Homologs in group_43

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13 homologs were identified in 7 genomes with OrthoFinder.
The following table displays the locus tag of each homolog, the organism to which it belongs, the gene name and product.

Locus tag Identity Source Gene Product
FBDBKF_04605 FBDBKF_04605 55.5 Morganella morganii S1 emrA Multidrug resistance efflux pump EmrA
EHELCC_04985 EHELCC_04985 100.0 Morganella morganii S2 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
EHELCC_05895 EHELCC_05895 55.5 Morganella morganii S2 emrA Multidrug resistance efflux pump EmrA
NLDBIP_04985 NLDBIP_04985 100.0 Morganella morganii S4 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
NLDBIP_06215 NLDBIP_06215 55.5 Morganella morganii S4 emrA Multidrug resistance efflux pump EmrA
LHKJJB_03095 LHKJJB_03095 55.5 Morganella morganii S3 emrA Multidrug resistance efflux pump EmrA
LHKJJB_13645 LHKJJB_13645 100.0 Morganella morganii S3 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
HKOGLL_06570 HKOGLL_06570 55.5 Morganella morganii S5 emrA Multidrug resistance efflux pump EmrA
HKOGLL_12890 HKOGLL_12890 100.0 Morganella morganii S5 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
F4V73_RS00155 F4V73_RS00155 88.8 Morganella psychrotolerans emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
F4V73_RS09055 F4V73_RS09055 55.5 Morganella psychrotolerans - EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit
PMI_RS01985 PMI_RS01985 72.6 Proteus mirabilis HI4320 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
PMI_RS15260 PMI_RS15260 27.2 Proteus mirabilis HI4320 - HlyD family secretion protein

Distribution of the homologs in the orthogroup group_43

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Number of homologs in each genome (first column) and amino-acid identity of the closest homolog (second column).

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Phylogeny of the RefSeq best hits of group_43

