K00600


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00600, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00600
KO K00600
Description glycine hydroxymethyltransferase [EC:2.1.2.1]

KO part of 12 pathways

Glycine, serine and threonine metabolism
Cyanoamino acid metabolism
Glyoxylate and dicarboxylate metabolism
One carbon pool by folate
Methane metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
Biosynthesis of amino acids
Biosynthesis of cofactors
Antifolate resistance

KO part of 5 modules

M00140 Cofactor and vitamin metabolism C1-unit interconversion, prokaryotes
M00141 Cofactor and vitamin metabolism C1-unit interconversion, eukaryotes
M00346 Methane metabolism Formaldehyde assimilation, serine pathway
M00532 Other carbohydrate metabolism Photorespiration
M00975 Serine and threonine metabolism Betaine degradation, bacteria, betaine => pyruvate

Occurence in the database

K00600 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_531 PMI_RS09215 2007901 2009154 -1 glyA serine hydroxymethyltransferase Proteus mirabilis HI4320
1 group_531 FBDBKF_01160 215535 216788 -1 glyA Glycine/serine hydroxymethyltransferase Morganella morganii S1
2 group_531 EHELCC_00385 92080 93333 1 glyA Glycine/serine hydroxymethyltransferase Morganella morganii S2
3 group_531 NLDBIP_03075 586803 588056 -1 glyA Glycine/serine hydroxymethyltransferase Morganella morganii S4
4 group_531 LHKJJB_04590 194044 195297 -1 glyA Glycine/serine hydroxymethyltransferase Morganella morganii S3
5 group_531 HKOGLL_02455 92285 93538 1 glyA Glycine/serine hydroxymethyltransferase Morganella morganii S5
6 group_531 F4V73_RS07235 1504593 1505846 -1 glyA serine hydroxymethyltransferase Morganella psychrotolerans