K01749


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K01749
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K01749
KO K01749
Description hydroxymethylbilane synthase [EC:2.5.1.61]

KO part of 5 pathways

Porphyrin metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of cofactors

KO part of 4 modules

M00121 Cofactor and vitamin metabolism Heme biosynthesis, plants and bacteria, glutamate => heme
M00846 Cofactor and vitamin metabolism Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868 Cofactor and vitamin metabolism Heme biosynthesis, animals and fungi, glycine => heme
M00926 Cofactor and vitamin metabolism Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme

Occurence in the database

K01749 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1399 FBDBKF_08325 39360 40301 -1 hemC hydroxymethylbilane synthase Morganella morganii S1
1 group_1399 EHELCC_13200 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S2
2 group_1399 NLDBIP_13540 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S4
3 group_1399 LHKJJB_13015 38078 39019 -1 hemC hydroxymethylbilane synthase Morganella morganii S3
4 group_1399 HKOGLL_12015 123424 124365 1 hemC hydroxymethylbilane synthase Morganella morganii S5
5 group_1399 F4V73_RS09525 4043 4984 -1 hemC hydroxymethylbilane synthase Morganella psychrotolerans
6 group_1399 PMI_RS16580 3653251 3654192 -1 hemC hydroxymethylbilane synthase Proteus mirabilis HI4320