K01703


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01703, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01703
KO K01703
Description 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]

KO part of 7 pathways

Valine, leucine and isoleucine biosynthesis
C5-Branched dibasic acid metabolism
Glucosinolate biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids

KO part of 2 modules

M00432 Branched-chain amino acid metabolism Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00535 Branched-chain amino acid metabolism Isoleucine biosynthesis, pyruvate => 2-oxobutanoate

Occurence in the database

K01703 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_871 PMI_RS10275 2253054 2254463 1 leuC 3-isopropylmalate dehydratase large subunit Proteus mirabilis HI4320
1 group_871 FBDBKF_04420 77363 78775 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S1
2 group_871 EHELCC_05710 136820 138232 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S2
3 group_871 NLDBIP_06030 177885 179297 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S4
4 group_871 LHKJJB_02910 155409 156821 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S3
5 group_871 HKOGLL_06385 77273 78685 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S5
6 group_871 F4V73_RS08865 1838494 1839906 1 leuC 3-isopropylmalate dehydratase large subunit Morganella psychrotolerans