K01719


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K01719
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K01719
KO K01719
Description uroporphyrinogen-III synthase [EC:4.2.1.75]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 4 modules

M00121 Cofactor and vitamin metabolism Heme biosynthesis, plants and bacteria, glutamate => heme
M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868 Cofactor and vitamin metabolism Heme biosynthesis, animals and fungi, glycine => heme
M00926 Cofactor and vitamin metabolism Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme

Occurence in the database

K01719 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1398 FBDBKF_08320 38626 39363 -1 hemD uroporphyrinogen-III synthase Morganella morganii S1
1 group_1398 EHELCC_13205 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S2
2 group_1398 NLDBIP_13545 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S4
3 group_1398 LHKJJB_13010 37344 38081 -1 hemD uroporphyrinogen-III synthase Morganella morganii S3
4 group_1398 HKOGLL_12020 124362 125099 1 hemD uroporphyrinogen-III synthase Morganella morganii S5
5 group_1398 F4V73_RS09520 3309 4046 -1 hemD uroporphyrinogen-III synthase Morganella psychrotolerans
6 group_1398 PMI_RS16575 3652517 3653254 -1 hemD uroporphyrinogen-III synthase Proteus mirabilis HI4320