Pyruvate metabolism


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Pyruvate metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Pyruvate metabolism pathway


KO Description #in this genome All occurrences
K00001 alcohol dehydrogenase [EC:1.1.1.1] 0 0
K00002 alcohol dehydrogenase (NADP+) [EC:1.1.1.2] 0 0
K00016 L-lactate dehydrogenase [EC:1.1.1.27] 0 0
K00024 malate dehydrogenase [EC:1.1.1.37] 0 0
K00025 malate dehydrogenase [EC:1.1.1.37] 0 0
K00026 malate dehydrogenase [EC:1.1.1.37] 0 0
K00027 malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] 0 0
K00028 malate dehydrogenase (decarboxylating) [EC:1.1.1.39] 0 0
K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] 2 14
K00049 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] 0 0
K00051 malate dehydrogenase (NADP+) [EC:1.1.1.82] 0 0
K00090 glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215] 1 7
K00101 L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3] 0 0
K00102 D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] 0 0
K00114 alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8] 0 0
K00116 malate dehydrogenase (quinone) [EC:1.1.5.4] 1 1
K00121 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] 1 7
K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] 1 7
K00132 acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10] 1 1
K00138 aldehyde dehydrogenase [EC:1.2.1.-] 0 0
K00149 aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] 0 0
K00156 pyruvate dehydrogenase (quinone) [EC:1.2.5.1] 1 7
K00158 pyruvate oxidase [EC:1.2.3.3] 0 0
K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] 0 0
K00162 pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] 0 0
K00163 pyruvate dehydrogenase E1 component [EC:1.2.4.1] 1 7
K00169 pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] 0 0
K00170 pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] 0 0
K00171 pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] 0 0
K00172 pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] 0 0
K00174 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 0 0
K00175 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] 0 0
K00189 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1] 0 0
K00233 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12] 0 0
K00244 succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 0 0
K00245 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] 1 7
K00246 succinate dehydrogenase subunit C 1 7
K00247 succinate dehydrogenase subunit D 1 7
K00382 dihydrolipoyl dehydrogenase [EC:1.8.1.4] 1 7
K00467 lactate 2-monooxygenase [EC:1.13.12.4] 0 0
K00625 phosphate acetyltransferase [EC:2.3.1.8] 0 0
K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1 13
K00627 pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] 1 7
K00656 formate C-acetyltransferase [EC:2.3.1.54] 1 7
K00873 pyruvate kinase [EC:2.7.1.40] 3 15
K00925 acetate kinase [EC:2.7.2.1] 1 7
K01003 oxaloacetate decarboxylase [EC:4.1.1.112] 0 0
K01006 pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0 0
K01007 pyruvate, water dikinase [EC:2.7.9.2] 1 7
K01026 propionate CoA-transferase [EC:2.8.3.1] 0 0
K01067 acetyl-CoA hydrolase [EC:3.1.2.1] 0 0
K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6] 2 14
K01512 acylphosphatase [EC:3.6.1.7] 0 5
K01571 oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 0 0
K01573 oxaloacetate decarboxylase (Na+ extruding) subunit gamma 0 0
K01595 phosphoenolpyruvate carboxylase [EC:4.1.1.31] 1 7
K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] 0 0
K01610 phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1 7
K01638 malate synthase [EC:2.3.3.9] 1 1
K01649 2-isopropylmalate synthase [EC:2.3.3.13] 1 7
K01655 homocitrate synthase [EC:2.3.3.14] 0 0
K01675 fumarate hydratase D [EC:4.2.1.2] 0 0
K01676 fumarate hydratase, class I [EC:4.2.1.2] 0 6
K01677 fumarate hydratase subunit alpha [EC:4.2.1.2] 0 0
K01678 fumarate hydratase subunit beta [EC:4.2.1.2] 0 0
K01679 fumarate hydratase, class II [EC:4.2.1.2] 1 7
