M00841


Help

Kegg module M00841 is descriptive of Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF module, which is part of the Metabolism of cofactors and vitamins category and Cofactor and vitamin metabolism subcategory.

In General the list of Ko entries of M00841 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00841 Kegg module

Id Description
K01495 GTP cyclohydrolase IA [EC:3.5.4.16]
K11754 dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K13941 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
K13998 dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K22101 dihydroneopterin triphosphate aldolase (PTPS-III) / 6-pyruvoyltetrahydropterin synthase [EC:4.1.2.60 4.2.3.12]