K00012


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00012
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00012
KO K00012
Description UDPglucose 6-dehydrogenase [EC:1.1.1.22]

KO part of 7 pathways

Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Amino sugar and nucleotide sugar metabolism
Biosynthesis of various nucleotide sugars
Metabolic pathways
Biosynthesis of cofactors
Biosynthesis of nucleotide sugars

KO part of 4 modules

M00014 Other carbohydrate metabolism Glucuronate pathway (uronate pathway)
M00129 Other carbohydrate metabolism Ascorbate biosynthesis, animals, glucose-1P => ascorbate
M00997 Nucleotide sugar biosynthesis UDP-Xyl/L-Ara biosynthesis, UDP-Glc => UDP-Xyl => UDP-L-Ala
M00999 Nucleotide sugar biosynthesis UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA

Occurence in the database

K00012 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_462 FBDBKF_05355 79790 81133 -1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S1
1 group_462 EHELCC_12235 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S2
2 group_462 NLDBIP_12575 100316 101659 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S4
3 group_462 LHKJJB_12435 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S3
4 group_462 HKOGLL_11050 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S5
5 group_462 F4V73_RS05810 1236699 1238042 -1 UDP-glucose/GDP-mannose dehydrogenase family protein Morganella psychrotolerans
6 group_462 PMI_RS15770 3502000 3503166 -1 nucleotide sugar dehydrogenase Proteus mirabilis HI4320