Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of One carbon pool by folate Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the One carbon pool by folate pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00287 | dihydrofolate reductase [EC:1.5.1.3] | 1 | 8 |
| K00288 | methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] | 0 | 0 |
| K00289 | formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] | 0 | 0 |
| K00295 | methylenetetrahydrofolate dehydrogenase (NAD+) [EC:1.5.1.15] | 0 | 0 |
| K00297 | methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] | 1 | 7 |
| K00300 | methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+) [EC:1.5.1.5 1.5.1.-] | 0 | 0 |
| K00548 | 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] | 1 | 7 |
| K00560 | thymidylate synthase [EC:2.1.1.45] | 1 | 13 |
| K00600 | glycine hydroxymethyltransferase [EC:2.1.2.1] | 1 | 7 |
| K00601 | phosphoribosylglycinamide formyltransferase [EC:2.1.2.2] | 0 | 0 |
| K00602 | phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] | 1 | 7 |
| K00603 | glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] | 0 | 0 |
| K00604 | methionyl-tRNA formyltransferase [EC:2.1.2.9] | 1 | 7 |
| K00605 | glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] | 1 | 7 |
| K01433 | formyltetrahydrofolate deformylase [EC:3.5.1.10] | 1 | 7 |
| K01491 | methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] | 1 | 7 |
| K01492 | phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3] | 0 | 0 |
| K01500 | methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9] | 0 | 0 |
| K01746 | formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4] | 0 | 0 |
| K01934 | 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] | 1 | 7 |
| K01938 | formate--tetrahydrofolate ligase [EC:6.3.4.3] | 1 | 1 |
| K03465 | thymidylate synthase (FAD) [EC:2.1.1.148] | 0 | 0 |
| K11175 | phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] | 1 | 7 |
| K11787 | phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] | 0 | 0 |
| K13402 | monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3] | 0 | 0 |
| K13403 | methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9] | 0 | 0 |
| K13938 | dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] | 0 | 0 |
| K13990 | glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4] | 0 | 0 |
| K13998 | dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] | 0 | 0 |
| K18589 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 5 |
| K18590 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 4 |
| K18591 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 0 |
| K19643 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 0 |
| K19644 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 0 |
| K19645 | dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] | 0 | 0 |
| K24042 | methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54] | 0 | 0 |
| K25004 | methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53] | 0 | 0 |
| K25007 | methylenetetrahydrofolate reductase (NADH) small subunit | 0 | 0 |
| K25008 | ion-translocating oxidoreductase complex subunit C [EC:7.-.-.-] | 0 | 0 |
| K25009 | methylenetetrahydrofolate reductase [NAD(P)H] [EC:1.5.1.20] | 0 | 0 |
| K25221 | [methyl-Co(III) glycine betaine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.378] | 0 | 0 |
| K25915 | [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.385] | 0 | 0 |
| K26930 | [methyl-Co(III) quaternary-amine-specific corrinoid protein]---tetrahydrofolate methyltransferase [EC:2.1.1.389] | 0 | 0 |