Orthogroup:group_166


Homologs in group_166

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10 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Source Gene Product
FBDBKF_15970 FBDBKF_15970 Morganella morganii S1 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
EHELCC_18575 EHELCC_18575 Morganella morganii S2 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
NLDBIP_17405 NLDBIP_17405 Morganella morganii S4 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
LHKJJB_17255 LHKJJB_17255 Morganella morganii S3 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
HKOGLL_17140 HKOGLL_17140 Morganella morganii S5 acrA Multidrug efflux pump subunit AcrA (membrane-fusion protein)
F4V73_RS16340 F4V73_RS16340 Morganella psychrotolerans - efflux RND transporter periplasmic adaptor subunit
F4V73_RS17015 F4V73_RS17015 Morganella psychrotolerans - efflux RND transporter periplasmic adaptor subunit
PMI_RS00640 PMI_RS00640 Proteus mirabilis HI4320 - efflux RND transporter periplasmic adaptor subunit
PMI_RS13340 PMI_RS13340 Proteus mirabilis HI4320 - efflux RND transporter periplasmic adaptor subunit
PMI_RS17905 PMI_RS17905 Proteus mirabilis HI4320 - efflux RND transporter periplasmic adaptor subunit

Distribution of group_166 homologs

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Number of homologs in each genome (first column and blue bar chart)

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Phylogeny of group_166 (midpoint rooted)


Phylogeny of the RefSeq best hits of group_166

Orthogroup content: 10 members

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This page summarizes the annotation of all members of the orthologous group group_166.
Gene name(s), gene product(s), a summary of protein lenght, and annotations (when available) are provided. Additionally, the number of times (occurence) an annotation is observed in the orthogroup is reported for each annotation.

Orthologs were identified with OrthoFinder. The annotation of orthologous proteins can differ depending the approach used to annotate the source genomes. Automated annotations are also subject to errors. Spurious clustering of non-orthologous proteins can also happen. This page allows to check for eventual inconsistencies.

Gene

# Gene name Occurence
1 acrA 5
2 - 5

Product

# Product Occurence
1 Multidrug efflux pump subunit AcrA (membrane-fusion protein) 5
2 efflux RND transporter periplasmic adaptor subunit 5

COG entry Annotation(s)

ID Occurences Function(s) cat. Function(s) descr. Description
COG0845 10 MV Cell wall/membrane/envelope biogenesis (M)
Defense mechanisms (V)		 Multidrug efflux pump subunit AcrA (membrane-fusion protein)

Kegg Ortholog Annotation(s)

KO Occurences Description Pathways Modules
K03585 8 membrane fusion protein, multidrug efflux system beta-Lactam resistance
Cationic antimicrobial peptide (CAMP) resistance		 Multidrug resistance, efflux pump MexAB-OprM
K18306 1 membrane fusion protein, multidrug efflux system Quorum sensing -
K19595 1 membrane fusion protein, gold/copper resistance efflux system - Multidrug resistance, efflux pump MexPQ-OpmE

Pfam domain Annotation(s)

Domain ID Occurences Description
PF00529 7 Cation efflux system protein CusB domain 1
PF16576 10 Barrel-sandwich domain of CusB or HlyD membrane-fusion

Virulence factor Annotation(s)

VF gene ID Occurences Protein VF ID Category
VFG049129 7 acriflavine resistance protein A VF0568 Antimicrobial activity/Competitive advantage

Annotations of the 191 SwissProt hits

Annotation Number of occurrences
Antibiotic efflux pump periplasmic linker protein ArpA 1
Cation efflux system protein CusB 3
Cation efflux system protein CzcB 1
Cobalt-zinc-cadmium resistance protein CzcB 1
Colistin resistance protein EmrA 1
Efflux pump periplasmic linker BepD 1
Efflux pump periplasmic linker BepF 1
Inner membrane protein YibH 2
Macrolide export protein MacA 4
Membrane fusion protein MtrC 1
Multidrug efflux pump subunit AcrA 2
Multidrug export protein AcrE 1
Multidrug resistance protein MdtA 44
Multidrug resistance protein MdtE 3
Multidrug resistance protein MdtN 4
Multidrug resistance protein MexA 1
Multidrug/solvent efflux pump periplasmic linker protein MepA 1
Nickel and cobalt resistance protein CnrB 1
Nickel-cobalt-cadmium resistance protein NccB 1
Nodulation protein NolF 1
Probable efflux pump periplasmic linker TtgA 1
Probable efflux pump periplasmic linker protein SepA 1
Putative efflux system component YknX 1
Putative membrane fusion protein SilB 1
Putative multidrug resistance protein MdtA 1
Pyoverdine export membrane fusion protein PvdR 2
Solvent efflux pump periplasmic linker SrpA 1
Toluene efflux pump periplasmic linker protein TtgA 1
Toluene efflux pump periplasmic linker protein TtgD 1
Toluene efflux pump periplasmic linker protein TtgG 1
UPF0194 membrane protein CKO_02332 1
UPF0194 membrane protein Ent638_1286 1
UPF0194 membrane protein YbhG 42
Uncharacterized protein HI_0894 1
Uncharacterized protein YdhJ 1
p-hydroxybenzoic acid efflux pump subunit AaeA 59

Protein length

Min length 368
Max length 408
Mean length (sd) 393.8 (11.5)
Median length 398.0

Protein length distribution