K01495


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K01495
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K01495
KO K01495
Description GTP cyclohydrolase IA [EC:3.5.4.16]

KO part of 3 pathways

Folate biosynthesis
Metabolic pathways
Biosynthesis of cofactors

KO part of 5 modules

M00126 Cofactor and vitamin metabolism Tetrahydrofolate biosynthesis, GTP => THF
M00841 Cofactor and vitamin metabolism Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
M00842 Cofactor and vitamin metabolism Tetrahydrobiopterin biosynthesis, GTP => BH4
M00843 Cofactor and vitamin metabolism L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
M00988 Cofactor and vitamin metabolism PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine

Occurence in the database

K01495 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1237 FBDBKF_06790 20913 21572 1 folE GTP cyclohydrolase I FolE Morganella morganii S1
1 group_1237 EHELCC_04180 164614 165273 -1 folE GTP cyclohydrolase I FolE Morganella morganii S2
2 group_1237 NLDBIP_04180 164410 165069 -1 folE GTP cyclohydrolase I FolE Morganella morganii S4
3 group_1237 LHKJJB_10010 164524 165183 -1 folE GTP cyclohydrolase I FolE Morganella morganii S3
4 group_1237 HKOGLL_08965 25869 26528 1 folE GTP cyclohydrolase I FolE Morganella morganii S5
5 group_1237 F4V73_RS00930 197667 198326 1 folE GTP cyclohydrolase I FolE Morganella psychrotolerans
6 group_1237 PMI_RS03150 695247 695909 1 folE GTP cyclohydrolase I FolE Proteus mirabilis HI4320