Homologs in group_1913

Help

6 homologs were identified in 6 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_14250 FBDBKF_14250 91.2 Morganella morganii S1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
EHELCC_08030 EHELCC_08030 91.2 Morganella morganii S2 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
NLDBIP_08355 NLDBIP_08355 91.2 Morganella morganii S4 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
LHKJJB_05910 LHKJJB_05910 91.2 Morganella morganii S3 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
HKOGLL_05005 HKOGLL_05005 91.2 Morganella morganii S5 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase
PMI_RS08760 PMI_RS08760 64.1 Proteus mirabilis HI4320 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase

Distribution of the homologs in the orthogroup group_1913

Help

Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

Download SVG

Phylogeny of the RefSeq best hits of group_1913

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P08192 4.92e-156 451 57 2 422 1 folC Dihydrofolate synthase/folylpolyglutamate synthase Escherichia coli (strain K12)
P43775 4.73e-123 367 46 5 434 3 folC Dihydrofolate synthase/folylpolyglutamate synthase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q8K9X3 1.23e-101 311 40 7 411 3 folC Dihydrofolate synthase/folylpolyglutamate synthase Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
P57265 2.99e-100 308 41 6 414 3 folC Dihydrofolate synthase/folylpolyglutamate synthase Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Q89AT2 3.23e-94 293 37 4 426 3 folC Dihydrofolate synthase/folylpolyglutamate synthase Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Q9HS44 5.05e-44 167 33 12 408 3 folP Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
P15925 1.22e-37 145 29 9 393 1 fpgS Folylpolyglutamate synthase Lacticaseibacillus casei
Q05865 1.62e-35 139 27 8 409 3 folC Dihydrofolate synthase/folylpolyglutamate synthase Bacillus subtilis (strain 168)
I6Y0R5 5.27e-33 133 32 10 365 1 folC Dihydrofolate synthase/folylpolyglutamate synthase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
D4GW05 1.83e-31 130 29 12 428 3 folCP Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
A6H751 6.76e-30 125 30 16 386 2 FPGS Folylpolyglutamate synthase, mitochondrial Bos taurus
Q05932 8.68e-30 125 29 15 390 1 FPGS Folylpolyglutamate synthase, mitochondrial Homo sapiens
Q8W035 8.96e-30 124 35 11 290 1 FPGS3 Folylpolyglutamate synthase Arabidopsis thaliana
Q09509 6.61e-29 122 30 9 316 3 F25B5.6 Putative folylpolyglutamate synthase Caenorhabditis elegans
Q9UTD0 8.29e-29 120 28 7 346 3 fol3 Probable dihydrofolate synthetase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q924L9 9.8e-29 122 29 15 383 2 FPGS Folylpolyglutamate synthase, mitochondrial Cricetulus griseus
F4JYE9 6.16e-28 119 30 9 353 1 DHFS Dihydrofolate synthetase Arabidopsis thaliana
P48760 2.75e-27 117 29 13 378 1 Fpgs Folylpolyglutamate synthase, mitochondrial Mus musculus
F4J2K2 1.27e-26 115 37 4 200 1 FPGS2 Folylpolyglutamate synthase Arabidopsis thaliana
Q54CY5 1.01e-25 113 31 4 220 3 folC Putative folylpolyglutamate synthase Dictyostelium discoideum
F4K2A1 2.29e-25 112 32 11 336 1 FPGS1 Folylpolyglutamate synthase Arabidopsis thaliana
O74742 5.84e-25 110 30 12 316 2 met7 Probable folylpolyglutamate synthase Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q12676 1.24e-24 108 25 15 436 1 FOL3 Dihydrofolate synthetase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q9Y893 3.05e-23 105 27 11 292 3 MET7 Folylpolyglutamate synthase Candida albicans
E7NMM0 2.04e-19 94 27 9 294 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain FostersO)
B5VSC3 2.21e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain AWRI1631)
E7KIA3 2.31e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain AWRI796)
E7QKX4 2.33e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain Zymaflore VL3)
Q08645 2.33e-19 94 27 10 307 1 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E7KUJ4 2.33e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain Lalvin QA23)
C8ZGZ3 2.33e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)
A6ZP80 2.33e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain YJM789)
B3LJR0 2.33e-19 94 27 10 307 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain RM11-1a)
E7Q9C7 4.71e-19 92 32 5 192 3 MET7 Folylpolyglutamate synthase Saccharomyces cerevisiae (strain FostersB)
O13492 1.1e-16 85 32 6 183 1 met-6 Folylpolyglutamate synthase Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q929X9 2.92e-06 53 21 14 404 3 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Q8Y5L9 0.00017 47 20 15 411 3 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Q71XX5 0.000173 47 20 15 411 3 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase Listeria monocytogenes serotype 4b (strain F2365)

  • Number of RefSeq hits:

