K01698


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01698, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01698
KO K01698
Description porphobilinogen synthase [EC:4.2.1.24]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 4 modules

M00121 Cofactor and vitamin metabolism Heme biosynthesis, plants and bacteria, glutamate => heme
M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868 Cofactor and vitamin metabolism Heme biosynthesis, animals and fungi, glycine => heme
M00926 Cofactor and vitamin metabolism Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme

Occurence in the database

K01698 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_589 PMI_RS07040 1535091 1536068 1 hemB porphobilinogen synthase Proteus mirabilis HI4320
1 group_589 FBDBKF_01720 32969 33943 -1 hemB porphobilinogen synthase Morganella morganii S1
2 group_589 EHELCC_02190 420789 421763 -1 hemB porphobilinogen synthase Morganella morganii S2
3 group_589 NLDBIP_01270 258373 259347 1 hemB porphobilinogen synthase Morganella morganii S4
4 group_589 LHKJJB_00765 133338 134312 -1 hemB porphobilinogen synthase Morganella morganii S3
5 group_589 HKOGLL_00805 138849 139823 -1 hemB porphobilinogen synthase Morganella morganii S5
6 group_589 F4V73_RS04050 856742 857716 -1 hemB porphobilinogen synthase Morganella psychrotolerans