PF00753


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Pfam domains PF00753, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Pfam domains within the database. 43 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Pfam domain(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Pfam domains has been clustered.
In red the Pfam domains with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Pfam domains prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Pfam domains.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Pfam domains prediction.

Description

External link PF00753
Description Metallo-beta-lactamase superfamily

Occurence in the database

PF00753 is associated with 43 different proteins (see tab "Protein list" and "Profile")
The 43 proteins are classified into 9 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1231 FBDBKF_07170 106623 108923 1 comEC DNA internalization-related competence protein ComEC/Rec2 Morganella morganii S1
1 group_1246 FBDBKF_07245 126721 127368 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S1
2 group_1867 FBDBKF_13955 84066 84821 1 gloB hydroxyacylglutathione hydrolase Morganella morganii S1
3 group_2007 FBDBKF_15080 24571 25449 -1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S1
4 group_2236 FBDBKF_17125 10633 11439 -1 Metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S1
5 group_3667 FBDBKF_20150 2244 3056 -1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S1
6 group_2236 EHELCC_01765 344062 344868 1 Metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S2
7 group_1246 EHELCC_03725 58818 59465 -1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S2
8 group_1231 EHELCC_03800 77263 79563 -1 comEC DNA internalization-related competence protein ComEC/Rec2 Morganella morganii S2
9 group_2007 EHELCC_11165 59457 60335 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S2
10 group_1867 EHELCC_11625 168942 169697 1 gloB hydroxyacylglutathione hydrolase Morganella morganii S2
11 group_2236 NLDBIP_01695 335268 336074 -1 Metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S4
12 group_1246 NLDBIP_03725 58614 59261 -1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S4
13 group_1231 NLDBIP_03800 77059 79359 -1 comEC DNA internalization-related competence protein ComEC/Rec2 Morganella morganii S4
14 group_2007 NLDBIP_11510 59457 60335 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S4
15 group_1867 NLDBIP_11970 168942 169697 1 gloB hydroxyacylglutathione hydrolase Morganella morganii S4
16 group_3667 NLDBIP_19595 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S4
17 group_2236 LHKJJB_00340 56611 57417 1 Metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S3
18 group_1246 LHKJJB_09555 58728 59375 -1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S3
19 group_1231 LHKJJB_09630 77173 79473 -1 comEC DNA internalization-related competence protein ComEC/Rec2 Morganella morganii S3
20 group_2007 LHKJJB_11370 59457 60335 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S3
21 group_1867 LHKJJB_11830 168942 169697 1 gloB hydroxyacylglutathione hydrolase Morganella morganii S3
22 group_3667 LHKJJB_19560 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S3
23 group_2236 HKOGLL_00380 62122 62928 1 Metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S5
24 group_1231 HKOGLL_09345 111579 113879 1 comEC DNA internalization-related competence protein ComEC/Rec2 Morganella morganii S5
25 group_1246 HKOGLL_09420 131677 132324 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S5
26 group_2007 HKOGLL_09980 59457 60335 1 gloB Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II Morganella morganii S5
27 group_1867 HKOGLL_10440 168942 169697 1 gloB hydroxyacylglutathione hydrolase Morganella morganii S5
28 group_3667 HKOGLL_19475 4559 5371 1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1 Morganella morganii S5
29 group_1231 F4V73_RS01355 294766 297093 1 DNA internalization-related competence protein ComEC/Rec2 Morganella psychrotolerans
30 group_1246 F4V73_RS01430 314751 315398 1 MBL fold metallo-hydrolase Morganella psychrotolerans
31 group_3809 F4V73_RS01715 378677 380707 1 alkyl sulfatase dimerization domain-containing protein Morganella psychrotolerans
32 group_2236 F4V73_RS05885 1255082 1255888 -1 MBL fold metallo-hydrolase Morganella psychrotolerans
33 group_2007 F4V73_RS12370 60122 61000 1 MBL fold metallo-hydrolase Morganella psychrotolerans
34 group_3809 F4V73_RS12545 101237 103261 1 alkyl sulfatase dimerization domain-containing protein Morganella psychrotolerans
35 group_1867 F4V73_RS12810 161484 162239 1 gloB hydroxyacylglutathione hydrolase Morganella psychrotolerans
36 group_4175 F4V73_RS16245 60385 61185 -1 MBL fold metallo-hydrolase Morganella psychrotolerans
37 group_1867 PMI_RS01085 269170 269925 -1 gloB hydroxyacylglutathione hydrolase Proteus mirabilis HI4320
38 group_1843 PMI_RS01225 300324 301241 -1 rnz ribonuclease Z Proteus mirabilis HI4320
39 group_2007 PMI_RS01645 392307 393179 -1 MBL fold metallo-hydrolase Proteus mirabilis HI4320
40 group_1231 PMI_RS03525 786165 788534 1 DNA internalization-related competence protein ComEC/Rec2 Proteus mirabilis HI4320
41 group_1246 PMI_RS03600 807046 807696 1 MBL fold metallo-hydrolase Proteus mirabilis HI4320
42 group_2236 PMI_RS07870 1721930 1722748 -1 MBL fold metallo-hydrolase Proteus mirabilis HI4320