K01719


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01719, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01719
KO K01719
Description uroporphyrinogen-III synthase [EC:4.2.1.75]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 4 modules

M00121 Cofactor and vitamin metabolism Heme biosynthesis, plants and bacteria, glutamate => heme
M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868 Cofactor and vitamin metabolism Heme biosynthesis, animals and fungi, glycine => heme
M00926 Cofactor and vitamin metabolism Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme

Occurence in the database

K01719 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1342 PMI_RS16575 3652517 3653254 -1 hemD uroporphyrinogen-III synthase Proteus mirabilis HI4320
1 group_1342 FBDBKF_08320 38626 39363 -1 hemD uroporphyrinogen-III synthase Morganella morganii S1
2 group_1342 EHELCC_13205 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S2
3 group_1342 NLDBIP_13545 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S4
4 group_1342 LHKJJB_13010 37344 38081 -1 hemD uroporphyrinogen-III synthase Morganella morganii S3
5 group_1342 HKOGLL_12020 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S5
6 group_1342 F4V73_RS09520 3309 4046 -1 hemD uroporphyrinogen-III synthase Morganella psychrotolerans