway


KO Description #in this genome All occurrences
K00003 homoserine dehydrogenase [EC:1.1.1.3] 0 0
K00013 histidinol dehydrogenase [EC:1.1.1.23] 1 7
K00014 shikimate dehydrogenase [EC:1.1.1.25] 1 7
K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] 0 0
K00031 isocitrate dehydrogenase [EC:1.1.1.42] 1 7
K00052 3-isopropylmalate dehydrogenase [EC:1.1.1.85] 1 7
K00053 ketol-acid reductoisomerase [EC:1.1.1.86] 1 7
K00058 D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1 7
K00133 aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] 2 14
K00134 glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1 7
K00143 L-2-aminoadipate reductase [EC:1.2.1.95] 0 0
K00145 N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] 1 7
K00147 glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] 1 7
K00150 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] 0 0
K00211 prephenate dehydrogenase (NADP+) [EC:1.3.1.13] 0 0
K00215 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] 1 7
K00220 cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12] 0 0
K00264 glutamate synthase (NADH) [EC:1.4.1.14] 0 0
K00265 glutamate synthase (NADPH) large chain [EC:1.4.1.13] 1 2
K00266 glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1 13
K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] 1 7
K00290 saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7] 0 0
K00293 saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10] 0 0
K00500 phenylalanine-4-hydroxylase [EC:1.14.16.1] 0 0
K00548 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] 1 7
K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] 1 7
K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] 1 7
K00611 ornithine carbamoyltransferase [EC:2.1.3.3] 1 7
K00615 transketolase [EC:2.2.1.1] 1 7
K00616 transaldolase [EC:2.2.1.2] 1 7
K00618 amino-acid N-acetyltransferase [EC:2.3.1.1] 0 0
K00619 amino-acid N-acetyltransferase [EC:2.3.1.1] 0 0
K00620 glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 0 0
K00640 serine O-acetyltransferase [EC:2.3.1.30] 2 9
K00641 homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] 0 0
K00651 homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] 1 7
K00674 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] 1 7
K00765 ATP phosphoribosyltransferase [EC:2.4.2.17] 1 7
K00766 anthranilate phosphoribosyltransferase [EC:2.4.2.18] 0 6
K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] 1 7
K00800 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] 1 7
K00811 aspartate aminotransferase, chloroplastic [EC:2.6.1.1] 0 0
K00812 aspartate aminotransferase [EC:2.6.1.1] 0 0
K00813 aspartate aminotransferase [EC:2.6.1.1] 1 7
K00814 alanine transaminase [EC:2.6.1.2] 0 0
K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9] 1 13
K00818 acetylornithine aminotransferase [EC:2.6.1.11] 0 0
K00821 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1 7
K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] 1 7
K00831 phosphoserine aminotransferase [EC:2.6.1.52] 1 7
K00832 aromatic-amino-acid transaminase [EC:2.6.1.57] 1 7
K00836 diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] 0 0
K00838 aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5] 0 0
K00841 aminotransferase [EC:2.6.1.-] 0 0
K00850 6-phosphofructokinase 1 [EC:2.7.1.11] 1 6
K00872 homoserine kinase [EC:2.7.1.39] 1 7
K00873 pyruvate kinase [EC:2.7.1.40] 3 15
K00891 shikimate kinase [EC:2.7.1.71] 2 14
K00918 ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] 0 0
K00927 phosphoglycerate kinase [EC:2.7.2.3] 1 7
K00928 aspartate kinase [EC:2.7.2.4] 1 7
K00930 acetylglutamate kinase [EC:2.7.2.8] 1 6
K00931 glutamate 5-kinase [EC:2.7.2.11] 1 7
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1 7
K01079 phosphoserine phosphatase [EC:3.1.3.3] 1 7
K01089 imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] 1 7
K01243 adenosylhomocysteine nucleosidase [EC:3.2.2.9] 1 7
K01438 acetylornithine deacetylase [EC:3.5.1.16] 1 7
K01439 succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] 1 7
K01476 arginase [EC:3.5.3.1] 0 0
K01496 phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] 0 0
K01523 phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] 0 0
K01586 diaminopimelate decarboxylase [EC:4.1.1.20] 1 7
K01609 indole-3-glycerol phosphate synthase [EC:4.1.1.48] 0 0
K01620 threonine aldolase [EC:4.1.2.48] 1 7
K01622 fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] 0 0
K01623 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] 0 0
K01624 fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1 13
K01626 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] 4 23
K01647 citrate synthase [EC:2.3.3.1] 1 7
K01649 2-isopropylmalate synthase [EC:2.3.3.13] 1 7
K01652 acetolactate synthase I/II/III large subunit [EC:2.2.1.6] 2 20
