M00924


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Kegg module M00924 is descriptive of Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide module, which is part of the Metabolism of cofactors and vitamins category and Cofactor and vitamin metabolism subcategory.

In General the list of Ko entries of M00924 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00924 Kegg module

Id Description
K00595 precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:2.1.1.132 2.1.1.289 2.1.1.196]
K02188 cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
K02189 cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
K02190 sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K02191 cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
K02224 cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
K02302 uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
K02304 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03394 precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
K03399 cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
K03795 sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K05895 precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106]
K05934 precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
K05936 precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
K06042 precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
K13541 cobalt-precorrin 5A hydrolase / cobalt-factor III methyltransferase / precorrin-3B C17-methyltransferase [EC:3.7.1.12 2.1.1.272 2.1.1.131]
K13542 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K21479 cobalt-factor III methyltransferase [EC:2.1.1.272]
K22011 sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
K24866 precorrin-2 dehydrogenase [EC:1.3.1.76]