Homologs in group_57

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12 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_00420 FBDBKF_00420 40.9 Morganella morganii S1 metC cystathionine beta-lyase
FBDBKF_02700 FBDBKF_02700 39.5 Morganella morganii S1 metC cystathionine beta-lyase
EHELCC_01125 EHELCC_01125 40.9 Morganella morganii S2 metC cystathionine beta-lyase
EHELCC_03170 EHELCC_03170 39.5 Morganella morganii S2 metC cystathionine beta-lyase
NLDBIP_00290 NLDBIP_00290 39.5 Morganella morganii S4 metC cystathionine beta-lyase
NLDBIP_02335 NLDBIP_02335 40.9 Morganella morganii S4 metC cystathionine beta-lyase
LHKJJB_01745 LHKJJB_01745 39.5 Morganella morganii S3 metC cystathionine beta-lyase
LHKJJB_03850 LHKJJB_03850 40.9 Morganella morganii S3 metC cystathionine beta-lyase
HKOGLL_01785 HKOGLL_01785 39.5 Morganella morganii S5 metC cystathionine beta-lyase
HKOGLL_03195 HKOGLL_03195 40.9 Morganella morganii S5 metC cystathionine beta-lyase
F4V73_RS05195 F4V73_RS05195 39.8 Morganella psychrotolerans metC cystathionine beta-lyase
PMI_RS00135 PMI_RS00135 40.5 Proteus mirabilis HI4320 metC cystathionine beta-lyase

