Homologs in group_166

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9 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_15970 FBDBKF_15970 42.0 Morganella morganii S1 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
EHELCC_18575 EHELCC_18575 42.0 Morganella morganii S2 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
NLDBIP_17405 NLDBIP_17405 42.0 Morganella morganii S4 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
LHKJJB_17255 LHKJJB_17255 42.0 Morganella morganii S3 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
HKOGLL_17140 HKOGLL_17140 42.0 Morganella morganii S5 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
F4V73_RS16340 F4V73_RS16340 42.3 Morganella psychrotolerans - efflux RND transporter periplasmic adaptor subunit
F4V73_RS17015 F4V73_RS17015 27.7 Morganella psychrotolerans - efflux RND transporter periplasmic adaptor subunit
PMI_RS00640 PMI_RS00640 41.8 Proteus mirabilis HI4320 - efflux RND transporter periplasmic adaptor subunit
PMI_RS13340 PMI_RS13340 23.8 Proteus mirabilis HI4320 - efflux RND transporter periplasmic adaptor subunit

Distribution of the homologs in the orthogroup group_166

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_166

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
O31099 3.98e-128 376 50 2 361 2 srpA Solvent efflux pump periplasmic linker SrpA Pseudomonas putida
Q93PU5 4.72e-128 376 50 2 361 2 ttgG Toluene efflux pump periplasmic linker protein TtgG Pseudomonas putida (strain DOT-T1E)
Q9KWV5 1.68e-125 369 49 2 361 2 ttgD Toluene efflux pump periplasmic linker protein TtgD Pseudomonas putida (strain DOT-T1E)
Q849Q9 1.68e-125 369 49 2 361 3 sepA Probable efflux pump periplasmic linker protein SepA Pseudomonas putida (strain ATCC 700007 / DSM 6899 / JCM 31910 / BCRC 17059 / LMG 24140 / F1)
P52477 5.56e-111 332 45 2 366 1 mexA Multidrug resistance protein MexA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q88N30 1.61e-104 316 46 2 357 1 ttgA Probable efflux pump periplasmic linker TtgA Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
P0C069 1.61e-104 316 46 2 357 1 mepA Multidrug/solvent efflux pump periplasmic linker protein MepA Pseudomonas putida
Q9WWZ9 5.21e-104 315 45 2 357 2 ttgA Toluene efflux pump periplasmic linker protein TtgA Pseudomonas putida (strain DOT-T1E)
Q9KJC3 2.94e-100 304 46 2 345 2 arpA Antibiotic efflux pump periplasmic linker protein ArpA Pseudomonas putida
P24180 1.4e-96 295 43 4 373 1 acrE Multidrug export protein AcrE Escherichia coli (strain K12)
P0AE06 9.42e-96 294 42 5 381 1 acrA Multidrug efflux pump subunit AcrA Escherichia coli (strain K12)
P0AE07 9.42e-96 294 42 5 381 3 acrA Multidrug efflux pump subunit AcrA Escherichia coli O157:H7
Q8X4L0 3.74e-90 279 39 2 365 3 mdtE Multidrug resistance protein MdtE Escherichia coli O157:H7
P37636 5.95e-90 278 39 2 365 1 mdtE Multidrug resistance protein MdtE Escherichia coli (strain K12)
Q8CVL1 8.32e-90 278 39 2 365 3 mdtE Multidrug resistance protein MdtE Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P43505 5.72e-74 238 40 5 343 3 mtrC Membrane fusion protein MtrC Neisseria gonorrhoeae
Q8G2M7 3.73e-52 181 33 5 334 1 bepD Efflux pump periplasmic linker BepD Brucella suis biovar 1 (strain 1330)
Q8FWV8 1.57e-49 174 33 8 363 1 bepF Efflux pump periplasmic linker BepF Brucella suis biovar 1 (strain 1330)
B4EY99 1.2e-37 143 29 4 343 3 mdtA Multidrug resistance protein MdtA Proteus mirabilis (strain HI4320)
D4I6V2 4.55e-34 133 31 6 312 3 mdtA Multidrug resistance protein MdtA Erwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3)
F2EYD8 8.22e-34 132 29 7 355 3 mdtA Multidrug resistance protein MdtA Pantoea ananatis (strain AJ13355)
Q7N3E3 1.29e-33 132 27 5 340 3 mdtA Multidrug resistance protein MdtA Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
A4TMR2 5.02e-33 131 32 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pestis (strain Pestoides F)
Q1CK59 5.02e-33 131 32 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pestis bv. Antiqua (strain Nepal516)
Q8ZCW1 5.02e-33 131 32 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pestis
Q1C5M1 5.02e-33 131 32 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pestis bv. Antiqua (strain Antiqua)
A7FG18 6.02e-33 131 32 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
B1JSD5 1.36e-32 130 31 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Q668C7 1.6e-32 130 31 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype I (strain IP32953)
B2K9L9 1.6e-32 130 31 6 310 3 mdtA Multidrug resistance protein MdtA Yersinia pseudotuberculosis serotype IB (strain PB1/+)
A1JKX1 2.35e-32 129 30 6 341 3 mdtA Multidrug resistance protein MdtA Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
C5BHN6 8.51e-32 127 28 7 321 3 mdtA Multidrug resistance protein MdtA Edwardsiella ictaluri (strain 93-146)
A6TBH3 1.71e-31 126 30 8 346 3 mdtA Multidrug resistance protein MdtA Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
