Cysteine and methionine metabolism


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Cysteine and methionine metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Cysteine and methionine metabolism pathway


KO Description #in this genome All occurrences
K00003 homoserine dehydrogenase [EC:1.1.1.3] 0 0
K00016 L-lactate dehydrogenase [EC:1.1.1.27] 0 0
K00024 malate dehydrogenase [EC:1.1.1.37] 0 0
K00025 malate dehydrogenase [EC:1.1.1.37] 0 0
K00026 malate dehydrogenase [EC:1.1.1.37] 0 0
K00058 D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1 7
K00133 aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] 2 14
K00456 cysteine dioxygenase [EC:1.13.11.20] 0 0
K00544 betaine-homocysteine S-methyltransferase [EC:2.1.1.5] 0 0
K00547 homocysteine S-methyltransferase [EC:2.1.1.10] 0 0
K00548 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] 1 7
K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] 1 7
K00552 glycine N-methyltransferase [EC:2.1.1.20] 0 0
K00558 DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 0 8
K00640 serine O-acetyltransferase [EC:2.3.1.30] 2 9
K00641 homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] 0 0
K00651 homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] 1 7
K00772 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] 0 0
K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] 1 7
K00797 spermidine synthase [EC:2.5.1.16] 0 0
K00802 spermine synthase [EC:2.5.1.22] 0 0
K00811 aspartate aminotransferase, chloroplastic [EC:2.6.1.1] 0 0
K00812 aspartate aminotransferase [EC:2.6.1.1] 0 0
K00813 aspartate aminotransferase [EC:2.6.1.1] 1 7
K00815 tyrosine aminotransferase [EC:2.6.1.5] 0 0
K00816 kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] 0 0
K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] 1 7
K00827 alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40] 0 0
K00831 phosphoserine aminotransferase [EC:2.6.1.52] 1 7
K00832 aromatic-amino-acid transaminase [EC:2.6.1.57] 1 7
K00837 aromatic aminotransferase [EC:2.6.1.-] 0 0
K00838 aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5] 0 0
K00899 5-methylthioribose kinase [EC:2.7.1.100] 0 6
K00928 aspartate kinase [EC:2.7.2.4] 1 7
K01011 thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] 1 7
K01243 adenosylhomocysteine nucleosidase [EC:3.2.2.9] 1 7
K01244 5'-methylthioadenosine nucleosidase [EC:3.2.2.16] 0 0
K01251 adenosylhomocysteinase [EC:3.13.2.1] 0 6
K01505 1-aminocyclopropane-1-carboxylate deaminase [EC:3.5.99.7] 0 0
K01566 S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9] 0 0
K01611 S-adenosylmethionine decarboxylase [EC:4.1.1.50] 0 0
K01697 cystathionine beta-synthase [EC:4.2.1.22] 0 0
K01738 cysteine synthase [EC:2.5.1.47] 1 7
K01739 cystathionine gamma-synthase [EC:2.5.1.48] 1 1
K01740 O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1 7
K01752 L-serine dehydratase [EC:4.3.1.17] 2 14
K01758 cystathionine gamma-lyase [EC:4.4.1.1] 0 0
K01760 cysteine-S-conjugate beta-lyase [EC:4.4.1.13] 0 0
K01761 methionine-gamma-lyase [EC:4.4.1.11] 1 7
K01762 1-aminocyclopropane-1-carboxylate synthase [EC:4.4.1.14] 0 0
K01767 S-methyl-1-thioxylulose 5-phosphate methylthiotransferase [EC:2.8.4.6] 0 0
K01919 glutamate--cysteine ligase [EC:6.3.2.2] 1 7
K01920 glutathione synthase [EC:6.3.2.3] 1 7
K03334 L-amino-acid oxidase [EC:1.4.3.2] 0 0
K05396 D-cysteine desulfhydrase [EC:4.4.1.15] 0 0
K05810 purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] 1 7
K05933 aminocyclopropanecarboxylate oxidase [EC:1.14.17.4] 0 0
K05953 nicotianamine synthase [EC:2.5.1.43] 0 0
K07173 S-ribosylhomocysteine lyase [EC:4.4.1.21] 1 7
K08963 methylthioribose-1-phosphate isomerase [EC:5.3.1.23] 0 6
K08964 methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] 0 0
K08965 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [EC:5.3.2.5] 0 0
K08966 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [EC:3.1.3.87] 0 0
