M00307


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Kegg module M00307 is descriptive of Pyruvate oxidation, pyruvate => acetyl-CoA module, which is part of the Carbohydrate metabolism category and Central carbohydrate metabolism subcategory.

In General the list of Ko entries of M00307 Kegg module is reported. Each Ko entry is clickable and redirects the user to the specifc Kegg Ortholog page with further info about its identification within the genomes in association with the Orthogroups classification.
In Profile + homologs the distribution of the Kegg entries of Pyruvate oxidation, pyruvate => acetyl-CoA module is displayed. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
If all the Kegg entries required by the model to be funcitonal are present, the letter 'C'' is reported, otherwise 'I' singals an incomplet module.
Note that a Kegg module may accept alternative Ko or set of Kegg orthologs to be functional. This means that some missing Ko do not impact the module completeness.

Check the composition of M00307 Kegg module

Id Description
K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K00163 pyruvate dehydrogenase E1 component [EC:1.2.4.1]
K00169 pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
K00170 pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
K00171 pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
K00172 pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
K00189 2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
K00382 dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00627 pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
K03737 pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
K13997 dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex