Orthogroup:group_3124



Homologs in group_3124

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6 homologs were identified in 5 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_20150 FBDBKF_20150 Morganella morganii S1 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1
NLDBIP_19595 NLDBIP_19595 Morganella morganii S4 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1
LHKJJB_19560 LHKJJB_19560 Morganella morganii S3 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1
HKOGLL_19475 HKOGLL_19475 Morganella morganii S5 blaNDM-1 subclass B1 metallo-beta-lactamase NDM-1
F4V73_RS01715 F4V73_RS01715 Morganella psychrotolerans - alkyl sulfatase dimerization domain-containing protein
F4V73_RS12545 F4V73_RS12545 Morganella psychrotolerans - alkyl sulfatase dimerization domain-containing protein

Distribution of group_3124 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_3124 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_3124

Orthogroup content: 6 members

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This page summarizes the annotation of all members of the orthologous group group_3124.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 blaNDM-1 4
2 - 2

Product

# Product Occurence
1 subclass B1 metallo-beta-lactamase NDM-1 4
2 alkyl sulfatase dimerization domain-containing protein 2

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0491 4 R General function prediction only (R) Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II
COG2015 2 Q Secondary metabolites biosynthesis, transport and catabolism (Q) Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K18780 4 metallo-beta-lactamase class B NDM [EC:3.5.2.6] beta-Lactam resistance Carbapenem resistance
K25227 2 linear primary-alkylsulfatase [EC:3.1.6.21] - -

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00753 6 Metallo-beta-lactamase superfamily
PF14863 2 Alkyl sulfatase dimerisation
PF14864 2 Alkyl sulfatase C-terminal

AMR gene Annotation(s)

Gene Occurences Description Scope Type Class Subclass HMM
blaNDM-1 4 subclass B1 metallo-beta-lactamase NDM-1 core AMR BETA-LACTAM CARBAPENEM NF000259 

Annotations of the 23 SwissProt hits

Annotation Number of occurrences
(R)-specific secondary-alkylsulfatase 1
Alkyl/aryl-sulfatase BDS1 1
Endoribonuclease LACTB2 1
Linear primary-alkylsulfatase 4
Metallo-beta-lactamase type 2 16

Protein length

Min length 270
Max length 676
Mean length (sd) 405.0 (209.1)
Median length 270.0

Protein length distribution