Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Porphyrin metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Porphyrin metabolism pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00214 | biliverdin reductase [EC:1.3.1.24] | 0 | 0 |
| K00218 | protochlorophyllide reductase [EC:1.3.1.33] | 0 | 0 |
| K00228 | coproporphyrinogen III oxidase [EC:1.3.3.3] | 1 | 7 |
| K00230 | menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] | 1 | 7 |
| K00231 | protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] | 0 | 0 |
| K00435 | hydrogen peroxide-dependent heme synthase [EC:1.3.98.5] | 0 | 0 |
| K00510 | heme oxygenase 1 [EC:1.14.14.18] | 0 | 0 |
| K00589 | uroporphyrin-III C-methyltransferase [EC:2.1.1.107] | 0 | 0 |
| K00595 | precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:2.1.1.132 2.1.1.289 2.1.1.196] | 0 | 0 |
| K00643 | 5-aminolevulinate synthase [EC:2.3.1.37] | 0 | 0 |
| K00699 | glucuronosyltransferase [EC:2.4.1.17] | 0 | 0 |
| K00768 | nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21] | 0 | 6 |
| K00798 | cob(I)alamin adenosyltransferase [EC:2.5.1.17] | 0 | 0 |
| K01195 | beta-glucuronidase [EC:3.2.1.31] | 0 | 0 |
| K01599 | uroporphyrinogen decarboxylase [EC:4.1.1.37] | 1 | 7 |
| K01698 | porphobilinogen synthase [EC:4.2.1.24] | 1 | 7 |
| K01719 | uroporphyrinogen-III synthase [EC:4.2.1.75] | 1 | 7 |
| K01749 | hydroxymethylbilane synthase [EC:2.5.1.61] | 1 | 7 |
| K01764 | cytochrome c heme-lyase [EC:4.4.1.17] | 0 | 0 |
| K01772 | protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] | 1 | 7 |
| K01845 | glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] | 1 | 7 |
| K01885 | glutamyl-tRNA synthetase [EC:6.1.1.17] | 1 | 7 |
| K02188 | cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] | 0 | 6 |
| K02189 | cobalt-precorrin 5A hydrolase [EC:3.7.1.12] | 0 | 6 |
| K02190 | sirohydrochlorin cobaltochelatase [EC:4.99.1.3] | 0 | 6 |
| K02191 | cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] | 0 | 6 |
| K02224 | cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] | 0 | 6 |
| K02225 | cobalamin biosynthesis protein CobC | 0 | 0 |
| K02226 | alpha-ribazole phosphatase [EC:3.1.3.73] | 0 | 6 |
| K02227 | adenosylcobinamide-phosphate synthase [EC:6.3.1.10] | 0 | 6 |
| K02228 | precorrin-6A synthase [EC:2.1.1.152] | 0 | 0 |
| K02229 | precorrin-3B synthase [EC:1.14.13.83] | 0 | 0 |
| K02230 | cobaltochelatase CobN [EC:6.6.1.2] | 0 | 0 |
| K02231 | adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] | 0 | 6 |
| K02232 | adenosylcobyric acid synthase [EC:6.3.5.10] | 0 | 6 |
| K02233 | adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] | 0 | 6 |
| K02257 | heme o synthase [EC:2.5.1.141] | 1 | 7 |
| K02259 | heme a synthase [EC:1.17.99.9] | 0 | 0 |
| K02302 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] | 2 | 2 |
| K02303 | uroporphyrin-III C-methyltransferase [EC:2.1.1.107] | 0 | 6 |
| K02304 | precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4] | 0 | 0 |
| K02492 | glutamyl-tRNA reductase [EC:1.2.1.70] | 1 | 7 |
| K02495 | oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3] | 2 | 14 |
| K02496 | uroporphyrin-III C-methyltransferase [EC:2.1.1.107] | 1 | 7 |
| K03394 | precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] | 0 | 6 |
| K03399 | cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] | 0 | 6 |
| K03403 | magnesium chelatase subunit H [EC:6.6.1.1] | 0 | 0 |
