K00560


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00560, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 13 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00560
KO K00560
Description thymidylate synthase [EC:2.1.1.45]

KO part of 5 pathways

Pyrimidine metabolism
One carbon pool by folate
Metabolic pathways
Nucleotide metabolism
Antifolate resistance

KO part of 1 modules

M00938 Pyrimidine metabolism Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Occurence in the database

K00560 is associated with 13 different proteins (see tab "Protein list" and "Profile")
The 13 proteins are classified into 2 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_281 PMI_RS11465 2525410 2526261 -1 thymidylate synthase Proteus mirabilis HI4320
1 group_281 FBDBKF_06190 65824 66759 1 thyA thymidylate synthase Morganella morganii S1
2 group_281 EHELCC_09235 66396 67331 1 thyA thymidylate synthase Morganella morganii S2
3 group_281 NLDBIP_09615 66396 67331 1 thyA thymidylate synthase Morganella morganii S4
4 group_281 LHKJJB_08140 149907 150842 -1 thyA thymidylate synthase Morganella morganii S3
5 group_281 HKOGLL_07690 149907 150842 -1 thyA thymidylate synthase Morganella morganii S5
6 group_3434 FBDBKF_14460 90300 91283 1 Thymidylate synthase Morganella morganii S1
7 group_3434 EHELCC_07820 25702 26685 -1 Thymidylate synthase Morganella morganii S2
8 group_3434 NLDBIP_08145 25702 26685 -1 Thymidylate synthase Morganella morganii S4
9 group_3434 LHKJJB_06120 230474 231457 1 Thymidylate synthase Morganella morganii S3
10 group_3434 HKOGLL_04795 10293 11276 -1 Thymidylate synthase Morganella morganii S5
11 group_281 F4V73_RS17895 20229 21344 -1 thymidylate synthase Morganella psychrotolerans
12 group_281 F4V73_RS15725 147750 148544 1 thyA thymidylate synthase Morganella psychrotolerans