K01754


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01754, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 13 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01754
KO K01754
Description threonine dehydratase [EC:4.3.1.19]

KO part of 6 pathways

Glycine, serine and threonine metabolism
Valine, leucine and isoleucine biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Carbon metabolism
Biosynthesis of amino acids

KO part of 2 modules

M00570 Branched-chain amino acid metabolism Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
M00975 Serine and threonine metabolism Betaine degradation, bacteria, betaine => pyruvate

Occurence in the database

K01754 is associated with 13 different proteins (see tab "Protein list" and "Profile")
The 13 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1321 PMI_RS16420 3620735 3622309 1 ilvA threonine ammonia-lyase, biosynthetic Proteus mirabilis HI4320
1 group_1321 FBDBKF_08180 10140 11708 1 ilvA threonine ammonia-lyase, biosynthetic Morganella morganii S1
2 group_1321 EHELCC_13345 152017 153585 -1 ilvA threonine ammonia-lyase, biosynthetic Morganella morganii S2
3 group_1321 NLDBIP_13685 152017 153585 -1 ilvA threonine ammonia-lyase, biosynthetic Morganella morganii S4
4 group_1321 LHKJJB_12870 8858 10426 1 ilvA threonine ammonia-lyase, biosynthetic Morganella morganii S3
5 group_1321 HKOGLL_12160 152017 153585 -1 ilvA threonine ammonia-lyase, biosynthetic Morganella morganii S5
6 group_2092 FBDBKF_15745 462 1448 1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella morganii S1
7 group_2092 EHELCC_17660 34391 35377 1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella morganii S2
8 group_2092 NLDBIP_19330 10336 11322 1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella morganii S4
9 group_2092 LHKJJB_18100 34391 35377 1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella morganii S3
10 group_2092 HKOGLL_18980 6677 7663 -1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella morganii S5
11 group_2092 F4V73_RS07945 1655608 1656594 -1 tdcB bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB Morganella psychrotolerans
12 group_1321 F4V73_RS18710 9098 10663 1 ilvA threonine ammonia-lyase, biosynthetic Morganella psychrotolerans