K00382


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00382
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00382
KO K00382
Description dihydrolipoyl dehydrogenase [EC:1.8.1.4]

KO part of 17 pathways

Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Glycine, serine and threonine metabolism
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
One carbon pool by folate
Lipoic acid metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of cofactors

KO part of 7 modules

M00009 Central carbohydrate metabolism Citrate cycle (TCA cycle, Krebs cycle)
M00011 Central carbohydrate metabolism Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00032 Lysine metabolism Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00036 Branched-chain amino acid metabolism Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00307 Central carbohydrate metabolism Pyruvate oxidation, pyruvate => acetyl-CoA
M00532 Other carbohydrate metabolism Photorespiration
M00621 Serine and threonine metabolism Glycine cleavage system

Occurence in the database

K00382 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_907 FBDBKF_04225 30969 32396 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S1
1 group_907 EHELCC_05515 90426 91853 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S2
2 group_907 NLDBIP_05835 131491 132918 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S4
3 group_907 LHKJJB_02715 109015 110442 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S3
4 group_907 HKOGLL_06190 30879 32306 -1 lpdA dihydrolipoyl dehydrogenase Morganella morganii S5
5 group_907 F4V73_RS08675 1792037 1793464 -1 lpdA dihydrolipoyl dehydrogenase Morganella psychrotolerans
6 group_907 PMI_RS10075 2199158 2200585 -1 lpdA dihydrolipoyl dehydrogenase Proteus mirabilis HI4320