Swissprot accession Eval Score ID (%) N gaps Alignment length Annot score Gene Description Organism
P27303 1e-172 490 63 1 391 1 emrA Multidrug export protein EmrA Escherichia coli (strain K12)
P52599 3.83e-128 377 50 3 380 2 emrK Probable multidrug resistance protein EmrK Escherichia coli (strain K12)
P44928 9.6e-114 340 47 0 353 3 emrA Multidrug export protein EmrA Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Q9RQ30 1.59e-93 288 45 3 349 1 farA Fatty acid resistance protein FarA Neisseria gonorrhoeae
P0DPR6 9.86e-42 153 33 9 332 2 emrA Colistin resistance protein EmrA Acinetobacter baumannii (strain ATCC 17978 / DSM 105126 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
Q8FAX1 1.27e-23 103 27 7 314 3 mdtN Multidrug resistance protein MdtN Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q83P86 1.56e-23 103 27 7 314 3 mdtN Multidrug resistance protein MdtN Shigella flexneri
Q8X5R2 3.15e-23 102 27 7 314 3 mdtN Multidrug resistance protein MdtN Escherichia coli O157:H7
P32716 4.14e-23 102 27 7 314 2 mdtN Multidrug resistance protein MdtN Escherichia coli (strain K12)
P76185 8.94e-22 97 27 9 311 3 ydhJ Uncharacterized protein YdhJ Escherichia coli (strain K12)
A8A550 1.12e-15 80 27 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O9:H4 (strain HS)
B7M0V3 1.46e-15 80 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O8 (strain IAI1)
A8AQD5 3.14e-15 79 27 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Q0T047 3.42e-15 79 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Shigella flexneri serotype 5b (strain 8401)
P46482 3.42e-15 79 26 9 316 2 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain K12)
B1XHL3 3.42e-15 79 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain K12 / DH10B)
C4ZSX9 3.42e-15 79 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain K12 / MC4100 / BW2952)
B7LHU9 3.42e-15 79 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain 55989 / EAEC)
A7ZSD5 3.42e-15 79 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O139:H28 (strain E24377A / ETEC)
Q83Q03 4.54e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Shigella flexneri
Q32B98 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Shigella dysenteriae serotype 1 (strain Sd197)
Q1R698 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain UTI89 / UPEC)
B1LGK7 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain SMS-3-5 / SECEC)
B6I1V9 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain SE11)
B1IQN8 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)
Q8FD50 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Q0TCM4 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O6:K15:H31 (strain 536 / UPEC)
A1AGD4 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O1:K1 / APEC
B7N0M6 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O81 (strain ED1a)
B7MC02 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O45:K1 (strain S88 / ExPEC)
B7UJX3 4.99e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O127:H6 (strain E2348/69 / EPEC)
B7NDL9 5.43e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
B7NLF9 7.21e-15 78 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Q3YX06 9.3e-15 77 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Shigella sonnei (strain Ss046)
A7MJB1 3.22e-14 76 25 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Cronobacter sakazakii (strain ATCC BAA-894)
B5YSW7 3.71e-14 75 27 10 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O157:H7 (strain EC4115 / EHEC)
Q8X9E5 3.71e-14 75 27 10 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia coli O157:H7
Q7CPM8 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8XF83 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella typhi
B5BGR9 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi A (strain AKU_12601)
C0PZR0 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi C (strain RKS4594)
A9N863 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Q5PJT8 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella paratyphi A (strain ATCC 9150 / SARB42)
B4T775 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella newport (strain SL254)
B4TJT9 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella heidelberg (strain SL476)
B5R1A8 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella enteritidis PT4 (strain P125109)
B5FIU3 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella dublin (strain CT_02021853)
Q57JA3 5.72e-14 75 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella choleraesuis (strain SC-B67)
B4TX73 6.16e-14 75 27 10 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella schwarzengrund (strain CVM19633)
B5F7M5 6.16e-14 75 27 10 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella agona (strain SL483)
B7LRL6 1.63e-13 74 25 8 318 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
A9MNW9 2.49e-13 73 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
B5REW3 5.55e-13 72 26 9 316 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Salmonella gallinarum (strain 287/91 / NCTC 13346)
O31593 8.02e-13 70 30 3 139 3 yhbJ Putative efflux system component YhbJ Bacillus subtilis (strain 168)
A8GK45 1.18e-12 71 24 9 331 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Serratia proteamaculans (strain 568)
B5XSP8 1.59e-12 71 25 10 320 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Klebsiella pneumoniae (strain 342)
A1JRH9 3.16e-12 70 27 13 318 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
A4WF55 7.92e-12 69 24 9 314 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Enterobacter sp. (strain 638)
Q6DAH5 1.55e-11 68 25 11 319 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
A7FDT5 4.25e-11 67 25 9 308 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
C6DIM2 5.16e-11 66 25 11 325 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Pectobacterium carotovorum subsp. carotovorum (strain PC1)
B2VGW1 6.15e-11 66 27 10 280 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)
B1JKI2 2.51e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Q665H1 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pseudotuberculosis serotype I (strain IP32953)
A4THE9 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pestis (strain Pestoides F)
Q1CDW6 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pestis bv. Antiqua (strain Nepal516)
A9R1V9 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pestis bv. Antiqua (strain Angola)
Q8ZAU9 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pestis
B2K437 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Q1C1L2 3.01e-10 64 25 9 307 3 aaeA p-hydroxybenzoic acid efflux pump subunit AaeA Yersinia pestis bv. Antiqua (strain Antiqua)
Q9L9D4 1.08e-08 60 26 10 283 3 None UPF0194 membrane protein in asrC 5'region (Fragment) Acidithiobacillus ferridurans
A8AIZ1 2.7e-06 52 23 5 258 3 CKO_02332 UPF0194 membrane protein CKO_02332 Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
A1JSL8 3.28e-06 52 23 3 266 3 YE2891 UPF0194 membrane protein YE2891 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
B2K8W1 1.42e-05 50 24 2 222 3 YPTS_1292 UPF0194 membrane protein YPTS_1292 Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Q66D37 1.42e-05 50 24 2 222 3 YPTB1212 UPF0194 membrane protein YPTB1212 Yersinia pseudotuberculosis serotype I (strain IP32953)
Q93AA7 2.01e-05 49 24 2 222 3 YP_0975 UPF0194 membrane protein YP_0975 Yersinia pestis
B1JSP3 2.01e-05 49 24 2 222 3 YPK_2900 UPF0194 membrane protein YPK_2900 Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Q1CFT7 2.01e-05 49 24 2 222 3 YPN_2816 UPF0194 membrane protein YPN_2816 Yersinia pestis bv. Antiqua (strain Nepal516)
A7FKJ7 2.01e-05 49 24 2 222 3 YpsIP31758_2812 UPF0194 membrane protein YpsIP31758_2812 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Q1C912 2.01e-05 49 24 2 222 3 YPA_1093 UPF0194 membrane protein YPA_1093 Yersinia pestis bv. Antiqua (strain Antiqua)
P0AFV0 4.3e-05 48 23 8 274 1 yibH Inner membrane protein YibH Escherichia coli (strain K12)
P0AFV1 4.3e-05 48 23 8 274 3 yibH Inner membrane protein YibH Escherichia coli O157:H7
P24130 0.000107 45 31 1 73 4 fusE Fusaric acid resistance protein FusE Burkholderia cepacia
A4W8D7 0.000222 46 24 2 222 3 Ent638_1286 UPF0194 membrane protein Ent638_1286 Enterobacter sp. (strain 638)

