K00548


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00548, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00548
KO K00548
Description 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]

KO part of 6 pathways

Cysteine and methionine metabolism
Selenocompound metabolism
One carbon pool by folate
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of amino acids

KO part of 1 modules

M00017 Cysteine and methionine metabolism Methionine biosynthesis, aspartate => homoserine => methionine

Occurence in the database

K00548 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_2415 PMI_RS13595 3016297 3019968 -1 metH methionine synthase Proteus mirabilis HI4320
1 group_2415 FBDBKF_19505 4175 7855 1 metH methionine synthase Morganella morganii S1
2 group_2415 EHELCC_16450 4175 7855 1 metH methionine synthase Morganella morganii S2
3 group_2415 NLDBIP_16660 4175 7855 1 metH methionine synthase Morganella morganii S4
4 group_2415 LHKJJB_16810 60655 64335 -1 metH methionine synthase Morganella morganii S3
5 group_2415 HKOGLL_18805 4175 7855 1 metH methionine synthase Morganella morganii S5
6 group_2415 F4V73_RS18620 66573 70253 -1 metH methionine synthase Morganella psychrotolerans