PF08245

Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Pfam domain PF08245
Protein list: lists the 42 occurences of the Pfam domain within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Pfam domain of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Pfam domain has been clustered.
Orthogroups are shown in red if they are annotated with that particular Pfam domain in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Pfam domain prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Pfam domain.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Pfam domain prediction.

Description

External link PF08245
Description Mur ligase middle domain

Occurence in the database

PF08245 is associated with 42 different proteins
The 42 proteins are classified into 6 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_925 FBDBKF_04330 54058 55479 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella morganii S1
1 group_928 FBDBKF_04345 57810 59126 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella morganii S1
2 group_930 FBDBKF_04355 60205 61578 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase Morganella morganii S1
3 group_931 FBDBKF_04360 61575 63062 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-di aminopimelate ligase Morganella morganii S1
4 group_1443 FBDBKF_08565 95680 97032 1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase Morganella morganii S1
5 group_1951 FBDBKF_14250 49351 50703 -1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella morganii S1
6 group_925 EHELCC_05620 113515 114936 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella morganii S2
7 group_928 EHELCC_05635 117267 118583 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella morganii S2
8 group_930 EHELCC_05645 119662 121035 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase Morganella morganii S2
9 group_931 EHELCC_05650 121032 122519 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-di aminopimelate ligase Morganella morganii S2
10 group_1951 EHELCC_08030 66282 67634 1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella morganii S2
11 group_1443 EHELCC_12960 66693 68045 -1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase Morganella morganii S2
12 group_925 NLDBIP_05940 154580 156001 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella morganii S4
13 group_928 NLDBIP_05955 158332 159648 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella morganii S4
14 group_930 NLDBIP_05965 160727 162100 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase Morganella morganii S4
15 group_931 NLDBIP_05970 162097 163584 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-di aminopimelate ligase Morganella morganii S4
16 group_1951 NLDBIP_08355 66282 67634 1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella morganii S4
17 group_1443 NLDBIP_13300 66693 68045 -1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase Morganella morganii S4
18 group_925 LHKJJB_02820 132104 133525 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella morganii S3
19 group_928 LHKJJB_02835 135856 137172 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella morganii S3
20 group_930 LHKJJB_02845 138251 139624 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase Morganella morganii S3
21 group_931 LHKJJB_02850 139621 141108 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-di aminopimelate ligase Morganella morganii S3
22 group_1951 LHKJJB_05910 189525 190877 -1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella morganii S3
23 group_1443 LHKJJB_13255 94398 95750 1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase Morganella morganii S3
24 group_1951 HKOGLL_05005 50873 52225 1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella morganii S5
25 group_925 HKOGLL_06295 53968 55389 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella morganii S5
26 group_928 HKOGLL_06310 57720 59036 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella morganii S5
27 group_930 HKOGLL_06320 60115 61488 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase Morganella morganii S5
28 group_931 HKOGLL_06325 61485 62972 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-di aminopimelate ligase Morganella morganii S5
29 group_1443 HKOGLL_11775 66693 68045 -1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase Morganella morganii S5
30 group_1951 F4V73_RS02660 559884 561185 1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Morganella psychrotolerans
31 group_925 F4V73_RS08775 1815178 1816644 -1 murC UDP-N-acetylmuramate--L-alanine ligase Morganella psychrotolerans
32 group_928 F4V73_RS08790 1818930 1820246 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Morganella psychrotolerans
33 group_930 F4V73_RS08800 1821325 1822698 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase Morganella psychrotolerans
34 group_931 F4V73_RS08805 1822695 1824182 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase Morganella psychrotolerans
35 group_1443 F4V73_RS09790 62130 63482 1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase Morganella psychrotolerans
36 group_1951 PMI_RS08760 1915680 1916978 -1 folC bifunctional tetrahydrofolate synthase/dihydrofolate synthase Proteus mirabilis HI4320
37 group_925 PMI_RS10195 2231761 2233224 -1 murC UDP-N-acetylmuramate--L-alanine ligase Proteus mirabilis HI4320
38 group_928 PMI_RS10210 2235538 2236848 -1 murD UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Proteus mirabilis HI4320
39 group_930 PMI_RS10220 2237926 2239308 -1 murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase Proteus mirabilis HI4320
40 group_931 PMI_RS10225 2239305 2240792 -1 murE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase Proteus mirabilis HI4320
41 group_1443 PMI_RS16915 3725946 3727325 1 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase Proteus mirabilis HI4320