M00846


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Kegg module M00846 is descriptive of Siroheme biosynthesis, glutamyl-tRNA => siroheme module, which is part of the Metabolism of cofactors and vitamins category and Cofactor and vitamin metabolism subcategory.

In General the list of Ko entries of M00846 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Siroheme biosynthesis, glutamyl-tRNA => siroheme module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00846 Kegg module

Id Description
K00589 uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
K01698 porphobilinogen synthase [EC:4.2.1.24]
K01719 uroporphyrinogen-III synthase [EC:4.2.1.75]
K01749 hydroxymethylbilane synthase [EC:2.5.1.61]
K01845 glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
K02302 uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
K02304 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K02492 glutamyl-tRNA reductase [EC:1.2.1.70]
K02496 uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
K03794 sirohydrochlorin ferrochelatase [EC:4.99.1.4]
K13542 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K13543 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K24866 precorrin-2 dehydrogenase [EC:1.3.1.76]