Homologs in group_152

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9 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_07125 FBDBKF_07125 87.8 Morganella morganii S1 pflA pyruvate formate lyase 1-activating protein
EHELCC_03845 EHELCC_03845 87.8 Morganella morganii S2 pflA pyruvate formate lyase 1-activating protein
EHELCC_19995 EHELCC_19995 73.5 Morganella morganii S2 - hypothetical protein
NLDBIP_03845 NLDBIP_03845 87.8 Morganella morganii S4 pflA pyruvate formate lyase 1-activating protein
LHKJJB_09675 LHKJJB_09675 87.8 Morganella morganii S3 pflA pyruvate formate lyase 1-activating protein
HKOGLL_09300 HKOGLL_09300 87.8 Morganella morganii S5 pflA pyruvate formate lyase 1-activating protein
F4V73_RS01310 F4V73_RS01310 88.2 Morganella psychrotolerans pflA pyruvate formate lyase 1-activating protein
PMI_RS12405 PMI_RS12405 30.4 Proteus mirabilis HI4320 - YjjW family glycine radical enzyme activase
PMI_RS13380 PMI_RS13380 33.9 Proteus mirabilis HI4320 cutD choline TMA-lyase-activating enzyme

Distribution of the homologs in the orthogroup group_152

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_152

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P0A9N7 1.67e-164 457 85 0 246 3 pflA Pyruvate formate-lyase 1-activating enzyme Shigella flexneri
P0A9N4 1.67e-164 457 85 0 246 1 pflA Pyruvate formate-lyase 1-activating enzyme Escherichia coli (strain K12)
P0A9N5 1.67e-164 457 85 0 246 3 pflA Pyruvate formate-lyase 1-activating enzyme Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
P0A9N6 1.67e-164 457 85 0 246 3 pflA Pyruvate formate-lyase 1-activating enzyme Escherichia coli O157:H7
P43751 1.22e-129 369 72 0 246 3 pflA Pyruvate formate-lyase 1-activating enzyme Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
O68575 1.1e-71 223 45 3 241 3 act Pyruvate formate-lyase-activating enzyme Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Q8CTX5 1.25e-70 219 49 2 232 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HKI0 1.25e-70 219 49 2 232 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
P0A442 3.78e-70 218 45 1 246 3 pflA Pyruvate formate-lyase-activating enzyme Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Q71ZR3 3.78e-70 218 45 1 246 3 pflA Pyruvate formate-lyase-activating enzyme Listeria monocytogenes serotype 4b (strain F2365)
P0A443 3.78e-70 218 45 1 246 3 pflA Pyruvate formate-lyase-activating enzyme Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Q7A1W8 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain MW2)
Q6GCP9 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain MSSA476)
Q6GK89 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain MRSA252)
Q7A7X5 3.11e-69 216 48 3 236 1 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain N315)
Q99WZ6 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain Mu50 / ATCC 700699)
Q5HJF3 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain COL)
Q2YV52 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain bovine RF122 / ET3-1)
Q2G1D7 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain NCTC 8325 / PS 47)
Q2FK43 3.11e-69 216 48 3 236 3 pflA Pyruvate formate-lyase-activating enzyme Staphylococcus aureus (strain USA300)
Q46267 3.48e-69 215 46 2 227 3 act Pyruvate formate-lyase-activating enzyme Clostridium pasteurianum
A0A069AMK2 7.48e-30 116 27 6 290 3 pflE Trans-4-hydroxy-L-proline dehydratase activating enzyme Clostridioides difficile
A0A124EH39 1.93e-25 104 26 9 310 3 AUL39_03430 Indoleacetate decarboxylase activating enzyme Tractidigestivibacter scatoligenes
E5Y377 8.46e-25 103 28 9 282 1 islB Isethionate sulfite-lyase activating enzyme Bilophila wadsworthia (strain 3_1_6)
Q30W71 1.15e-23 100 27 4 300 1 cutD Choline trimethylamine-lyase activating enzyme Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)
P32675 2.77e-23 98 25 5 274 3 pflC Pyruvate formate-lyase 2-activating enzyme Escherichia coli (strain K12)
C9YHW3 6.12e-22 95 33 8 206 3 hpdA 4-hydroxyphenylacetate decarboxylase activating enzyme Clostridioides difficile (strain R20291)
C9XIS7 6.12e-22 95 33 8 206 3 hpdA 4-hydroxyphenylacetate decarboxylase activating enzyme Clostridioides difficile (strain CD196)
Q18CP3 1.29e-21 94 34 5 170 3 hpdA 4-hydroxyphenylacetate decarboxylase activating enzyme Clostridioides difficile (strain 630)
Q38HX2 1.33e-21 94 30 5 188 1 csdA 4-hydroxyphenylacetate decarboxylase activating enzyme Clostridium scatologenes
Q84F14 1.98e-21 94 34 5 170 1 hpdA 4-hydroxyphenylacetate decarboxylase activating enzyme Clostridioides difficile
A0A318FEA4 2.13e-21 94 34 3 193 3 hpfH (2S)-3-sulfopropanediol dehydratase activating enzyme Klebsiella oxytoca
Q312S3 1.48e-20 91 28 4 194 2 islB Isethionate sulfite-lyase activating enzyme Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)
P39409 4.96e-19 87 29 9 254 1 yjjW Putative glycyl-radical enzyme activating enzyme YjjW Escherichia coli (strain K12)
Q727N0 8.62e-19 86 30 4 189 1 iseH Isethionate sulfite-lyase activating enzyme Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough)
O87941 2.25e-18 85 26 5 212 2 bssD Benzylsuccinate synthase activating enzyme Thauera aromatica
O87941 0.000315 44 55 0 29 2 bssD Benzylsuccinate synthase activating enzyme Thauera aromatica
B8J0R0 4.58e-14 73 33 3 146 1 islB Isethionate sulfite-lyase activating enzyme Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB)
