K01749


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01749, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01749
KO K01749
Description hydroxymethylbilane synthase [EC:2.5.1.61]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 4 modules

M00121 Cofactor and vitamin metabolism Heme biosynthesis, plants and bacteria, glutamate => heme
M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868 Cofactor and vitamin metabolism Heme biosynthesis, animals and fungi, glycine => heme
M00926 Cofactor and vitamin metabolism Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme

Occurence in the database

K01749 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1343 PMI_RS16580 3653251 3654192 -1 hemC hydroxymethylbilane synthase Proteus mirabilis HI4320
1 group_1343 FBDBKF_08325 39360 40301 -1 hemC hydroxymethylbilane synthase Morganella morganii S1
2 group_1343 EHELCC_13200 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S2
3 group_1343 NLDBIP_13540 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S4
4 group_1343 LHKJJB_13015 38078 39019 -1 hemC hydroxymethylbilane synthase Morganella morganii S3
5 group_1343 HKOGLL_12015 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S5
6 group_1343 F4V73_RS09525 4043 4984 -1 hemC hydroxymethylbilane synthase Morganella psychrotolerans