K00012


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected Kegg Orthologs K00012, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the Kegg Orthologs within the database. 7 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the Kegg Ortholog(s) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Orthologs has been clustered.
In red the Kegg Orthologs with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and Kegg Orthologs prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Orthologs.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Orthologs prediction.

Description

External link K00012
KO K00012
Description UDPglucose 6-dehydrogenase [EC:1.1.1.22]

KO part of 7 pathways

Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Amino sugar and nucleotide sugar metabolism
O-Antigen nucleotide sugar biosynthesis
Metabolic pathways
Biosynthesis of cofactors
Biosynthesis of nucleotide sugars

KO part of 2 modules

M00014 Other carbohydrate metabolism Glucuronate pathway (uronate pathway)
M00129 Other carbohydrate metabolism Ascorbate biosynthesis, animals, glucose-1P => ascorbate

Occurence in the database

K00012 is associated with 7 different proteins (see tab "Protein list" and "Profile")
The 7 proteins are classified into 1 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_970 PMI_RS15770 3502000 3503166 -1 nucleotide sugar dehydrogenase Proteus mirabilis HI4320
1 group_970 FBDBKF_05355 79790 81133 -1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S1
2 group_970 EHELCC_12235 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S2
3 group_970 NLDBIP_12575 100316 101659 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S4
4 group_970 LHKJJB_12435 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S3
5 group_970 HKOGLL_11050 100361 101704 1 ugd UDP-glucose 6-dehydrogenase Morganella morganii S5
6 group_970 F4V73_RS05810 1236699 1238042 -1 UDP-glucose/GDP-mannose dehydrogenase family protein Morganella psychrotolerans