K01759 lactoylglutathione lyase [EC:4.4.1.5] 1 7
K01774 fumarate hydratase E [EC:4.2.1.2] 0 0
K01895 acetyl-CoA synthetase [EC:6.2.1.1] 1 7
K01905 acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] 0 0
K01913 acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2] 0 0
K01946 acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] 0 0
K01958 pyruvate carboxylase [EC:6.4.1.1] 0 0
K01959 pyruvate carboxylase subunit A [EC:6.4.1.1] 0 0
K01960 pyruvate carboxylase subunit B [EC:6.4.1.1] 0 0
K01961 acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] 1 7
K01962 acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] 2 14
K01963 acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] 1 7
K02160 acetyl-CoA carboxylase biotin carboxyl carrier protein 1 7
K02594 homocitrate synthase NifV [EC:2.3.3.14] 0 0
K03737 pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 0 5
K03777 D-lactate dehydrogenase (quinone) [EC:1.1.5.12] 1 7
K03778 D-lactate dehydrogenase [EC:1.1.1.28] 1 7
K04020 phosphotransacetylase 0 6
K04021 aldehyde dehydrogenase 0 5
K04022 alcohol dehydrogenase 0 6
K04072 acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1 6
K04073 acetaldehyde dehydrogenase [EC:1.2.1.10] 0 0
K05523 D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124] 0 0
K07248 lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21] 0 0
K10977 methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] 0 0
K11262 acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] 0 0
K11263 acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14] 0 0
K12406 pyruvate kinase isozymes R/L [EC:2.7.1.40] 0 0
K12957 alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183] 0 0
K12972 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] 1 7
K13788 phosphate acetyltransferase [EC:2.3.1.8] 1 7
K13951 alcohol dehydrogenase 1/7 [EC:1.1.1.1] 0 0
K13952 alcohol dehydrogenase 6 [EC:1.1.1.1] 0 0
K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] 0 6
K13954 alcohol dehydrogenase [EC:1.1.1.1] 1 1
K13979 alcohol dehydrogenase (NADP+) [EC:1.1.1.2] 0 0
K13980 alcohol dehydrogenase 4 [EC:1.1.1.1] 0 0
K14028 methanol dehydrogenase (cytochrome c) subunit 1 [EC:1.1.2.7] 0 0
K14029 methanol dehydrogenase (cytochrome c) subunit 2 [EC:1.1.2.7] 0 0
K14085 aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] 0 0
K15024 putative phosphotransacetylase [EC:2.3.1.8] 1 1
K17741 NADPH-dependent methylglyoxal reductase [EC:1.1.1.283] 0 0
K18118 succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] 0 0
K18366 acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87] 0 0
K18472 acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15] 0 0
K18857 alcohol dehydrogenase class-P [EC:1.1.1.1] 0 0
K18881 D-lactate dehydratase [EC:4.2.1.130] 0 0
K18930 D-lactate dehydrogenase 0 0
K19266 lactaldehyde dehydrogenase [EC:1.2.1.22] 0 0
K20370 phosphoenolpyruvate carboxykinase (diphosphate) [EC:4.1.1.38] 0 0
K20509 carboxybiotin decarboxylase [EC:7.2.4.1] 0 0
K21618 (R)-2-hydroxyglutarate---pyruvate transhydrogenase [EC:1.1.99.40] 0 0
K21836 D-lactate dehydrogenase (acceptor) [EC:1.1.99.6] 0 0
K22211 D-lactate dehydratase [EC:4.2.1.130] 0 0
K22212 malolactic enzyme [EC:4.1.1.101] 0 0
K22224 acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] 0 0
K22373 lactate racemase [EC:5.1.2.1] 0 0
K22473 alcohol dehydrogenase (quinone), dehydrogenase subunit [EC:1.1.5.5] 0 0
K22474 alcohol dehydrogenase (quinone), cytochrome c subunit [EC:1.1.5.5] 0 0
K23257 methylglyoxal/glyoxal reductase [EC:1.1.1.283 1.1.1.-] 0 0
K24012 acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] 0 0
K25995 succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12] 0 0
K25996 succinate dehydrogenase subunit C 0 0
K26113 lactate dehydrogenase (NAD+,ferredoxin) subunit LctD [EC:1.1.1.436] 0 0
K26114 lactate dehydrogenase (NAD+,ferredoxin) subunit LctC 0 0
K26115 lactate dehydrogenase (NAD+,ferredoxin) subunit LctB 0 0
K26318 fumarate reductase (cytochrome) [EC:1.3.2.4] 0 0