K00053


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00053
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00053
KO K00053
Description ketol-acid reductoisomerase [EC:1.1.1.86]

KO part of 6 pathways

Valine, leucine and isoleucine biosynthesis
Pantothenate and CoA biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids

KO part of 2 modules

M00019 Branched-chain amino acid metabolism Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00570 Branched-chain amino acid metabolism Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine

Occurence in the database

K00053 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1380 FBDBKF_08190 12775 14250 1 ilvC ketol-acid reductoisomerase Morganella morganii S1
1 group_1380 EHELCC_13335 149475 150950 -1 ilvC ketol-acid reductoisomerase Morganella morganii S2
2 group_1380 NLDBIP_13675 149475 150950 -1 ilvC ketol-acid reductoisomerase Morganella morganii S4
3 group_1380 LHKJJB_12880 11493 12968 1 ilvC ketol-acid reductoisomerase Morganella morganii S3
4 group_1380 HKOGLL_12150 149475 150950 -1 ilvC ketol-acid reductoisomerase Morganella morganii S5
5 group_1380 F4V73_RS18720 11791 13266 1 ilvC ketol-acid reductoisomerase Morganella psychrotolerans
6 group_1380 PMI_RS16430 3623355 3624830 1 ilvC ketol-acid reductoisomerase Proteus mirabilis HI4320