  • Number of RefSeq hits:

General

Source Morganella morganii S1
Locus tag FBDBKF_10185
Feature type CDS
Gene emrA
Product multidrug efflux MFS transporter periplasmic adaptor subunit EmrA
Location 129194 - 130372 (strand: 1)
Length 1179 (nucleotides) / 392 (amino acids)

Contig

Accession contig_11
Length 143616 nucleotides
Topology linear
Plasmid False

Orthology

Orthogroup group_43
Orthogroup size 14
N. genomes 7

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Genomic region

Domains

PF00529 Cation efflux system protein CusB domain 1
PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion

COG entry Annotation(s)

ID Function(s) descr. Function(s) cat. Description
COG1566 Defense mechanisms (V) V Multidrug resistance efflux pump EmrA

Kegg Ortholog Annotation(s)

KO Description Pathways Modules
K03543 membrane fusion protein, multidrug efflux system - -

Protein Sequence

MSVSEETQAVQPPVRNKKRQRRNALMLLTLLFVLLGAAYTVYWFMVLRHHESTDNAYVTGNQVIVMSQVPGSVTTVSVDNTDYVTAGTLLVQLDKRDAGLALEKAQVALANSVRQTHQQMINSRQLLAGIEVRRSELTRLQNDLRRREVLGAQNVIGKEELQHAREAVVSAKAQLDVATEQFNANKAVILDTPLSEQPAVKQAATEVRNAWLALERTDIRSPVDGYVSRRSVQVGAQITPATPLMAVVPATGMWIDANFKETQLSAMRIGQPAKVITDFYGDKVVFTGTVTGLDMGTGSAFSLLPAQNASGNWIKVVQRLPVRIALDPAQLEKYPLRIGLSGDVTVDTQNTDGPVLSKSVRTDPAYHTSALSIDMQPADQMIAEIISRNAGQ

Flanking regions ( +/- flanking 50bp)

GTTATGTCATGCAACACCTTAAAAAAAAGAACAATATCCGGAGATAACTGATGAGTGTCAGTGAGGAAACTCAGGCTGTCCAGCCCCCAGTCCGTAACAAAAAACGACAACGCCGTAATGCGCTGATGTTACTGACATTACTGTTTGTATTACTGGGTGCGGCTTACACCGTTTACTGGTTTATGGTGCTCCGCCACCATGAATCGACCGATAACGCCTATGTCACCGGCAACCAGGTGATTGTGATGTCACAGGTTCCCGGCAGTGTCACCACTGTCAGTGTGGATAATACCGATTATGTGACCGCCGGAACACTGCTGGTGCAGCTCGATAAACGGGATGCCGGACTGGCGCTGGAAAAAGCACAGGTTGCGCTGGCAAACAGTGTCCGCCAGACACATCAGCAGATGATCAACAGCCGTCAGTTGCTGGCCGGTATTGAAGTCCGCCGTTCAGAACTGACCCGCCTGCAGAATGACCTGCGCCGTCGTGAAGTACTGGGCGCACAGAATGTGATCGGCAAAGAAGAACTTCAGCACGCCCGTGAAGCCGTGGTGAGCGCCAAAGCGCAGCTGGATGTTGCCACCGAGCAGTTTAATGCCAACAAAGCCGTGATCCTCGATACCCCGCTGAGCGAACAGCCGGCAGTGAAACAGGCGGCCACTGAAGTGCGTAACGCCTGGCTGGCACTGGAGCGGACCGATATCCGCAGCCCGGTGGACGGTTATGTCTCCCGGCGCAGTGTGCAGGTCGGTGCACAAATCACCCCTGCCACCCCGCTGATGGCCGTGGTTCCGGCCACCGGTATGTGGATTGACGCCAACTTTAAAGAAACCCAGCTCAGCGCCATGCGTATCGGGCAGCCGGCCAAAGTGATCACTGATTTCTACGGTGACAAAGTGGTCTTCACCGGTACCGTTACCGGGCTGGACATGGGCACCGGTAGCGCCTTCTCCCTGCTGCCTGCGCAGAATGCCAGTGGTAACTGGATCAAAGTAGTACAGCGTCTGCCGGTGCGTATCGCGCTGGATCCGGCACAGCTGGAGAAATACCCGCTGCGTATCGGTCTTTCCGGTGATGTCACCGTGGACACGCAGAATACTGACGGCCCGGTGCTGTCGAAAAGCGTGCGCACCGATCCGGCCTATCATACCAGTGCCCTGAGCATTGATATGCAACCGGCGGATCAGATGATCGCTGAGATTATCAGCCGCAATGCCGGTCAGTAAGGGGTCAGGGTTATGCAGGCGCCACTGACCGGAGCAAGACTGGCCTGGAT