K01625


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01625, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 14 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01625
KO K01625
Description 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]

KO part of 5 pathways

Pentose phosphate pathway
Glyoxylate and dicarboxylate metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Carbon metabolism

KO part of 4 modules

M00008 Central carbohydrate metabolism Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00061 Other carbohydrate metabolism D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
M00308 Central carbohydrate metabolism Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00631 Other carbohydrate metabolism D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P

Occurence in the database

K01625 is associated with 14 different proteins (see tab "Protein list" and "Profile")
The 14 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1611 PMI_RS10580 2327828 2328466 1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase Proteus mirabilis HI4320
1 group_2413 PMI_RS13610 3023309 3023950 1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase Proteus mirabilis HI4320
2 group_1611 FBDBKF_10580 76477 77112 1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S1
3 group_1611 EHELCC_14915 76467 77102 1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S2
4 group_1611 NLDBIP_14745 76467 77102 1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S4
5 group_1611 LHKJJB_14600 64624 65259 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S3
6 group_1611 HKOGLL_13220 64624 65259 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S5
7 group_2413 FBDBKF_19495 1361 2002 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S1
8 group_2413 EHELCC_16440 1361 2002 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S2
9 group_2413 NLDBIP_16650 1361 2002 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S4
10 group_2413 LHKJJB_16820 66508 67149 1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S3
11 group_2413 HKOGLL_18795 1361 2002 -1 eda 2-keto-3-deoxy-6-phosphogluconate aldolase Morganella morganii S5
12 group_2413 F4V73_RS18630 72463 73104 1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase Morganella psychrotolerans
13 group_1611 F4V73_RS14290 78949 79584 1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase Morganella psychrotolerans