K00382


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00382, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00382
KO K00382
Description dihydrolipoyl dehydrogenase [EC:1.8.1.4]

KO part of 16 pathways

Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Glycine, serine and threonine metabolism
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
Lipoic acid metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of cofactors

KO part of 7 modules

M00009 Central carbohydrate metabolism Citrate cycle (TCA cycle, Krebs cycle)
M00011 Central carbohydrate metabolism Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00032 Lysine metabolism Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00036 Branched-chain amino acid metabolism Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00307 Central carbohydrate metabolism Pyruvate oxidation, pyruvate => acetyl-CoA
M00532 Other carbohydrate metabolism Photorespiration
M00621 Serine and threonine metabolism Glycine cleavage system

Occurence in the database

K00382 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_838 PMI_RS10075 2199158 2200585 -1 lpdA dihydrolipoyl dehydrogenase Proteus mirabilis HI4320
1 group_838 FBDBKF_04225 30969 32396 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S1
2 group_838 EHELCC_05515 90426 91853 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S2
3 group_838 NLDBIP_05835 131491 132918 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S4
4 group_838 LHKJJB_02715 109015 110442 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S3
5 group_838 HKOGLL_06190 30879 32306 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S5
6 group_838 F4V73_RS08675 1792037 1793464 -1 lpdA dihydrolipoyl dehydrogenase Morganella psychrotolerans