K00133


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00133, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 14 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00133
KO K00133
Description aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]

KO part of 9 pathways

Glycine, serine and threonine metabolism
Monobactam biosynthesis
Cysteine and methionine metabolism
Lysine biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids

KO part of 7 modules

M00016 Lysine metabolism Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00017 Cysteine and methionine metabolism Methionine biosynthesis, aspartate => homoserine => methionine
M00018 Serine and threonine metabolism Threonine biosynthesis, aspartate => homoserine => threonine
M00033 Serine and threonine metabolism Ectoine biosynthesis, aspartate => ectoine
M00525 Lysine metabolism Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526 Lysine metabolism Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527 Lysine metabolism Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine

Occurence in the database

K00133 is associated with 14 different proteins (see tab "Protein list" and "Profile")
The 14 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1917 PMI_RS08780 1919840 1920850 -1 aspartate-semialdehyde dehydrogenase Proteus mirabilis HI4320
1 group_2077 PMI_RS15520 3451943 3453049 -1 asd aspartate-semialdehyde dehydrogenase Proteus mirabilis HI4320
2 group_1917 FBDBKF_14270 53232 54242 -1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S1
3 group_1917 EHELCC_08010 62743 63753 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S2
4 group_1917 NLDBIP_08335 62743 63753 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S4
5 group_1917 LHKJJB_05930 193406 194416 -1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S3
6 group_1917 HKOGLL_04985 47334 48344 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S5
7 group_2077 FBDBKF_15540 34500 35609 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S1
8 group_2077 EHELCC_15900 33800 34909 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S2
9 group_2077 NLDBIP_16470 45754 46863 -1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S4
10 group_2077 LHKJJB_16335 33800 34909 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S3
11 group_2077 HKOGLL_16105 33800 34909 1 asd aspartate-semialdehyde dehydrogenase Morganella morganii S5
12 group_1917 F4V73_RS02640 556258 557268 1 aspartate-semialdehyde dehydrogenase Morganella psychrotolerans
13 group_2077 F4V73_RS17610 160427 161536 -1 asd aspartate-semialdehyde dehydrogenase Morganella psychrotolerans