Distribution of the homologs in the orthogroup group_57

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_57

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
Q07703 1.21e-100 306 43 4 369 1 metC Cystathionine beta-lyase Bordetella avium
P44527 2.17e-96 296 39 5 391 3 metC Cystathionine beta-lyase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P06721 1.21e-93 289 40 7 389 1 metC Cystathionine beta-lyase MetC Escherichia coli (strain K12)
P18949 4.93e-93 287 40 7 391 3 metC Cystathionine beta-lyase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q52811 1.65e-92 286 40 6 390 3 metC Putative cystathionine beta-lyase Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841)
Q73GL9 6.86e-85 266 36 3 393 1 aar L-alanine/L-glutamate racemase Wolbachia pipientis wMel
Q1M0P5 6.91e-73 235 35 7 391 1 metB Cystathionine gamma-synthase Helicobacter pylori
P56069 5.61e-72 233 35 7 390 1 metB Cystathionine gamma-synthase Helicobacter pylori (strain ATCC 700392 / 26695)
Q9ZMW7 1.09e-69 227 35 7 391 3 metB Cystathionine gamma-synthase Helicobacter pylori (strain J99 / ATCC 700824)
P43623 2.19e-66 217 35 2 328 1 IRC7 Putative cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
A2RM21 1.09e-64 214 32 7 387 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris (strain MG1363)
P0A4K2 1.09e-64 214 32 7 387 3 metC Cystathionine beta-lyase Lactococcus lactis subsp. lactis (strain IL1403)
Q60HG7 1.75e-63 211 37 9 346 2 CTH Cystathionine gamma-lyase Macaca fascicularis
Q83A83 5.01e-63 209 33 9 399 1 metC Cystathionine beta-lyase Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Q55DV9 1e-62 209 32 7 386 1 cysA Cystathionine gamma-lyase Dictyostelium discoideum
Q19QT7 7.27e-62 207 37 9 344 2 CTH Cystathionine gamma-lyase Sus scrofa
P0C2T9 1.48e-61 206 32 7 387 1 metC Cystathionine beta-lyase Lactococcus lactis subsp. cremoris
P18757 4.56e-60 202 36 9 344 1 Cth Cystathionine gamma-lyase Rattus norvegicus
Q8VCN5 2.32e-59 200 36 9 344 1 Cth Cystathionine gamma-lyase Mus musculus
P32929 2.78e-56 192 38 9 346 1 CTH Cystathionine gamma-lyase Homo sapiens
O05394 2.78e-55 189 32 9 391 1 mccB Cystathionine gamma-lyase Bacillus subtilis (strain 168)
Q58DW2 9.32e-55 189 35 9 329 2 CTH Cystathionine gamma-lyase Bos taurus
P46807 3.53e-54 186 31 5 384 3 metB Cystathionine gamma-synthase Mycobacterium leprae (strain TN)
A0A0J6G7P5 6.2e-54 186 33 7 391 3 megL L-methionine gamma-lyase Pseudomonas deceptionensis
P9WGB7 3.47e-53 184 31 5 383 1 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB6 3.47e-53 184 31 5 383 3 metB Cystathionine gamma-synthase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
P66876 3.47e-53 184 31 5 383 3 metB Cystathionine gamma-synthase Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Q9X0Z7 1.2e-52 182 29 5 387 1 aar L-alanine/L-glutamate racemase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Q8L0X4 1.27e-52 182 30 8 391 1 mgl L-methionine gamma-lyase Fusobacterium nucleatum subsp. polymorphum
P55216 1.75e-52 182 35 7 340 3 cth-2 Putative cystathionine gamma-lyase 2 Caenorhabditis elegans
Q7MX71 6.94e-52 181 31 11 403 1 mgl L-methionine gamma-lyase Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
O31632 3.26e-51 179 30 7 390 1 metC Cystathionine beta-lyase MetC Bacillus subtilis (strain 168)
P00935 4.4e-50 176 31 9 405 1 metB Cystathionine gamma-synthase Escherichia coli (strain K12)
Q8RDT4 1.67e-49 174 29 8 391 1 FN1419 L-methionine gamma-lyase Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
P55217 8.49e-49 176 28 7 388 1 CGS1 Cystathionine gamma-synthase 1, chloroplastic Arabidopsis thaliana
P13254 1e-48 172 31 9 394 1 mdeA L-methionine gamma-lyase Pseudomonas putida
Q9C876 1.83e-46 167 29 6 381 3 CGS2 Probable cystathionine gamma-synthase 2 Arabidopsis thaliana
Q73KL7 8.36e-46 165 30 10 393 1 megL L-methionine gamma-lyase Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
P53780 2.06e-45 165 31 6 337 1 At3g57050 Cystathionine beta-lyase, chloroplastic Arabidopsis thaliana
P24601 9.05e-45 160 32 5 309 3 metB Probable cystathionine gamma-synthase (Fragment) Herpetosiphon aurantiacus
A0A0M3VI47 5.55e-44 161 31 7 341 1 CBL Cystathionine beta-lyase, chloroplastic Mimosa pudica
P31373 8.83e-44 159 32 6 330 1 CYS3 Cystathionine gamma-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P55218 4.48e-43 157 32 4 332 1 metZ O-succinylhomoserine sulfhydrylase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q1K8G0 3.03e-41 154 31 10 340 1 met-2 Cystathionine beta-lyase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
O31631 3.86e-39 146 27 9 398 1 metI Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase Bacillus subtilis (strain 168)
Q4L332 3.4e-38 144 30 8 345 1 metC Cystathionine beta-lyase MetC Staphylococcus haemolyticus (strain JCSC1435)
P0DXD3 5.7e-37 141 29 8 391 1 Rleg2_5066 Canavanine gamma-lyase Rhizobium leguminosarum bv. trifolii (strain WSM2304)
P0DXC4 8.78e-37 140 28 9 392 1 JFQ02_10020 Canavanine gamma-lyase Pseudomonas canavaninivorans
P44502 3.55e-36 138 28 7 342 3 metB Cystathionine gamma-synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q59829 1.83e-35 137 29 8 344 3 cysA Putative cystathionine gamma-lyase Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
A8CEI3 3.14e-34 134 27 9 363 1 None Mimosinase, chloroplastic Leucaena leucocephala
Q79VI4 4.29e-34 134 28 10 428 1 metY O-acetyl-L-homoserine sulfhydrylase Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
P9WGB5 1.53e-32 129 28 5 340 1 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WGB4 1.53e-32 129 28 5 340 3 metZ O-succinylhomoserine sulfhydrylase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
U6BYK3 8.1e-32 128 27 8 339 1 None Mimosinase, chloroplastic Mimosa pudica
Q9WZY4 1.09e-30 125 26 13 426 1 TM_0882 O-acetyl-L-homoserine sulfhydrylase Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
O13326 3.81e-30 123 25 9 421 1 met17 Homocysteine synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
O94350 6.17e-29 119 27 12 353 3 str3 Cystathionine beta-lyase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q92441 3.73e-28 118 26 12 444 3 MET17 Homocysteine/cysteine synthase Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
P94890 1.22e-26 114 25 8 432 1 metY O-acetyl-L-homoserine sulfhydrylase Leptospira meyeri
Q9SGU9 1.42e-26 113 31 9 293 1 MGL Methionine gamma-lyase Arabidopsis thaliana
P50125 1.59e-26 113 27 8 367 1 cysD Homocysteine synthase Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Q5MNH8 2.28e-26 113 26 11 419 2 lolC2 Sulfhydrylase-like protein lolC2 Epichloe uncinata
Q5SK88 2.86e-26 112 27 12 426 1 oah1 O-acetyl-L-homoserine sulfhydrylase 1 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
S0DUX5 1.67e-25 110 26 11 425 1 FUB7 Sulfhydrylase FUB7 Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
A0A0D2YG02 2.17e-25 110 27 11 425 1 FUB7 Sulfhydrylase FUB7 Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)
W7MS09 6.04e-25 108 26 11 425 1 FUB7 Sulfhydrylase FUB7 Gibberella moniliformis (strain M3125 / FGSC 7600)
P38716 3.54e-24 105 26 14 397 1 YHR112C Uncharacterized trans-sulfuration enzyme YHR112C Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q8J0B2 1.57e-23 105 26 11 419 2 lolC1 Sulfhydrylase-like protein lolC1 Epichloe uncinata
P06106 2.27e-23 104 26 11 416 1 MET17 Homocysteine/cysteine synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P53101 1.62e-22 102 26 17 417 1 STR3 Cystathionine beta-lyase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q5SJ58 2.29e-22 101 25 10 402 1 oah2 O-acetyl-L-homoserine sulfhydrylase 2 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Q826W3 4.23e-21 97 28 7 336 1 mgl L-methionine gamma-lyase Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
P38675 8.61e-17 85 29 8 264 3 met-7 Cystathionine gamma-synthase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
O74314 5.31e-16 83 26 11 327 3 SPBC15D4.09c Probable cystathionine gamma-synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
O42851 3.44e-15 80 28 6 258 1 SPAC23A1.14c Uncharacterized trans-sulfuration enzyme C23A1.14c Schizosaccharomyces pombe (strain 972 / ATCC 24843)
A0A397HQN2 5.09e-11 67 25 9 317 1 ankD Cystathionine gamma-synthase-like protein ankD Aspergillus thermomutatus
A0A0C2WKN7 2.36e-05 50 21 13 349 2 iboG1 Cystathionine gamma-synthase-like enzyme iboG1 Amanita muscaria (strain Koide BX008)
G8XHD7 0.000461 45 23 8 244 1 besB L-2-amino-4-chloropent-4-enoate dechlorinase/desaturase Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS03085
Feature type CDS
Gene metC
Product cystathionine beta-lyase
Location 678743 - 679918 (strand: -1)
Length 1176 (nucleotides) / 391 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_57
Orthogroup size 13
N. genomes 7

