K00031


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00031
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00031
KO K00031
Description isocitrate dehydrogenase [EC:1.1.1.42]

KO part of 11 pathways

Citrate cycle (TCA cycle)
Glutathione metabolism
Other carbon fixation pathways
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Peroxisome
Central carbon metabolism in cancer

KO part of 4 modules

M00009 Central carbohydrate metabolism Citrate cycle (TCA cycle, Krebs cycle)
M00010 Central carbohydrate metabolism Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00173 Carbon fixation Reductive citrate cycle (Arnon-Buchanan cycle)
M00740 Other carbohydrate metabolism Methylaspartate cycle

Occurence in the database

K00031 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1974 FBDBKF_14545 3630 4883 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S1
1 group_1974 EHELCC_15350 33706 34959 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S2
2 group_1974 NLDBIP_15880 33706 34959 -1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S4
3 group_1974 LHKJJB_15960 81727 82980 1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S3
4 group_1974 HKOGLL_15080 80939 82192 1 icd NADP-dependent isocitrate dehydrogenase Morganella morganii S5
5 group_1974 F4V73_RS07340 1531909 1533162 -1 icd NADP-dependent isocitrate dehydrogenase Morganella psychrotolerans
6 group_1974 PMI_RS04380 982975 984228 1 icd NADP-dependent isocitrate dehydrogenase Proteus mirabilis HI4320