K01653 acetolactate synthase I/III small subunit [EC:2.2.1.6] 1 13
K01655 homocitrate synthase [EC:2.3.3.14] 0 0
K01656 anthranilate synthase / indole-3-glycerol phosphate synthase [EC:4.1.3.27 4.1.1.48] 0 0
K01657 anthranilate synthase component I [EC:4.1.3.27] 1 7
K01658 anthranilate synthase component II [EC:4.1.3.27] 0 6
K01663 imidazole glycerol-phosphate synthase [EC:4.3.2.10] 0 0
K01681 aconitate hydratase [EC:4.2.1.3] 1 7
K01682 aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] 1 7
K01687 dihydroxy-acid dehydratase [EC:4.2.1.9] 1 7
K01689 enolase [EC:4.2.1.11] 1 7
K01693 imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] 0 0
K01694 tryptophan synthase [EC:4.2.1.20] 0 0
K01695 tryptophan synthase alpha chain [EC:4.2.1.20] 1 7
K01696 tryptophan synthase beta chain [EC:4.2.1.20] 1 7
K01697 cystathionine beta-synthase [EC:4.2.1.22] 0 0
K01702 3-isopropylmalate dehydratase [EC:4.2.1.33] 0 0
K01703 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] 1 7
K01704 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] 1 7
K01705 homoaconitate hydratase [EC:4.2.1.36] 0 0
K01713 cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91] 0 0
K01714 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] 2 8
K01733 threonine synthase [EC:4.2.3.1] 1 7
K01735 3-dehydroquinate synthase [EC:4.2.3.4] 1 7
K01736 chorismate synthase [EC:4.2.3.5] 1 7
K01738 cysteine synthase [EC:2.5.1.47] 1 7
K01739 cystathionine gamma-synthase [EC:2.5.1.48] 1 1
K01750 ornithine cyclodeaminase [EC:4.3.1.12] 0 0
K01752 L-serine dehydratase [EC:4.3.1.17] 2 14
K01754 threonine dehydratase [EC:4.3.1.19] 1 13
K01755 argininosuccinate lyase [EC:4.3.2.1] 1 7
K01758 cystathionine gamma-lyase [EC:4.4.1.1] 0 0
K01760 cysteine-S-conjugate beta-lyase [EC:4.4.1.13] 0 0
K01778 diaminopimelate epimerase [EC:5.1.1.7] 1 7
K01783 ribulose-phosphate 3-epimerase [EC:5.1.3.1] 1 7
K01803 triosephosphate isomerase (TIM) [EC:5.3.1.1] 1 7
K01807 ribose 5-phosphate isomerase A [EC:5.3.1.6] 1 7
K01808 ribose 5-phosphate isomerase B [EC:5.3.1.6] 0 0
K01814 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] 1 7
K01817 phosphoribosylanthranilate isomerase [EC:5.3.1.24] 0 4
K01834 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] 1 7
K01850 chorismate mutase [EC:5.4.99.5] 0 0
K01914 aspartate--ammonia ligase [EC:6.3.1.1] 1 7
K01915 glutamine synthetase [EC:6.3.1.2] 1 7
K01940 argininosuccinate synthase [EC:6.3.4.5] 1 7
K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16] 0 0
K01953 asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] 0 0
K01958 pyruvate carboxylase [EC:6.4.1.1] 0 0
K01959 pyruvate carboxylase subunit A [EC:6.4.1.1] 0 0
K01960 pyruvate carboxylase subunit B [EC:6.4.1.1] 0 0
K02203 phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] 0 0
K02204 homoserine kinase type II [EC:2.7.1.39] 0 0
K02500 imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] 1 7
K02501 imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] 1 7
K02502 ATP phosphoribosyltransferase regulatory subunit 0 0
K03340 diaminopimelate dehydrogenase [EC:1.4.1.16] 1 7
K03785 3-dehydroquinate dehydratase I [EC:4.2.1.10] 0 0
K03786 3-dehydroquinate dehydratase II [EC:4.2.1.10] 1 7
K03856 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] 0 0
K04092 chorismate mutase [EC:5.4.99.5] 0 0
K04093 chorismate mutase [EC:5.4.99.5] 0 0
K04486 histidinol-phosphatase (PHP family) [EC:3.1.3.15] 0 0
K04516 chorismate mutase [EC:5.4.99.5] 0 0
K04517 prephenate dehydrogenase [EC:1.3.1.12] 0 0
K04518 prephenate dehydratase [EC:4.2.1.51] 0 0
K05359 arogenate/prephenate dehydratase [EC:4.2.1.91 4.2.1.51] 0 0
K05602 histidinol-phosphatase [EC:3.1.3.15] 0 0
K05822 tetrahydrodipicolinate N-acetyltransferase [EC:2.3.1.89] 0 0
K05823 N-acetyldiaminopimelate deacetylase [EC:3.5.1.47] 0 0
K05824 homoisocitrate dehydrogenase [EC:1.1.1.87] 0 0
K05827 [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43] 0 0
K05828 [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19] 0 0
K05829 [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106] 0 0
K05830 [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] 0 0
K05831 [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132] 0 0
K05942 citrate (Re)-synthase [EC:2.3.3.3] 0 0
K06001 tryptophan synthase beta chain [EC:4.2.1.20] 0 0
K06208 chorismate mutase [EC:5.4.99.5] 0 0
K06209 chorismate mutase [EC:5.4.99.5] 0 0
K07173 S-ribosylhomocysteine lyase [EC:4.4.1.21] 1 7
K08093 3-hexulose-6-phosphate synthase [EC:4.1.2.43] 0 0
K08094 6-phospho-3-hexuloisomerase [EC:5.3.1.27] 0 0
K09011 (R)-citramalate synthase [EC:2.3.3.21] 0 0
K09065 N-acetylornithine carbamoyltransferase [EC:2.1.3.9] 0 0
K09758 aspartate 4-decarboxylase [EC:4.1.1.12] 0 0
K10150 cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22] 0 0