C9XVZ5 1.36e-28 118 28 8 338 3 mdtA Multidrug resistance protein MdtA Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)
A4WCC0 1.73e-28 118 28 7 321 3 mdtA Multidrug resistance protein MdtA Enterobacter sp. (strain 638)
D3V7P2 6.69e-28 116 28 7 342 3 mdtA Multidrug resistance protein MdtA Xenorhabdus bovienii (strain SS-2004)
Q83KI5 1.93e-27 114 27 7 322 3 mdtA Putative multidrug resistance protein MdtA Shigella flexneri
A7ZNP7 6.38e-27 114 26 7 353 3 mdtA Multidrug resistance protein MdtA Escherichia coli O139:H28 (strain E24377A / ETEC)
B7MWY7 6.83e-27 114 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O81 (strain ED1a)
Q6D2B2 7.33e-27 113 30 7 314 3 mdtA Multidrug resistance protein MdtA Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
B2TYA9 7.4e-27 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
B5YUD2 7.4e-27 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7 (strain EC4115 / EHEC)
Q8X7J5 7.4e-27 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O157:H7
B7M457 7.47e-27 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O8 (strain IAI1)
Q0TG16 7.85e-27 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:K15:H31 (strain 536 / UPEC)
C6DBC6 8.54e-27 113 29 7 314 3 mdtA Multidrug resistance protein MdtA Pectobacterium carotovorum subsp. carotovorum (strain PC1)
B7LV38 9.56e-27 113 26 8 349 3 mdtA Multidrug resistance protein MdtA Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
B7L9U7 9.66e-27 113 26 6 316 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain 55989 / EAEC)
P76397 1.19e-26 113 26 7 349 2 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12)
A8A1U6 1.19e-26 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O9:H4 (strain HS)
B1X7H0 1.19e-26 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / DH10B)
C4ZSG2 1.19e-26 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain K12 / MC4100 / BW2952)
B7UTB2 1.19e-26 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O127:H6 (strain E2348/69 / EPEC)
B7NQB2 1.24e-26 113 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O7:K1 (strain IAI39 / ExPEC)
B1LNW7 1.45e-26 112 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli (strain SMS-3-5 / SECEC)
Q8CVX8 1.89e-26 112 26 7 347 3 mdtA Multidrug resistance protein MdtA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
B7NCB0 2.05e-26 112 26 7 349 3 mdtA Multidrug resistance protein MdtA Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
B7ME86 2.15e-26 112 25 7 353 3 mdtA Multidrug resistance protein MdtA Escherichia coli O45:K1 (strain S88 / ExPEC)
Q8ZNQ3 3.57e-25 108 28 6 314 3 mdtA Multidrug resistance protein MdtA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8Z5F8 4.05e-25 108 28 7 322 3 mdtA Multidrug resistance protein MdtA Salmonella typhi
C0Q1F4 4.05e-25 108 28 7 322 3 mdtA Multidrug resistance protein MdtA Salmonella paratyphi C (strain RKS4594)
B4T9U0 4.21e-25 108 28 7 322 3 mdtA Multidrug resistance protein MdtA Salmonella heidelberg (strain SL476)
D2BTK6 3.01e-20 95 27 9 311 3 mdtA Multidrug resistance protein MdtA Dickeya zeae (strain Ech586)
Q57500 4.24e-14 76 25 5 241 3 HI_0894 Uncharacterized protein HI_0894 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
P58411 3.83e-07 55 24 7 269 3 macA Macrolide export protein MacA Yersinia pestis
P75830 1.18e-05 50 27 3 155 1 macA Macrolide export protein MacA Escherichia coli (strain K12)
B4TX73 0.000544 45 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella schwarzengrund (strain CVM19633)
B5F7M5 0.000544 45 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella agona (strain SL483)
Q7CPM8 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8XF83 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella typhi
B5BGR9 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi A (strain AKU_12601)
C0PZR0 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi C (strain RKS4594)
A9N863 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Q5PJT8 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi A (strain ATCC 9150 / SARB42)
B4T775 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella newport (strain SL254)
B4TJT9 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella heidelberg (strain SL476)
B5R1A8 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella enteritidis PT4 (strain P125109)
B5FIU3 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella dublin (strain CT_02021853)
Q57JA3 0.00077 44 28 3 135 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella choleraesuis (strain SC-B67)
A7MJB1 0.000791 44 27 4 149 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Cronobacter sakazakii (strain ATCC BAA-894)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS17905
Feature type CDS
Gene -
Product efflux RND transporter periplasmic adaptor subunit
Location 3933031 - 3934170 (strand: 1)
Length 1140 (nucleotides) / 379 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_166
Orthogroup size 10
N. genomes 7