K08967 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] 0 0
K08968 L-methionine (R)-S-oxide reductase [EC:1.8.4.14] 1 7
K08969 L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117] 0 0
K09758 aspartate 4-decarboxylase [EC:4.1.1.12] 0 0
K09880 enolase-phosphatase E1 [EC:3.1.3.77] 0 0
K10150 cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22] 0 0
K10764 O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] 0 0
K11204 glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2] 0 0
K11205 glutamate--cysteine ligase regulatory subunit 0 0
K11358 aspartate aminotransferase [EC:2.6.1.1] 0 0
K12339 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] 1 7
K12524 bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] 1 7
K12525 bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3] 1 7
K12526 bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4] 0 0
K12960 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] 1 7
K13034 L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9] 0 0
K13060 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K13061 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K13062 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K14155 cysteine-S-conjugate beta-lyase [EC:4.4.1.13] 1 13
K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] 0 0
K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] 0 0
K16054 methylthioribulose 1-phosphate dehydratase / enolase-phosphatase E1 [EC:4.2.1.109 3.1.3.77] 0 0
K16843 (S)-sulfolactate dehydrogenase [EC:1.1.1.310] 0 0
K16844 (2R)-3-sulfolactate dehydrogenase (NADP+) [EC:1.1.1.338] 0 0
K16845 (2R)-sulfolactate sulfo-lyase subunit alpha [EC:4.4.1.24] 0 0
K16846 (2R)-sulfolactate sulfo-lyase subunit beta [EC:4.4.1.24] 0 0
K17069 O-acetylhomoserine/O-acetylserine sulfhydrylase [EC:2.5.1.49 2.5.1.47] 0 0
K17216 cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134] 0 0
K17217 cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2] 0 0
K17398 DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] 0 0
K17399 DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37] 0 0
K17462 putative AdoMet-dependent methyltransferase [EC:2.1.1.-] 0 0
K17950 L-cysteate sulfo-lyase [EC:4.4.1.25] 0 0
K17989 L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] 0 0
K18284 adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30] 0 0
K19696 5'-methylthioinosine phosphorylase [EC:2.4.2.44] 0 0
K20021 L-cysteine desulfidase [EC:4.4.1.28] 0 0
K20248 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K20249 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K20250 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K20772 1-aminocyclopropane-1-carboxylate synthase 1/2/6 [EC:4.4.1.14] 0 0
K21456 glutathione synthase [EC:6.3.2.3] 0 0
K21623 L-cystine beta-lyase [EC:4.4.1.35] 0 0
K22207 L-cysteine desulfhydrase [EC:4.4.1.28] 0 0
K22846 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] 0 0
K22847 S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent) [EC:2.8.5.1] 0 0
K22954 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K22955 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K22956 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K22957 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K22968 acyl homoserine lactone synthase [EC:2.3.1.184] 0 0
K23304 serine O-acetyltransferase [EC:2.3.1.30] 0 0
K23370 L-serine kinase (ADP) [EC:2.7.1.226] 0 0
K23975 L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16] 0 0
K23976 L-aspartate semialdehyde sulfurtransferase ferredoxin 0 0
K23977 L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117] 0 0
K24034 spermidine synthase / saccharopine dehydrogenase (NADP+, L-glutamate-forming) [EC:2.5.1.16 1.5.1.10] 0 0
K24042 methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] 0 0
K25035 S-methyl-5-thioribulose 1-phosphate isomerase [EC:5.3.3.23] 0 0
K25316 amino-acid racemase [EC:5.1.1.10] 0 0
K25317 amino-acid racemase [EC:5.1.1.10] 1 1