K00941


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00941
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00941
KO K00941
Description hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]

KO part of 3 pathways

Thiamine metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 4 modules

M00127 Cofactor and vitamin metabolism Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00895 Cofactor and vitamin metabolism Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP
M00896 Cofactor and vitamin metabolism Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
M00899 Cofactor and vitamin metabolism Thiamine salvage pathway, HMP/HET => TMP

Occurence in the database

K00941 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_2218 FBDBKF_16435 10816 11613 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S1
1 group_2218 EHELCC_08300 127802 128599 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S2
2 group_2218 NLDBIP_08625 127802 128599 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S4
3 group_2218 LHKJJB_05640 128560 129357 -1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S3
4 group_2218 HKOGLL_05275 112393 113190 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S5
5 group_2218 F4V73_RS02955 626326 627123 1 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Morganella psychrotolerans
6 group_2218 PMI_RS07770 1701689 1702486 -1 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Proteus mirabilis HI4320