K00134


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00134, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00134
KO K00134
Description glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]

KO part of 12 pathways

Glycolysis / Gluconeogenesis
Carbon fixation in photosynthetic organisms
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
Biosynthesis of amino acids
HIF-1 signaling pathway
Alzheimer disease
Pathogenic Escherichia coli infection
Salmonella infection
Diabetic cardiomyopathy

KO part of 6 modules

M00001 Central carbohydrate metabolism Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002 Central carbohydrate metabolism Glycolysis, core module involving three-carbon compounds
M00003 Central carbohydrate metabolism Gluconeogenesis, oxaloacetate => fructose-6P
M00165 Carbon fixation Reductive pentose phosphate cycle (Calvin cycle)
M00308 Central carbohydrate metabolism Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00552 Other carbohydrate metabolism D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P

Occurence in the database

K00134 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_984 PMI_RS07290 1595947 1596942 1 gapA glyceraldehyde-3-phosphate dehydrogenase Proteus mirabilis HI4320
1 group_984 FBDBKF_05435 95745 96740 1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella morganii S1
2 group_984 EHELCC_12155 84754 85749 -1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella morganii S2
3 group_984 NLDBIP_12495 84709 85704 -1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella morganii S4
4 group_984 LHKJJB_12355 84754 85749 -1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella morganii S3
5 group_984 HKOGLL_10970 84754 85749 -1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella morganii S5
6 group_984 F4V73_RS03860 818047 819042 -1 gapA glyceraldehyde-3-phosphate dehydrogenase Morganella psychrotolerans