Homologs in group_589

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6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_01720 FBDBKF_01720 82.0 Morganella morganii S1 hemB porphobilinogen synthase
EHELCC_02190 EHELCC_02190 82.0 Morganella morganii S2 hemB porphobilinogen synthase
NLDBIP_01270 NLDBIP_01270 82.0 Morganella morganii S4 hemB porphobilinogen synthase
LHKJJB_00765 LHKJJB_00765 82.0 Morganella morganii S3 hemB porphobilinogen synthase
HKOGLL_00805 HKOGLL_00805 82.0 Morganella morganii S5 hemB porphobilinogen synthase
F4V73_RS04050 F4V73_RS04050 82.0 Morganella psychrotolerans hemB porphobilinogen synthase

Distribution of the homologs in the orthogroup group_589

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_589

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0ACB3 0.0 508 77 0 319 3 hemB Delta-aminolevulinic acid dehydratase Shigella flexneri
P0ACB2 0.0 508 77 0 319 1 hemB Delta-aminolevulinic acid dehydratase Escherichia coli (strain K12)
O67876 2.92e-112 332 52 1 306 3 hemB Delta-aminolevulinic acid dehydratase Aquifex aeolicus (strain VF5)
Q9K8G2 7.66e-110 325 51 1 321 3 hemB Delta-aminolevulinic acid dehydratase Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Q9ZMR8 1.07e-109 325 51 4 323 3 hemB Delta-aminolevulinic acid dehydratase Helicobacter pylori (strain J99 / ATCC 700824)
P56074 2.39e-108 321 50 3 321 3 hemB Delta-aminolevulinic acid dehydratase Helicobacter pylori (strain ATCC 700392 / 26695)
P43087 7.42e-107 317 51 2 318 3 hemB Delta-aminolevulinic acid dehydratase Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805)
Q8CNZ0 9.4e-106 315 50 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HNN5 9.4e-106 315 50 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
P30950 2.25e-105 313 49 1 318 3 hemB Delta-aminolevulinic acid dehydratase Bacillus subtilis (strain 168)
O28305 2.01e-104 311 49 3 315 3 hemB Delta-aminolevulinic acid dehydratase Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
P64335 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain MW2)
Q6G8Q7 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain MSSA476)
Q6GG37 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain MRSA252)
P64334 4.67e-103 308 49 2 315 1 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain N315)
P64333 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q5HFA4 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain COL)
Q2FXR3 4.67e-103 308 49 2 315 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus (strain NCTC 8325 / PS 47)
P0C1R9 1.36e-100 301 49 2 309 3 hemB Delta-aminolevulinic acid dehydratase Staphylococcus aureus
Q02250 3.45e-99 298 46 3 314 3 hemB Delta-aminolevulinic acid dehydratase Methanothermus sociabilis
P77923 2.03e-95 288 45 1 321 3 hemB Delta-aminolevulinic acid dehydratase Propionibacterium freudenreichii subsp. freudenreichii
Q60178 4.94e-95 288 46 3 320 3 hemB Delta-aminolevulinic acid dehydratase Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
O26839 5.15e-94 285 48 4 319 3 hemB Delta-aminolevulinic acid dehydratase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
P77969 8.48e-94 284 50 3 317 3 hemB Delta-aminolevulinic acid dehydratase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q42836 5.32e-93 286 49 6 314 2 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Hordeum vulgare
Q5Z8V9 6.23e-93 285 48 6 314 2 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Oryza sativa subsp. japonica
Q9SFH9 1.12e-92 285 47 6 318 2 HEMB1 Delta-aminolevulinic acid dehydratase 1, chloroplastic Arabidopsis thaliana
P24493 9.74e-92 283 47 6 318 1 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Spinacia oleracea
O84638 1.45e-91 279 46 2 311 3 hemB Delta-aminolevulinic acid dehydratase Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx)
Q43058 6.56e-91 280 50 6 318 2 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Physcomitrium patens
P30124 1.85e-90 278 48 6 310 1 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic (Fragment) Pisum sativum
P45623 2.83e-90 278 48 6 317 3 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Selaginella martensii
Q59334 8.81e-90 274 46 1 302 1 hemB Delta-aminolevulinic acid dehydratase Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)
P54919 2.41e-89 273 48 3 316 3 hemB Delta-aminolevulinic acid dehydratase Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q8KCJ0 8.81e-89 271 45 1 302 3 hemB Delta-aminolevulinic acid dehydratase Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
P9WMP5 3.9e-88 270 47 3 317 1 hemB Delta-aminolevulinic acid dehydratase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WMP4 3.9e-88 270 47 3 317 3 hemB Delta-aminolevulinic acid dehydratase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P46723 8.7e-88 269 45 3 317 3 hemB Delta-aminolevulinic acid dehydratase Mycobacterium leprae (strain TN)
Q9Z7G1 9.55e-87 266 44 3 330 3 hemB Delta-aminolevulinic acid dehydratase Chlamydia pneumoniae
Q94LA4 2.54e-86 268 46 6 322 3 HEMB2 Probable delta-aminolevulinic acid dehydratase 2, chloroplastic Arabidopsis thaliana
P43210 4.05e-86 268 48 6 318 2 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Glycine max
P45622 5.54e-86 265 46 2 318 1 hemB Delta-aminolevulinic acid dehydratase Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
Q9PLU4 1.37e-83 258 42 3 331 3 hemB Delta-aminolevulinic acid dehydratase Chlamydia muridarum (strain MoPn / Nigg)
Q42682 1.74e-81 255 43 6 323 2 HEMB Delta-aminolevulinic acid dehydratase, chloroplastic Chlamydomonas reinhardtii
P10518 7.29e-77 241 44 6 301 1 Alad Delta-aminolevulinic acid dehydratase Mus musculus
P06214 1.18e-74 236 43 6 301 1 Alad Delta-aminolevulinic acid dehydratase Rattus norvegicus
Q59643 1.29e-74 236 42 5 322 1 hemB Delta-aminolevulinic acid dehydratase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P42504 1.1e-73 233 44 2 313 1 hemB Delta-aminolevulinic acid dehydratase Rhodobacter capsulatus
Q58DK5 1.48e-73 233 43 5 300 2 ALAD Delta-aminolevulinic acid dehydratase Bos taurus
Q55E06 2.17e-72 230 41 5 306 3 alad Delta-aminolevulinic acid dehydratase Dictyostelium discoideum
P13716 3.79e-72 229 42 5 302 1 ALAD Delta-aminolevulinic acid dehydratase Homo sapiens
Q60HH9 2.73e-70 224 41 5 302 2 ALAD Delta-aminolevulinic acid dehydratase Macaca fascicularis
Q5R971 5.81e-70 223 42 5 300 2 ALAD Delta-aminolevulinic acid dehydratase Pongo abelii
P05373 1.51e-62 205 40 5 305 1 HEM2 Delta-aminolevulinic acid dehydratase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
O42768 1.75e-62 204 39 5 304 1 HEM2 Delta-aminolevulinic acid dehydratase Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
Q750E0 7.48e-62 203 39 5 303 3 HEM2 Delta-aminolevulinic acid dehydratase Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Q59295 2.27e-61 197 47 0 204 3 hemB Delta-aminolevulinic acid dehydratase (Fragment) Ruminiclostridium josui
P78974 3.82e-57 190 38 6 314 2 hem2 Delta-aminolevulinic acid dehydratase Schizosaccharomyces pombe (strain 972 / ATCC 24843)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS07040
Feature type CDS
Gene hemB
Product porphobilinogen synthase
Location 1535091 - 1536068 (strand: 1)
Length 978 (nucleotides) / 325 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_589
Orthogroup size 7
N. genomes 7