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Genomic region

Domains

PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG0845 Cell wall/membrane/envelope biogenesis (M)
Defense mechanisms (V)		 MV Multidrug efflux pump subunit AcrA (membrane-fusion protein)

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K03585 membrane fusion protein, multidrug efflux system beta-Lactam resistance
Cationic antimicrobial peptide (CAMP) resistance		 Multidrug resistance, efflux pump MexAB-OprM

Protein Sequence

MKKTKHLFKTKGCNIPFTSVMMVSFVLMGCNDQSTQPTKPAIPEVGVYTVKEEILPLTVDLPARTASYRVSQVRPQVDGILEKRLFTEGSDVKKDQPLYQIDKKPYETQVAKAQAAYDNVKKLAARYKSLRATNAISQQEYDDVVSRLDQAKADLNQAKINLGYTQVLSPISGKISRSFVSEGALVSSGQSQPLATITQLDPIYVDITQPITNQLKLKSLIQQGVVTDSEDKMDVTLFLEDGSQYPYTGTLSFSEVQVEPSTGSVTLRAKFPNPQHQLLPGMYTKARIMQGTQEKAIVVPQQAITFDARGKSITYIVDQQQVLQARDVEILKPQGNGWIIKQGLQAGDRIMTEGHHRAKPGVKVNAVPANNISLKTTLE

Flanking regions ( +/- flanking 50bp)

ATTCGCATAGGGAGTACGGTATTTTTTTTATCAGCACAATTCCACTAACTATGAAAAAAACAAAACATTTATTTAAAACAAAGGGTTGTAATATTCCTTTTACTTCTGTGATGATGGTAAGTTTTGTCTTAATGGGCTGTAACGATCAATCGACTCAGCCAACCAAGCCTGCTATCCCAGAAGTGGGAGTCTATACTGTCAAAGAGGAAATTCTTCCATTAACGGTCGATTTGCCAGCAAGAACGGCATCTTATCGTGTCTCACAGGTGCGCCCACAAGTCGATGGTATTTTAGAAAAACGTCTATTTACTGAAGGTAGTGATGTTAAAAAAGATCAACCACTGTATCAAATAGATAAAAAACCTTACGAAACTCAGGTAGCTAAAGCGCAAGCGGCTTACGATAATGTGAAAAAATTAGCTGCCCGTTATAAATCTTTACGTGCCACTAATGCCATTAGTCAGCAAGAATATGACGATGTAGTATCACGCCTTGATCAAGCTAAAGCCGATTTAAATCAAGCAAAGATTAACCTTGGCTATACCCAAGTTTTATCACCTATTAGTGGCAAAATCAGTCGCTCTTTTGTTAGTGAAGGGGCATTAGTGAGTAGTGGACAAAGCCAGCCATTAGCGACCATCACACAGCTTGATCCTATCTATGTGGATATTACTCAACCTATTACTAACCAACTGAAATTAAAGTCACTGATCCAACAAGGTGTCGTCACTGATAGTGAAGATAAAATGGATGTGACGCTGTTTTTAGAAGATGGCTCTCAGTACCCTTATACCGGTACATTAAGTTTTTCCGAAGTCCAAGTTGAGCCAAGTACAGGCTCAGTGACATTACGCGCCAAATTCCCTAATCCACAGCACCAATTATTACCAGGAATGTATACCAAAGCTCGCATTATGCAAGGAACTCAAGAGAAAGCGATTGTTGTGCCACAACAAGCGATTACCTTTGATGCCCGTGGTAAATCCATCACATATATCGTTGATCAACAACAAGTATTACAAGCAAGAGATGTTGAAATATTAAAACCACAAGGTAATGGATGGATCATAAAACAGGGATTACAAGCTGGCGATAGGATCATGACAGAAGGTCATCATCGTGCAAAACCGGGCGTAAAAGTCAATGCGGTTCCTGCTAACAACATTTCATTAAAGACCACCTTAGAGTAAGTCTTCATTTAGGTAATACATTATTATGTCTCGATTTTTTATTAATCGGC