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Genomic region

Domains

PF01053 Cys/Met metabolism PLP-dependent enzyme

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0626 Amino acid transport and metabolism (E) E Cystathionine beta-lyase/cystathionine gamma-synthase

Protein Sequence

MKQNKQTTLIHSGRQAIKTSGPINPPVMRASTIVFDSIKSWREIRDRRITERVLSYGARGTETAFALEALVTELEGGYRAQLFPTGLAAIAFTIMGYARSGGHVLFADSVYEPVRKIASAFLEPNNITYSFFKTDGSDFEQKIQENTQLIFVESPGSLLYEMLDLPEICHIAHEKNIPVGVDNTWGSAWLYNPLELGADVSVIAATKYLCGHSDVMMGIMIANETAWKQIGALPEALGQASSPDDAALVLRGMRTLAQRLTNHGKSALAIAQWLETRPEVAKVWFPELPTHPRHDLWKRDCKGSNGLLTIEFKQKYTIKQSEQFIDALTLFGIGASWGGFESLALPANVMGARTATDWREGHGPFVRLHIGLESTDDLIADLTQAFSALNQ

Flanking regions ( +/- flanking 50bp)

CTAAATTAATTACTGGGAGATCTTATTTTCTATATTCGGAGATATAAATAGTGAAACAGAATAAACAAACAACATTGATACATAGTGGGCGTCAAGCAATTAAAACATCTGGCCCAATTAACCCTCCTGTTATGAGAGCCAGTACTATTGTTTTTGATTCAATAAAAAGCTGGCGTGAAATACGCGATCGTCGTATTACTGAACGAGTATTAAGCTATGGTGCTCGTGGTACAGAAACAGCGTTTGCACTTGAAGCATTAGTAACTGAATTAGAAGGTGGTTATCGAGCACAGCTCTTTCCTACAGGGCTAGCCGCAATTGCATTTACTATTATGGGCTACGCCCGAAGTGGTGGGCATGTTTTATTTGCTGATTCTGTCTATGAACCCGTACGTAAAATAGCCTCTGCTTTTTTAGAGCCTAATAATATCACTTATAGCTTTTTTAAAACTGACGGTTCAGATTTCGAGCAAAAAATTCAAGAAAACACTCAACTTATTTTCGTTGAATCACCGGGTTCATTACTTTATGAAATGCTGGATCTACCAGAAATTTGCCATATCGCTCATGAAAAAAATATTCCTGTTGGGGTGGATAATACTTGGGGCTCGGCATGGCTTTATAACCCTTTGGAATTAGGTGCTGATGTTTCTGTAATTGCTGCAACTAAATATTTATGCGGTCACTCAGATGTCATGATGGGCATTATGATCGCAAATGAAACCGCATGGAAACAAATTGGGGCATTACCAGAAGCTCTTGGTCAAGCAAGTAGCCCTGATGATGCCGCCTTAGTCCTGAGAGGAATGAGGACTCTTGCTCAACGTCTTACAAATCATGGTAAATCAGCACTGGCTATCGCTCAGTGGTTAGAAACACGCCCTGAAGTGGCCAAAGTTTGGTTTCCAGAGTTACCCACACATCCTCGCCATGACTTATGGAAACGTGATTGTAAAGGTAGTAATGGATTATTAACCATTGAATTTAAACAAAAATATACCATTAAACAATCTGAACAATTTATTGATGCATTAACCTTATTTGGTATTGGTGCATCTTGGGGAGGATTTGAAAGTCTTGCATTACCCGCCAATGTTATGGGTGCCAGAACAGCAACAGATTGGCGTGAAGGCCACGGTCCTTTTGTACGTTTACATATTGGTCTTGAGTCTACTGATGACTTAATTGCAGATCTCACCCAAGCATTTAGTGCATTAAATCAATAACAACAATACTGCATCACGACACTGGGGAATTAATTATGACTGGTTTAATT