K02303


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K02303, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 6 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K02303
KO K02303
Description uroporphyrin-III C-methyltransferase [EC:2.1.1.107]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 3 modules

M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00924 Cofactor and vitamin metabolism Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
M00925 Cofactor and vitamin metabolism Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide

Occurence in the database

K02303 is associated with 6 different proteins (see tab "Protein list" and "Profile")
The 6 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_296 FBDBKF_07445 441 1226 1 cobA Uroporphyrinogen-III methylase (siroheme synthase) Morganella morganii S1
1 group_296 EHELCC_17115 28091 28876 1 cobA Uroporphyrinogen-III methylase (siroheme synthase) Morganella morganii S2
2 group_296 NLDBIP_18495 28090 28875 1 cobA Uroporphyrinogen-III methylase (siroheme synthase) Morganella morganii S4
3 group_296 LHKJJB_09130 163454 164239 -1 cobA Uroporphyrinogen-III methylase (siroheme synthase) Morganella morganii S3
4 group_296 HKOGLL_08680 163454 164239 -1 cobA Uroporphyrinogen-III methylase (siroheme synthase) Morganella morganii S5
5 group_296 F4V73_RS13675 370979 371764 -1 cobA uroporphyrinogen-III C-methyltransferase Morganella psychrotolerans