General

Source Morganella psychrotolerans
Locus tag F4V73_RS02660
Feature type CDS
Gene folC
Product bifunctional tetrahydrofolate synthase/dihydrofolate synthase
Location 559884 - 561185 (strand: 1)
Length 1302 (nucleotides) / 433 (amino acids)

Contig

Accession term accessions NZ_VXKB01000001 accessions NZ_VXKB01000000 Name: value, dtype: object
Length 2012992 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_1913
Orthogroup size 7
N. genomes 7

Actions

Genomic region

Domains

PF02875 Mur ligase, glutamate ligase domain
PF08245 Mur ligase middle domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0285 Coenzyme transport and metabolism (H) H Folylpolyglutamate synthase/Dihydropteroate synthase

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K11754 dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] Folate biosynthesis
Metabolic pathways
Biosynthesis of cofactors		 Tetrahydrofolate biosynthesis, GTP => THF
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF

Protein Sequence

MSDKQEKLTAASSLMAWLSYLGDLHSQVIDMGLERVGAVADIMNLRYPAPKVITVSGTNGKGTTCHTLESVFLAAGLRVGVYSSPHLINYTERVRIQGENPSEADFCRVFADIDAQRGDITLTYFEAGTLAALQLFREANLDVVILEVGLGGRLDATNIVDSHITAITSIALDHTDWLGADREHIAREKAGIFRPHCVAVIGEPDAPYTIADVANKLETSLFCRVDDWSYKEQGDHWTWQCEDETLTNLPLPNVPLANAATALAVIHNLRLVKDKTGRAINREAIDAGLRQAQLPGRFQIVSQHPLTVLDVAHNPHAAGYLVSKLAQLPRTADSRVRAVVGMLGDKDIKGTLAVLSEQVTDWYFAPLTELRGAPAEQLAEHIPGAQLFADVESAWAQACLDADAGDIIVVCGSFHTVAHVMDVLSSEEGAGGQ

Flanking regions ( +/- flanking 50bp)

ATTTTCTGAAACAACAGCTGACGTTAAAAAACGAGATGTCAAAAAACGCGATGTCTGATAAGCAAGAGAAACTGACAGCCGCGTCATCATTGATGGCGTGGCTTTCTTATCTGGGTGACCTGCATTCGCAGGTTATTGATATGGGACTGGAACGCGTCGGTGCGGTGGCAGATATCATGAATCTGCGCTATCCCGCCCCGAAAGTTATTACCGTCTCCGGAACCAACGGCAAAGGCACCACCTGCCATACGCTTGAGTCTGTCTTTCTCGCGGCCGGGTTGCGGGTCGGGGTGTACAGTTCCCCGCATCTGATCAATTACACTGAACGCGTCCGTATTCAGGGGGAAAACCCTTCTGAAGCTGATTTCTGCCGTGTTTTCGCTGATATTGACGCGCAGCGCGGCGATATCACGCTGACCTATTTTGAAGCGGGCACGCTGGCGGCATTGCAGTTATTCCGCGAAGCCAATCTTGATGTCGTTATCCTCGAAGTCGGTCTTGGCGGGCGTCTGGATGCCACCAATATTGTGGATTCGCATATTACCGCGATCACCAGTATCGCGCTGGATCATACCGACTGGCTGGGTGCTGACCGTGAACATATCGCCCGTGAAAAAGCCGGTATTTTTCGTCCGCACTGTGTGGCGGTGATTGGCGAGCCTGATGCACCGTACACTATTGCCGATGTGGCAAACAAGCTGGAAACATCACTGTTCTGCCGTGTGGATGACTGGTCGTATAAAGAACAGGGCGACCACTGGACATGGCAGTGTGAGGATGAAACCCTGACAAATCTGCCGTTGCCGAATGTCCCTCTGGCAAATGCCGCAACCGCACTGGCGGTTATTCATAACCTGCGTCTGGTGAAAGATAAAACCGGGCGGGCAATTAATCGTGAAGCGATTGATGCCGGTCTGCGTCAGGCACAACTGCCCGGGCGCTTCCAGATTGTGTCGCAGCACCCGCTGACGGTGCTGGATGTGGCGCACAATCCGCATGCGGCAGGATATCTGGTTTCAAAACTGGCACAATTACCACGCACCGCAGACTCGCGTGTCCGTGCGGTGGTGGGGATGCTGGGAGATAAAGATATTAAAGGCACCCTGGCGGTGCTGAGTGAGCAGGTGACAGACTGGTATTTTGCCCCGCTGACAGAGTTACGCGGCGCACCGGCAGAACAGCTTGCTGAGCATATTCCGGGCGCACAATTGTTTGCTGATGTGGAAAGCGCATGGGCACAGGCGTGCCTGGATGCGGATGCCGGTGACATCATTGTTGTGTGCGGATCATTCCATACTGTCGCGCATGTTATGGACGTTTTATCATCAGAGGAAGGTGCGGGTGGCCAGTAAATTTCAGAATCGCTTAGTCGGAACGATTATCCTGGTTGCGGTGGGCGTGA