P44743 1.16e-13 72 33 4 128 3 HI_0520 Putative glycyl-radical enzyme activating enzyme HI_0520 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
E5Y7I3 2.84e-13 71 30 4 195 3 hpsH (2S)-3-sulfopropanediol sulfolyase activating enzyme Bilophila wadsworthia (strain 3_1_6)
P75794 5.96e-12 67 30 2 171 3 ybiY Putative pyruvate formate-lyase 3-activating enzyme Escherichia coli (strain K12)
P07075 2.7e-09 57 35 1 70 3 NRDG Anaerobic ribonucleoside-triphosphate reductase-activating protein Enterobacteria phage T4
Q58218 3.36e-08 56 22 7 225 4 MJ0808 Uncharacterized protein MJ0808 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Q9L645 2.55e-06 49 29 7 151 3 nrdG Anaerobic ribonucleoside-triphosphate reductase-activating protein Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
O27295 3.25e-06 50 22 5 183 3 queE 7-carboxy-7-deazaguanine synthase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Q8Z138 3.49e-06 48 29 7 151 3 nrdG Anaerobic ribonucleoside-triphosphate reductase-activating protein Salmonella typhi
Q58624 6.66e-06 49 31 6 122 3 MJ1227 Putative glycyl-radical enzyme activating enzyme MJ1227 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
A2BJ90 2.09e-05 47 27 1 86 3 queE 7-carboxy-7-deazaguanine synthase Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
P0A9N8 2.16e-05 47 27 6 148 1 nrdG Anaerobic ribonucleoside-triphosphate reductase-activating protein Escherichia coli (strain K12)
P0A9N9 2.16e-05 47 27 6 148 3 nrdG Anaerobic ribonucleoside-triphosphate reductase-activating protein Escherichia coli O157:H7
A4WD95 3.1e-05 48 32 5 109 3 rlmN Dual-specificity RNA methyltransferase RlmN Enterobacter sp. (strain 638)
Q59026 5.72e-05 46 24 8 186 3 MJ1632 Putative glycyl-radical enzyme activating enzyme MJ1632 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
A8H242 9.59e-05 46 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
A9KXL1 0.000124 46 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella baltica (strain OS195)
B8E9S4 0.000124 46 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella baltica (strain OS223)
Q1D6I6 0.000137 46 26 6 152 3 rlmN2 Dual-specificity RNA methyltransferase RlmN 2 Myxococcus xanthus (strain DK1622)
A1JKR9 0.000139 46 30 5 109 3 rlmN Dual-specificity RNA methyltransferase RlmN Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
A1S866 0.000149 45 25 10 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Q0HX60 0.000172 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella sp. (strain MR-7)
Q0HKW2 0.000172 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella sp. (strain MR-4)
A3D6W2 0.000205 45 25 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella baltica (strain OS155 / ATCC BAA-1091)
A0KUJ2 0.000207 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella sp. (strain ANA-3)
Q8EC29 0.000208 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)
A6WQQ0 0.00021 45 25 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella baltica (strain OS185)
A1RHQ0 0.000248 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella sp. (strain W3-18-1)
A8GHW8 0.000263 45 30 5 109 3 rlmN Dual-specificity RNA methyltransferase RlmN Serratia proteamaculans (strain 568)
A3QCF9 0.000284 45 25 10 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella loihica (strain ATCC BAA-1088 / PV-4)
B0TLI1 0.000306 45 26 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella halifaxensis (strain HAW-EB4)
A0LBZ1 0.000388 44 24 7 190 3 rlmN Dual-specificity RNA methyltransferase RlmN Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)
P73667 0.000394 43 28 3 102 3 queE 7-carboxy-7-deazaguanine synthase Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Q032R6 0.000397 44 20 5 195 3 rlmN Probable dual-specificity RNA methyltransferase RlmN Lactococcus lactis subsp. cremoris (strain SK11)
Q9CJ27 0.000412 44 20 5 195 3 rlmN Probable dual-specificity RNA methyltransferase RlmN Lactococcus lactis subsp. lactis (strain IL1403)
Q9KM76 0.000472 43 27 1 80 3 nrdG Anaerobic ribonucleoside-triphosphate reductase-activating protein Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
B1KKI9 0.000523 44 25 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella woodyi (strain ATCC 51908 / MS32)
Q8E1A3 0.000524 44 18 5 209 3 rlmN Probable dual-specificity RNA methyltransferase RlmN Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Q8DVG8 0.000579 43 18 5 209 3 rlmN Probable dual-specificity RNA methyltransferase RlmN Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
A8FT67 0.000639 43 25 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella sediminis (strain HAW-EB3)
Q21KT6 0.000716 43 23 9 211 3 rlmN Dual-specificity RNA methyltransferase RlmN Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
A2RHR3 0.000724 43 20 5 196 3 rlmN Probable dual-specificity RNA methyltransferase RlmN Lactococcus lactis subsp. cremoris (strain MG1363)
A1SU36 0.000732 43 21 12 242 3 rlmN Dual-specificity RNA methyltransferase RlmN Psychromonas ingrahamii (strain DSM 17664 / CCUG 51855 / 37)
A8LNF0 0.000746 43 25 8 199 3 rlmN Dual-specificity RNA methyltransferase RlmN Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)
A4Y8U3 0.000832 43 25 11 201 3 rlmN Dual-specificity RNA methyltransferase RlmN Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
B2K9Q3 0.000883 43 29 5 109 3 rlmN Dual-specificity RNA methyltransferase RlmN Yersinia pseudotuberculosis serotype IB (strain PB1/+)