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Genomic region

Domains

PF00490 Delta-aminolevulinic acid dehydratase

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0113 Coenzyme transport and metabolism (H) H Delta-aminolevulinic acid dehydratase, porphobilinogen synthase

Kegg Ortholog Annotation(s)

Protein Sequence

MSNEQSIQRLRRLRQSENLRALFQETTLSKNDLALPIFVEEGLEDYQPIKSMPGVVRIPEKRLAYEIERIAKAGIKTVMTFGVSHHLDETGSDAWKSDGLVSRMSRICKDAVPEMIVMSDTCFCEYTSHGHCGVLHGEHVDNDETIHNLGLQAVAAAQAGADFIAPSAAMDGQVAAIRAALDQAGFTDTGIVSYSTKFASALYGPFRDAAGSRLIGDRKTYQMNPMNRREAIRESLIDEQEGADMLMVKPAGAYLDIIRDVRERTLLPLAAYQISGEYAQIKFAALAGAIDEDRVVMETLGSIKRAGADLILSYFALDLAERNLL

Flanking regions ( +/- flanking 50bp)

ATAATACTTTAGTAAATAATCATTAGAACTGGCCATAACAAGGAGATATTGTGAGCAACGAACAATCCATCCAGCGATTAAGAAGACTACGCCAGTCAGAGAACCTGCGCGCGCTGTTTCAAGAAACGACACTCAGCAAAAATGATCTAGCCCTACCTATTTTCGTTGAAGAAGGCTTAGAGGATTATCAGCCGATCAAAAGTATGCCAGGTGTGGTACGTATTCCTGAAAAACGCCTTGCTTATGAAATTGAGCGTATCGCTAAAGCGGGTATCAAAACGGTCATGACCTTTGGTGTCTCACACCATCTTGATGAAACAGGTAGCGACGCTTGGAAAAGCGACGGTCTAGTTTCTCGCATGTCTCGTATTTGTAAAGATGCTGTACCAGAAATGATTGTTATGTCAGATACTTGTTTCTGTGAATATACTTCACACGGACACTGTGGCGTTTTACATGGTGAACATGTCGATAATGATGAAACTATCCATAATTTAGGTCTACAGGCGGTTGCCGCCGCACAAGCTGGTGCTGATTTTATTGCTCCCTCTGCCGCAATGGATGGTCAAGTTGCCGCTATTCGTGCTGCATTAGATCAAGCAGGATTTACCGATACCGGTATTGTTTCCTACTCAACTAAATTTGCTTCTGCATTATATGGCCCATTCCGTGATGCTGCTGGCTCTCGCTTAATTGGTGATCGTAAAACATATCAAATGAATCCGATGAATCGTCGGGAAGCTATCCGCGAATCATTGATTGATGAGCAAGAAGGTGCGGATATGTTAATGGTTAAGCCTGCTGGTGCTTATTTAGATATTATTCGTGATGTTCGTGAACGTACACTATTACCGTTAGCAGCCTACCAAATTAGTGGGGAGTATGCGCAAATCAAATTTGCTGCATTAGCGGGTGCTATCGATGAAGATCGCGTGGTAATGGAAACACTAGGCTCCATTAAACGCGCAGGTGCTGATTTAATTCTCTCTTACTTTGCGCTTGATTTAGCAGAAAGAAATCTACTTTAATCACCCTTGTATCTAGATGACAAGTGAATAGATCACTAGGAATCTTCAGT