K00626


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00626, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 13 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00626
KO K00626
Description acetyl-CoA C-acetyltransferase [EC:2.3.1.9]

KO part of 17 pathways

Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Benzoate degradation
Tryptophan metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Butanoate metabolism
Carbon fixation pathways in prokaryotes
Terpenoid backbone biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
Fatty acid metabolism
Two-component system
Fat digestion and absorption

KO part of 7 modules

M00088 Lipid metabolism Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone
M00095 Terpenoid backbone biosynthesis C5 isoprenoid biosynthesis, mevalonate pathway
M00373 Other carbohydrate metabolism Ethylmalonyl pathway
M00374 Carbon fixation Dicarboxylate-hydroxybutyrate cycle
M00375 Carbon fixation Hydroxypropionate-hydroxybutylate cycle
M00849 Terpenoid backbone biosynthesis C5 isoprenoid biosynthesis, mevalonate pathway, archaea
M00957 Lysine metabolism Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA

Occurence in the database

K00626 is associated with 13 different proteins (see tab "Protein list" and "Profile")
The 13 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1932 PMI_RS08865 1938811 1940115 -1 fadI acetyl-CoA C-acyltransferase FadI Proteus mirabilis HI4320
1 group_2849 FBDBKF_10610 83454 84635 1 paaJ Acetyl-CoA acetyltransferase Morganella morganii S1
2 group_2849 EHELCC_14945 83444 84625 1 paaJ Acetyl-CoA acetyltransferase Morganella morganii S2
3 group_2849 NLDBIP_14775 83444 84625 1 paaJ Acetyl-CoA acetyltransferase Morganella morganii S4
4 group_2849 LHKJJB_14570 57101 58282 -1 paaJ Acetyl-CoA acetyltransferase Morganella morganii S3
5 group_2849 HKOGLL_13190 57101 58282 -1 paaJ Acetyl-CoA acetyltransferase Morganella morganii S5
6 group_1932 FBDBKF_14365 73449 74741 -1 fadI acetyl-CoA C-acyltransferase FadI Morganella morganii S1
7 group_1932 EHELCC_07915 42244 43536 1 fadI acetyl-CoA C-acyltransferase FadI Morganella morganii S2
8 group_1932 NLDBIP_08240 42244 43536 1 fadI acetyl-CoA C-acyltransferase FadI Morganella morganii S4
9 group_1932 LHKJJB_06025 213623 214915 -1 fadI acetyl-CoA C-acyltransferase FadI Morganella morganii S3
10 group_1932 HKOGLL_04890 26835 28127 1 fadI acetyl-CoA C-acyltransferase FadI Morganella morganii S5
11 group_1932 F4V73_RS02540 535785 537077 1 fadI acetyl-CoA C-acyltransferase FadI Morganella psychrotolerans
12 group_2849 F4V73_RS14320 85998 87182 1 acetyl-CoA C-acetyltransferase Morganella psychrotolerans