| K03404 | magnesium chelatase subunit D [EC:6.6.1.1] | 0 | 0 |
| K03405 | magnesium chelatase subunit I [EC:6.6.1.1] | 0 | 0 |
| K03428 | magnesium-protoporphyrin O-methyltransferase [EC:2.1.1.11] | 0 | 0 |
| K03594 | bacterioferritin [EC:1.16.3.1] | 1 | 7 |
| K03794 | sirohydrochlorin ferrochelatase [EC:4.99.1.4] | 0 | 0 |
| K03795 | sirohydrochlorin cobaltochelatase [EC:4.99.1.3] | 0 | 0 |
| K04032 | ethanolamine utilization cobalamin adenosyltransferase [EC:2.5.1.154] | 0 | 6 |
| K04034 | anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase [EC:1.21.98.3] | 0 | 0 |
| K04035 | magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81] | 0 | 0 |
| K04036 | divinyl protochlorophyllide a 8-vinyl-reductase [EC:1.-.-.-] | 0 | 0 |
| K04037 | light-independent protochlorophyllide reductase subunit L [EC:1.3.7.7] | 0 | 0 |
| K04038 | light-independent protochlorophyllide reductase subunit N [EC:1.3.7.7] | 0 | 0 |
| K04039 | light-independent protochlorophyllide reductase subunit B [EC:1.3.7.7] | 0 | 0 |
| K04040 | chlorophyll/bacteriochlorophyll a synthase [EC:2.5.1.62 2.5.1.133] | 0 | 0 |
| K04720 | threonine-phosphate decarboxylase [EC:4.1.1.81] | 0 | 6 |
| K05369 | 15,16-dihydrobiliverdin:ferredoxin oxidoreductase [EC:1.3.7.2] | 0 | 0 |
| K05370 | phycoerythrobilin:ferredoxin oxidoreductase [EC:1.3.7.3] | 0 | 0 |
| K05371 | phycocyanobilin:ferredoxin oxidoreductase [EC:1.3.7.5] | 0 | 0 |
| K05895 | precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] | 0 | 6 |
| K05901 | biliverdin reductase / flavin reductase [EC:1.3.1.24 1.5.1.30] | 0 | 0 |
| K05934 | precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] | 0 | 6 |
| K05936 | precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] | 0 | 6 |
| K06042 | precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] | 0 | 6 |
| K07145 | heme oxygenase (staphylobilin-producing) [EC:1.14.99.48] | 0 | 0 |
| K07215 | heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58] | 0 | 0 |
| K07226 | heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58] | 0 | 0 |
| K08099 | chlorophyllase [EC:3.1.1.14] | 0 | 0 |
| K08100 | bilirubin oxidase [EC:1.3.3.5] | 0 | 0 |
| K08101 | phytochromobilin:ferredoxin oxidoreductase [EC:1.3.7.4] | 0 | 0 |
| K08260 | adenosylcobinamide hydrolase [EC:3.5.1.90] | 0 | 0 |
| K08973 | protoporphyrinogen IX oxidase [EC:1.3.99.-] | 0 | 0 |
| K09882 | cobaltochelatase CobS [EC:6.6.1.2] | 1 | 2 |
| K09883 | cobaltochelatase CobT [EC:6.6.1.2] | 1 | 2 |
| K10960 | geranylgeranyl diphosphate/geranylgeranyl-bacteriochlorophyllide a reductase [EC:1.3.1.83 1.3.1.111] | 0 | 0 |
| K11333 | 3,8-divinyl chlorophyllide a/chlorophyllide a reductase subunit X [EC:1.3.7.14 1.3.7.15] | 0 | 0 |
| K11334 | 3,8-divinyl chlorophyllide a/chlorophyllide a reductase subunit Y [EC:1.3.7.14 1.3.7.15] | 0 | 0 |
| K11335 | 3,8-divinyl chlorophyllide a/chlorophyllide a reductase subunit Z [EC:1.3.7.14 1.3.7.15] | 0 | 0 |
| K11336 | 3-vinyl bacteriochlorophyllide hydratase [EC:4.2.1.165] | 0 | 0 |
| K11337 | bacteriochlorophyllide a dehydrogenase [EC:1.1.1.396] | 0 | 0 |
| K13071 | pheophorbide a oxygenase [EC:1.14.15.17] | 0 | 0 |
| K13540 | precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase [EC:2.1.1.130 2.1.1.131] | 0 | 0 |
| K13541 | cobalt-precorrin 5A hydrolase / cobalt-factor III methyltransferase / precorrin-3B C17-methyltransferase [EC:3.7.1.12 2.1.1.272 2.1.1.131] | 0 | 0 |
| K13542 | uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] | 0 | 0 |
