K02224


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K02224, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 6 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K02224
KO K02224
Description cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]

KO part of 3 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 2 modules

M00924 Cofactor and vitamin metabolism Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
M00925 Cofactor and vitamin metabolism Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide

Occurence in the database

K02224 is associated with 6 different proteins (see tab "Protein list" and "Profile")
The 6 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_3093 FBDBKF_18915 25925 27310 -1 cobB cobyrinate a,c-diamide synthase Morganella morganii S1
1 group_3093 EHELCC_17110 25926 27311 -1 cobB cobyrinate a,c-diamide synthase Morganella morganii S2
2 group_3093 NLDBIP_18490 25925 27310 -1 cobB cobyrinate a,c-diamide synthase Morganella morganii S4
3 group_3093 LHKJJB_09135 165019 166404 1 cobB cobyrinate a,c-diamide synthase Morganella morganii S3
4 group_3093 HKOGLL_08685 165019 166404 1 cobB cobyrinate a,c-diamide synthase Morganella morganii S5
5 group_3093 F4V73_RS13680 372560 373945 1 cobyrinate a,c-diamide synthase Morganella psychrotolerans