K01012


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K01012, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K01012
KO K01012
Description biotin synthase [EC:2.8.1.6]

KO part of 3 pathways

Biotin metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 4 modules

M00123 Cofactor and vitamin metabolism Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00573 Cofactor and vitamin metabolism Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00577 Cofactor and vitamin metabolism Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00950 Cofactor and vitamin metabolism Biotin biosynthesis, BioU pathway, pimeloyl-ACP/CoA => biotin

Occurence in the database

K01012 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1490 PMI_RS02970 655074 656111 1 bioB biotin synthase BioB Proteus mirabilis HI4320
1 group_1490 FBDBKF_09620 22535 23572 -1 bioB biotin synthase BioB Morganella morganii S1
2 group_1490 EHELCC_04420 214500 215537 -1 bioB biotin synthase BioB Morganella morganii S2
3 group_1490 NLDBIP_04420 214296 215333 -1 bioB biotin synthase BioB Morganella morganii S4
4 group_1490 LHKJJB_14210 120045 121082 1 bioB biotin synthase BioB Morganella morganii S3
5 group_1490 HKOGLL_12325 23316 24353 -1 bioB biotin synthase BioB Morganella morganii S5
6 group_1490 F4V73_RS00720 150021 151058 1 bioB biotin synthase BioB Morganella psychrotolerans