| K13543 | uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] | 0 | 0 |
| K13544 | pheophorbidase [EC:3.1.1.82] | 0 | 0 |
| K13545 | red chlorophyll catabolite reductase [EC:1.3.7.12] | 0 | 0 |
| K13600 | chlorophyllide a oxygenase [EC:1.14.13.122] | 0 | 0 |
| K13601 | bacteriochlorophyllide d C-8(2)-methyltransferase [EC:2.1.1.332] | 0 | 0 |
| K13602 | bacteriochlorophyllide d C-12(1)-methyltransferase [EC:2.1.1.331] | 0 | 0 |
| K13603 | 3-vinyl bacteriochlorophyllide hydratase [EC:4.2.1.169] | 0 | 0 |
| K13604 | bacteriochlorophyllide d C-20 methyltransferase [EC:2.1.1.333] | 0 | 0 |
| K13605 | bacteriochlorophyll c synthase [EC:2.5.1.-] | 0 | 0 |
| K13606 | chlorophyll(ide) b reductase [EC:1.1.1.294] | 0 | 0 |
| K13624 | ceruloplasmin [EC:1.16.3.1] | 0 | 0 |
| K13786 | cob(II)yrinic acid a,c-diamide reductase [EC:1.16.8.-] | 0 | 0 |
| K14163 | bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] | 0 | 0 |
| K14735 | hephaestin [EC:1.16.3.1] | 0 | 0 |
| K16651 | L-threonine kinase [EC:2.7.1.177] | 0 | 6 |
| K18010 | 7-hydroxymethyl chlorophyll a reductase [EC:1.17.7.2] | 0 | 0 |
| K19054 | frataxin [EC:1.16.3.1] | 0 | 0 |
| K19073 | divinyl chlorophyllide a 8-vinyl-reductase [EC:1.3.1.75] | 0 | 0 |
| K19221 | cob(I)alamin adenosyltransferase [EC:2.5.1.17] | 1 | 7 |
| K19712 | adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] | 0 | 0 |
| K21058 | chlorophyllide a hydrolase [EC:3.1.1.100] | 0 | 0 |
| K21231 | 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin) [EC:1.3.7.13] | 0 | 0 |
| K21312 | bacteriochlorophyllide c C-7(1)-hydroxylase [EC:1.17.98.2] | 0 | 0 |
| K21418 | heme oxygenase 2 [EC:1.14.14.18] | 0 | 0 |
| K21479 | cobalt-factor III methyltransferase [EC:2.1.1.272] | 0 | 0 |
| K21480 | heme oxygenase (biliverdin-producing, ferredoxin) [EC:1.14.15.20] | 0 | 0 |
| K21610 | Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbC [EC:6.3.3.7] | 0 | 0 |
| K21611 | Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7] | 0 | 0 |
| K21612 | coenzyme F430 synthetase [EC:6.4.1.9] | 0 | 0 |
| K21796 | Prochlorococcus phage phycoerythrobilin synthase [EC:1.3.7.6] | 0 | 0 |
| K22011 | sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11] | 0 | 0 |
| K22012 | Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12] | 0 | 0 |
| K22013 | magnesium dechelatase [EC:4.99.1.10] | 0 | 0 |
| K22225 | siroheme decarboxylase [EC:4.1.1.111] | 0 | 0 |
| K22226 | Fe-coproporphyrin III synthase | 0 | 0 |
| K22227 | AdoMet-dependent heme synthase [EC:1.3.98.6] | 0 | 0 |
| K22316 | ribonuclease H / adenosylcobalamin/alpha-ribazole phosphatase [EC:3.1.26.4 3.1.3.73] | 0 | 0 |
| K22336 | bacterioferritin B [EC:1.16.3.1] | 0 | 0 |
| K22465 | 5-hydroxybenzimidazole synthase [EC:4.1.99.23] | 0 | 0 |
| K22466 | 5-hydroxybenzimidazole synthase [EC:4.1.99.23] | 0 | 0 |
| K22552 | multicopper oxidase [EC:1.16.3.1] | 0 | 0 |
| K23825 | F420H(2)-dependent biliverdin reductase [EC:1.3.98.-] | 0 | 0 |
| K24866 | precorrin-2 dehydrogenase [EC:1.3.1.76] | 0 | 6 |
| K24867 | dihydro-heme d1 dehydrogenase | 0 | 0 |
| K25033 | hydrogen peroxide-dependent heme synthase [EC:1.3.98.5] | 0 | 0 |
| K25496 | adenosylcobalamin phosphodiesterase | 0 | 0 |
| K25497 | 5-hydroxybenzimidazole methyltransferase [EC:2.1.1.-] | 0 | 0 |
| K25498 | 5-methoxybenzimidazole methyltransferase | 0 | 0 |
| K25499 | 5-methoxy-6-methylbenzimidazole methyltransferase | 0 | 0 |