K01703


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K01703
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K01703
KO K01703
Description 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]

KO part of 7 pathways

Valine, leucine and isoleucine biosynthesis
C5-Branched dibasic acid metabolism
Glucosinolate biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids

KO part of 2 modules

M00432 Branched-chain amino acid metabolism Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00535 Branched-chain amino acid metabolism Isoleucine biosynthesis, pyruvate => 2-oxobutanoate

Occurence in the database

K01703 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_940 FBDBKF_04420 77363 78775 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S1
1 group_940 EHELCC_05710 136820 138232 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S2
2 group_940 NLDBIP_06030 177885 179297 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S4
3 group_940 LHKJJB_02910 155409 156821 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S3
4 group_940 HKOGLL_06385 77273 78685 1 leuC Homoaconitase/3-isopropylmalate dehydratase large subunit Morganella morganii S5
5 group_940 F4V73_RS08865 1838494 1839906 1 leuC 3-isopropylmalate dehydratase large subunit Morganella psychrotolerans
6 group_940 PMI_RS10275 2253054 2254463 1 leuC 3-isopropylmalate dehydratase large subunit Proteus mirabilis HI4320