K00941


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00941, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00941
KO K00941
Description hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]

KO part of 3 pathways

Thiamine metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 4 modules

M00127 Cofactor and vitamin metabolism Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00895 Cofactor and vitamin metabolism Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP
M00896 Cofactor and vitamin metabolism Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
M00899 Cofactor and vitamin metabolism Thiamine salvage pathway, HMP/HET => TMP

Occurence in the database

K00941 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_2182 PMI_RS07770 1701689 1702486 -1 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Proteus mirabilis HI4320
1 group_2182 FBDBKF_16435 10816 11613 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S1
2 group_2182 EHELCC_08300 127802 128599 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S2
3 group_2182 NLDBIP_08625 127802 128599 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S4
4 group_2182 LHKJJB_05640 128560 129357 -1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S3
5 group_2182 HKOGLL_05275 112393 113190 1 thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Morganella morganii S5
6 group_2182 F4V73_RS02955 626326 627123 1 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Morganella psychrotolerans