Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Antifolate resistance Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Antifolate resistance pathway
| KO | Description | All occurrences |
|---|---|---|
| K00287 | dihydrofolate reductase [EC:1.5.1.3] | 8 |
| K00458 | arachidonate 12-lipoxygenase [EC:1.13.11.31] | 0 |
| K00560 | thymidylate synthase [EC:2.1.1.45] | 13 |
| K00600 | glycine hydroxymethyltransferase [EC:2.1.2.1] | 7 |
| K00602 | phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] | 7 |
| K01307 | gamma-glutamyl hydrolase [EC:3.4.19.9] | 0 |
| K01930 | folylpolyglutamate synthase [EC:6.3.2.17] | 0 |
| K02580 | nuclear factor NF-kappa-B p105 subunit | 0 |
| K03156 | tumor necrosis factor superfamily, member 2 | 0 |
| K04467 | inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] | 0 |
| K04519 | interleukin 1 beta | 0 |
| K04735 | transcription factor p65 | 0 |
| K05405 | interleukin 6 | 0 |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] | 0 |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 | 0 |
| K05667 | ATP-binding cassette, subfamily C (CFTR/MRP), member 3 | 0 |
| K05668 | ATP-binding cassette, subfamily C (CFTR/MRP), member 5 | 0 |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 | 0 |
| K05681 | ATP-binding cassette, subfamily G (WHITE), member 2 | 0 |
| K07209 | inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] | 0 |
| K07210 | inhibitor of nuclear factor kappa-B kinase subunit gamma | 0 |
| K11787 | phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] | 0 |
| K13649 | folate receptor | 0 |
| K14609 | solute carrier family 19 (folate transporter), member 1 | 0 |
| K14613 | MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1 | 0 |
| K25004 | methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53] | 0 |