K01704


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01704, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01704
KO K01704
Description 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]

KO part of 6 pathways

Valine, leucine and isoleucine biosynthesis
C5-Branched dibasic acid metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids

KO part of 2 modules

M00432 Branched-chain amino acid metabolism Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00535 Branched-chain amino acid metabolism Isoleucine biosynthesis, pyruvate => 2-oxobutanoate

Occurence in the database

K01704 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_872 PMI_RS10280 2254475 2255077 1 leuD 3-isopropylmalate dehydratase small subunit Proteus mirabilis HI4320
1 group_872 FBDBKF_04425 78787 79389 1 leuD 3-isopropylmalate dehydratase small subunit Morganella morganii S1
2 group_872 EHELCC_05715 138244 138846 1 leuD 3-isopropylmalate dehydratase small subunit Morganella morganii S2
3 group_872 NLDBIP_06035 179309 179911 1 leuD 3-isopropylmalate dehydratase small subunit Morganella morganii S4
4 group_872 LHKJJB_02915 156833 157435 1 leuD 3-isopropylmalate dehydratase small subunit Morganella morganii S3
5 group_872 HKOGLL_06390 78697 79299 1 leuD 3-isopropylmalate dehydratase small subunit Morganella morganii S5
6 group_872 F4V73_RS08870 1839921 1840523 1 leuD 3-isopropylmalate dehydratase small subunit Morganella psychrotolerans