K00560


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00560
Protein list: lists the 8 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00560
KO K00560
Description thymidylate synthase [EC:2.1.1.45]

KO part of 6 pathways

Pyrimidine metabolism
One carbon pool by folate
Metabolic pathways
Nucleotide metabolism
Antifolate resistance
Folate transport and metabolism

KO part of 1 modules

M00938 Pyrimidine metabolism Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Occurence in the database

K00560 is associated with 8 different proteins
The 8 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_256 FBDBKF_06190 65824 66759 1 thyA thymidylate synthase Morganella morganii S1
1 group_256 EHELCC_09235 66396 67331 1 thyA thymidylate synthase Morganella morganii S2
2 group_256 NLDBIP_09615 66396 67331 1 thyA thymidylate synthase Morganella morganii S4
3 group_256 LHKJJB_08140 149907 150842 -1 thyA thymidylate synthase Morganella morganii S3
4 group_256 HKOGLL_07690 149907 150842 -1 thyA thymidylate synthase Morganella morganii S5
5 group_256 F4V73_RS15725 147750 148544 1 thyA thymidylate synthase Morganella psychrotolerans
6 group_256 F4V73_RS17895 20229 21344 -1 thymidylate synthase Morganella psychrotolerans
7 group_256 PMI_RS11465 2525410 2526261 -1 thymidylate synthase Proteus mirabilis HI4320