K10206 LL-diaminopimelate aminotransferase [EC:2.6.1.83] 0 0
K10977 methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] 0 0
K10978 methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] 0 0
K11067 N-acetylglutamate synthase [EC:2.3.1.1] 0 0
K11258 acetolactate synthase II small subunit [EC:2.2.1.6] 1 7
K11358 aspartate aminotransferase [EC:2.6.1.1] 0 0
K11389 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) [EC:1.2.7.6] 0 0
K11645 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] 1 7
K11755 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] 1 7
K12339 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] 1 7
K12406 pyruvate kinase isozymes R/L [EC:2.7.1.40] 0 0
K12524 bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] 1 7
K12525 bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3] 1 7
K12526 bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4] 0 0
K12657 delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41] 0 0
K12659 N-acetyl-gamma-glutamyl-phosphate reductase / acetylglutamate kinase [EC:1.2.1.38 2.7.2.8] 0 0
K13034 L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9] 0 0
K13497 anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18] 0 0
K13498 indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24] 1 7
K13501 anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24] 0 0
K13503 anthranilate synthase [EC:4.1.3.27] 0 0
K13810 transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 0 0
K13812 bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] 0 0
K13829 shikimate kinase / 3-dehydroquinate synthase [EC:2.7.1.71 4.2.3.4] 0 0
K13830 pentafunctional AROM polypeptide [EC:4.2.3.4 4.2.1.10 1.1.1.25 2.7.1.71 2.5.1.19] 0 0
K13831 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27] 0 0
K13832 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25] 0 0
K13853 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5] 0 0
K14152 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23] 0 0
K14155 cysteine-S-conjugate beta-lyase [EC:4.4.1.13] 1 13
K14170 chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51] 1 7
K14187 chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] 1 7
K14260 alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] 1 7
K14267 N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] 0 0
K14272 glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44] 0 0
K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] 0 0
K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] 0 0
K14677 aminoacylase [EC:3.5.1.14] 0 0
K14681 argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1] 0 0
K14682 amino-acid N-acetyltransferase [EC:2.3.1.1] 1 7
K15227 arogenate dehydrogenase (NADP+), plant [EC:1.3.1.78] 0 0
K15633 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 0 0
K15634 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] 1 7
K15635 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 0 0
K15849 bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [EC:2.6.1.1 2.6.1.78 2.6.1.79] 0 0
K16305 fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] 0 0
K16306 fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] 0 0
K16370 6-phosphofructokinase 2 [EC:2.7.1.11] 0 0
K16792 methanogen homoaconitase large subunit [EC:4.2.1.114] 0 0
K16793 methanogen homoaconitase small subunit [EC:4.2.1.114] 0 0
K17069 O-acetylhomoserine/O-acetylserine sulfhydrylase [EC:2.5.1.49 2.5.1.47] 0 0
K17216 cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134] 0 0
K17217 cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] 0 0
K17450 homoaconitase [EC:4.2.1.-] 0 0
K17462 putative AdoMet-dependent methyltransferase [EC:2.1.1.-] 0 0
K17753 isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286] 0 0
K17989 L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] 0 0
K18649 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15] 0 0
K19412 glutamate---[amino group carrier protein] ligase [EC:6.3.2.60] 0 0
K21071 ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 0 0
K22305 phosphoserine phosphatase [EC:3.1.3.3] 0 0
K22476 N-acetylglutamate synthase [EC:2.3.1.1] 0 0
K22477 N-acetylglutamate synthase [EC:2.3.1.1] 1 7
K22478 bifunctional N-acetylglutamate synthase/kinase [EC:2.3.1.1 2.7.2.8] 0 0
K22846 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] 0 0
K23304 serine O-acetyltransferase [EC:2.3.1.30] 0 0
K24017 phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24] 0 0
K24018 cyclohexadieny/prephenate dehydrogenase / 3-phosphoshikimate 1-carboxyvinyltransferase [EC:1.3.1.43 1.3.1.12 2.5.1.19] 0 0
K24034 spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10] 0 0
K24042 methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] 0 0
K25528 phosphoserine phosphatase [EC:3.1.3.3] 0 0