COG0262


Help to interpret the results

Three outputs have been generated:
General: this result contains the description and frequency of the selected COG entries COG0262, of which KO pathways and KO modules it is part. Additionally, its occurence in the database is reported.
Proteins list: list of occurences of the COG entries within the database. 18 occurences are identified. The table reports the orthogroup, the organism in which each occurrence has been found, and the locus tag enriched by start and stop position, strand, gene name and product.
Clicking on the Ortohgroup name or locus you will be redirected to further info.
Profiles: Phylogenetic tree annotated with
- the presence of the COG entry(ies) of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported COG entries has been clustered.
In red the COG entries with positive hit(s) in the corresponding genome.
In green the discrepencies between orthogroup clustering and COG entries prediction. Green homologs (same orthogroup) are not positive hit(s) for the considered COG entries.

Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or COG entries prediction.

Description

Description Dihydrofolate reductase
Function(s) descr. Coenzyme transport and metabolism (H)

Occurence in the database

COG0262 is associated with 18 different proteins (see tab "Protein list" and "Profile")
The 18 proteins are classified into 4 different orthogroup(s)
# Orthogroup Locus Start Stop S. Gene Product Organism
0 group_283 FBDBKF_06280 88639 89133 -1 folA type 3 dihydrofolate reductase Morganella morganii S1
1 group_3671 FBDBKF_20545 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S1
2 group_3641 FBDBKF_20645 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S1
3 group_283 EHELCC_09325 89211 89705 -1 folA type 3 dihydrofolate reductase Morganella morganii S2
4 group_3641 EHELCC_19890 671 1144 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S2
5 group_283 NLDBIP_09705 89211 89705 -1 folA type 3 dihydrofolate reductase Morganella morganii S4
6 group_3671 NLDBIP_19860 155 652 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S4
7 group_3641 NLDBIP_19925 145 618 1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S4
8 group_283 LHKJJB_08050 127533 128027 1 folA type 3 dihydrofolate reductase Morganella morganii S3
9 group_3671 LHKJJB_19825 387 884 1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S3
10 group_3641 LHKJJB_19885 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S3
11 group_283 HKOGLL_07600 127533 128027 1 folA type 3 dihydrofolate reductase Morganella morganii S5
12 group_3671 HKOGLL_19695 1833 2330 -1 dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 Morganella morganii S5
13 group_3641 HKOGLL_19725 216 689 -1 dfrA15 trimethoprim-resistant dihydrofolate reductase DfrA15 Morganella morganii S5
14 group_4032 F4V73_RS05310 1128284 1128838 -1 dihydrofolate reductase family protein Morganella psychrotolerans
15 group_283 F4V73_RS15640 124958 125452 1 folA type 3 dihydrofolate reductase Morganella psychrotolerans
16 group_283 F4V73_RS17885 19299 19784 -1 dihydrofolate reductase Morganella psychrotolerans
17 group_283 PMI_RS11560 2549655 2550140 -1 folA type 3 dihydrofolate reductase Proteus mirabilis HI4320