M00126


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Kegg module M00126 is descriptive of Tetrahydrofolate biosynthesis, GTP => THF module, which is part of the Metabolism of cofactors and vitamins category and Cofactor and vitamin metabolism subcategory.

In General the list of Ko entries of M00126 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Tetrahydrofolate biosynthesis, GTP => THF module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00126 Kegg module

Id Description
K00287 dihydrofolate reductase [EC:1.5.1.3]
K00796 dihydropteroate synthase [EC:2.5.1.15]
K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
K01077 alkaline phosphatase [EC:3.1.3.1]
K01113 alkaline phosphatase D [EC:3.1.3.1]
K01495 GTP cyclohydrolase IA [EC:3.5.4.16]
K01633 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
K08310 dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]
K09007 GTP cyclohydrolase IB [EC:3.5.4.16]
K11754 dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K13939 dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
K13940 dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]
K13941 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
K13998 dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K19965 dihydroneopterin triphosphate pyrophosphohydrolase [EC:3.6.1.67]
K20457 dihydrofolate synthase [EC:6.3.2.12]
K22391 GTP cyclohydrolase I [EC:3.5.4.16]