Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Folate biosynthesis Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Folate biosynthesis pathway
| KO | Description | All occurrences |
|---|---|---|
| K00011 | aldehyde reductase [EC:1.1.1.21] | 0 |
| K00072 | sepiapterin reductase [EC:1.1.1.153] | 0 |
| K00079 | carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] | 0 |
| K00287 | dihydrofolate reductase [EC:1.5.1.3] | 8 |
| K00310 | pyrimidodiazepine synthase [EC:1.5.4.1] | 0 |
| K00357 | dihydropteridine reductase [EC:1.5.1.34] | 0 |
| K00500 | phenylalanine-4-hydroxylase [EC:1.14.16.1] | 0 |
| K00501 | tyrosine 3-monooxygenase [EC:1.14.16.2] | 0 |
| K00502 | tryptophan 5-monooxygenase [EC:1.14.16.4] | 0 |
| K00796 | dihydropteroate synthase [EC:2.5.1.15] | 7 |
| K00950 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] | 7 |
| K01077 | alkaline phosphatase [EC:3.1.3.1] | 7 |
| K01113 | alkaline phosphatase D [EC:3.1.3.1] | 0 |
| K01307 | gamma-glutamyl hydrolase [EC:3.4.19.9] | 0 |
| K01495 | GTP cyclohydrolase IA [EC:3.5.4.16] | 7 |
| K01497 | GTP cyclohydrolase II [EC:3.5.4.25] | 7 |
| K01633 | 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] | 7 |
| K01664 | para-aminobenzoate synthetase component II [EC:2.6.1.85] | 7 |
| K01665 | para-aminobenzoate synthetase component I [EC:2.6.1.85] | 7 |
| K01724 | 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] | 0 |
| K01737 | 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] | 7 |
| K01930 | folylpolyglutamate synthase [EC:6.3.2.17] | 0 |
| K02619 | 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] | 7 |
| K03342 | para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] | 0 |
| K03635 | molybdopterin synthase catalytic subunit [EC:2.8.1.12] | 7 |
| K03637 | cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] | 7 |
| K03638 | molybdopterin adenylyltransferase [EC:2.7.7.75] | 0 |
| K03639 | GTP 3',8-cyclase [EC:4.1.99.22] | 7 |
| K03750 | molybdopterin molybdotransferase [EC:2.10.1.1] | 7 |
| K03752 | molybdenum cofactor guanylyltransferase [EC:2.7.7.77] | 1 |
| K03793 | pteridine reductase [EC:1.5.1.33] | 0 |
| K03831 | molybdopterin adenylyltransferase [EC:2.7.7.75] | 7 |
| K04119 | aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357] | 0 |
| K06879 | 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] | 7 |
| K06897 | 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] | 7 |
| K06920 | 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] | 7 |
| K06984 | beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] | 0 |
| K07141 | molybdenum cofactor cytidylyltransferase [EC:2.7.7.76] | 6 |
| K07142 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] | 0 |
| K07589 | D-erythro-7,8-dihydroneopterin triphosphate epimerase [EC:5.1.99.7] | 0 |
| K08310 | dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67] | 7 |
| K09007 | GTP cyclohydrolase IB [EC:3.5.4.16] | 0 |
| K09457 | 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] | 0 |
| K09739 | dihydroneopterin aldolase [EC:4.1.2.25] | 0 |
| K10026 | 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] | 7 |
| K11754 | dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] | 7 |
| K13818 | molybdopterin-guanine dinucleotide biosynthesis protein [EC:2.7.7.77] | 5 |
| K13938 | dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] | 0 |
| K13939 | dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15] | 0 |
| K13940 | dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3] | 0 |
| K13941 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15] | 0 |
| K13950 | para-aminobenzoate synthetase [EC:2.6.1.85] | 0 |
| K13998 | dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] | 0 |
| K14652 | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] | 0 |
| K15376 | gephyrin [EC:2.10.1.1 2.7.7.75] | 0 |
| K15631 | molybdenum cofactor sulfurtransferase [EC:2.8.1.9] | 0 |
| K15740 | tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33] | 0 |
| K17364 | dihydromethanopterin reductase [EC:1.5.1.47] | 0 |
| K17487 | 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase [EC:3.1.4.56] | 0 |
| K17488 | GTP cyclohydrolase IV [EC:3.5.4.39] | 0 |
| K17745 | sepiapterin reductase [EC:1.1.1.325] | 0 |
| K18482 | 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] | 0 |
| K18589 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 5 |
| K18590 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 4 |
| K18591 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 |
| K18824 | dihydropteroate synthase type 2 [EC:2.5.1.15] | 0 |
| K18825 | dihydropteroate synthase type 3 [EC:2.5.1.15] | 0 |
| K18853 | dihydromethanopterin reductase (acceptor) [EC:1.5.99.15] | 0 |
| K18974 | dihydropteroate synthase type 1 [EC:2.5.1.15] | 5 |
| K19643 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 |
| K19644 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 |
| K19645 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 |
| K19965 | dihydroneopterin triphosphate pyrophosphohydrolase [EC:3.6.1.67] | 0 |
| K20457 | dihydrofolate synthase [EC:6.3.2.12] | 0 |
| K20967 | GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC:4.1.99.22 4.6.1.17] | 0 |
| K21142 | MoaE-MoaD fusion protein [EC:2.8.1.12] | 0 |
| K22099 | dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] | 0 |
| K22100 | 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase [EC:4.2.1.160] | 0 |
| K22101 | dihydroneopterin triphosphate aldolase (PTPS-III) / 6-pyruvoyltetrahydropterin synthase [EC:4.1.2.60 4.2.3.12] | 0 |
| K22102 | dihydroneopterin phosphate aldolase [EC:4.1.2.59] | 0 |
| K22391 | GTP cyclohydrolase I [EC:3.5.4.16] | 0 |
| K24102 | dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15] | 0 |
| K25575 | 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) component II [EC:2.6.1.123] | 0 |
| K25578 | 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) component I [EC:2.6.1.123] | 0 |