  • Number of RefSeq hits:

General

Source Proteus mirabilis HI4320
Locus tag PMI_RS03465
Feature type CDS
Gene pflA
Product pyruvate formate lyase 1-activating protein
Location 769220 - 769960 (strand: -1)
Length 741 (nucleotides) / 246 (amino acids)

Contig

Accession NC_010554
Length 4063606 nucleotides
Topology circular
Plasmid False

Orthology

Orthogroup group_152
Orthogroup size 10
N. genomes 7

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Genomic region

Domains

PF04055 Radical SAM superfamily
PF13353 4Fe-4S single cluster domain

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1180 Posttranslational modification, protein turnover, chaperones (O) O Pyruvate-formate lyase-activating enzyme

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K04069 pyruvate formate lyase activating enzyme [EC:1.97.1.4] - -

Protein Sequence

MSVLGRIHSFESCGTVDGPGIRFIVFFQGCLMRCLYCHNRDTWDTHGGQIVTVDELMKEAVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKENIHTCLDTNGFVRRYDPVIDELMDVTDLVMLDLKQVNDDIHQKLVGVSNQRTLEFARYLAKRGQKTWIRYVVVPGWSDDDDSAHRLGEFIKDMKNIEKVELLPYHELGKHKWVALGEEYKLDGIHPPSKETMENVKAIIASYGHKVMY

Flanking regions ( +/- flanking 50bp)

GCCCCTACTTTGGGGCCTTTTTATCTAGACAGTTTTGGAGTAACCCTGTTATGTCCGTACTTGGTCGTATCCACTCATTTGAATCCTGCGGTACTGTTGACGGTCCCGGAATACGCTTTATTGTTTTCTTCCAAGGATGCCTAATGAGATGCCTCTATTGTCACAACCGTGACACATGGGATACTCATGGTGGGCAAATCGTCACAGTTGATGAATTAATGAAAGAGGCAGTGACTTATCGTCACTTTATGAATGCCTCTGGTGGTGGCGTTACAGCTTCTGGTGGTGAAGCTATCTTACAAGCAGAATTTGTACGTGATTGGTTCCGTGCTTGTAAAAAAGAAAATATCCATACCTGCTTAGATACTAACGGTTTTGTACGCCGTTATGATCCTGTCATCGATGAATTAATGGACGTGACTGATTTAGTCATGCTGGATTTAAAACAAGTGAATGATGACATTCACCAAAAACTGGTTGGTGTTTCTAACCAACGTACACTGGAATTCGCCCGCTATTTAGCTAAACGAGGCCAAAAAACCTGGATACGTTACGTAGTTGTGCCCGGTTGGTCTGATGATGATGATTCTGCTCATCGTTTAGGCGAATTTATAAAAGATATGAAAAATATCGAAAAAGTCGAGCTTCTCCCTTACCACGAATTAGGTAAACATAAATGGGTTGCTTTAGGAGAAGAGTATAAACTCGATGGTATTCATCCACCGTCAAAAGAGACGATGGAAAATGTTAAAGCAATTATTGCATCTTATGGTCATAAAGTGATGTATTAAGCTTTTATACACCCCCATTTTAAAAAGCAGTGCACAATGTACTGCTTTTT