Help to interpret the results
The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Proteus mirabilis HI4320 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Pyrimidine metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.
Check the composition of the Pyrimidine metabolism pathway
| KO | Description | #in this genome | All occurrences |
|---|---|---|---|
| K00207 | dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] | 0 | 0 |
| K00226 | dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] | 0 | 0 |
| K00254 | dihydroorotate dehydrogenase [EC:1.3.5.2] | 1 | 7 |
| K00524 | ribonucleotide reductase, class II [EC:1.17.4.2] | 0 | 0 |
| K00525 | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] | 2 | 15 |
| K00526 | ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] | 2 | 15 |
| K00527 | ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] | 0 | 0 |
| K00560 | thymidylate synthase [EC:2.1.1.45] | 1 | 13 |
| K00608 | aspartate carbamoyltransferase [EC:2.1.3.2] | 0 | 0 |
| K00609 | aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] | 1 | 7 |
| K00610 | aspartate carbamoyltransferase regulatory subunit | 1 | 7 |
| K00756 | pyrimidine-nucleoside phosphorylase [EC:2.4.2.2] | 0 | 0 |
| K00757 | uridine phosphorylase [EC:2.4.2.3] | 1 | 7 |
| K00758 | thymidine phosphorylase [EC:2.4.2.4] | 1 | 7 |
| K00761 | uracil phosphoribosyltransferase [EC:2.4.2.9] | 1 | 7 |
| K00762 | orotate phosphoribosyltransferase [EC:2.4.2.10] | 1 | 7 |
| K00857 | thymidine kinase [EC:2.7.1.21] | 1 | 7 |
| K00876 | uridine kinase [EC:2.7.1.48] | 1 | 7 |
| K00893 | deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113] | 0 | 0 |
| K00940 | nucleoside-diphosphate kinase [EC:2.7.4.6] | 1 | 7 |
| K00943 | dTMP kinase [EC:2.7.4.9] | 1 | 7 |
| K00945 | CMP/dCMP kinase [EC:2.7.4.25] | 1 | 7 |
| K01081 | 5'-nucleotidase [EC:3.1.3.5] | 1 | 1 |
| K01119 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] | 1 | 7 |
| K01240 | uridine nucleosidase [EC:3.2.2.3] | 0 | 0 |
| K01250 | pyrimidine-specific ribonucleoside hydrolase [EC:3.2.2.-] | 0 | 0 |
| K01431 | beta-ureidopropionase [EC:3.5.1.6] | 0 | 0 |
| K01464 | dihydropyrimidinase [EC:3.5.2.2] | 0 | 6 |
| K01465 | dihydroorotase [EC:3.5.2.3] | 0 | 0 |
| K01485 | cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] | 1 | 7 |
| K01489 | cytidine deaminase [EC:3.5.4.5] | 1 | 7 |
| K01493 | dCMP deaminase [EC:3.5.4.12] | 0 | 1 |
| K01494 | dCTP deaminase [EC:3.5.4.13] | 1 | 7 |
| K01510 | apyrase [EC:3.6.1.5] | 0 | 0 |
| K01511 | ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] | 0 | 0 |
| K01513 | ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] | 0 | 0 |
| K01518 | bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] | 0 | 0 |
| K01520 | dUTP diphosphatase [EC:3.6.1.23] | 1 | 7 |
| K01591 | orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] | 1 | 7 |
| K01937 | CTP synthase [EC:6.3.4.2] | 1 | 7 |
| K01954 | carbamoyl-phosphate synthase [EC:6.3.5.5] | 0 | 0 |
| K01955 | carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] | 1 | 7 |
| K01956 | carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] | 1 | 7 |
| K02566 | 5'-nucleotidase [EC:3.1.3.5] | 0 | 0 |
| K02823 | dihydroorotate dehydrogenase electron transfer subunit | 0 | 0 |
| K02825 | pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] | 0 | 0 |
| K03365 | cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] | 0 | 0 |
| K03465 | thymidylate synthase (FAD) [EC:2.1.1.148] | 0 | 0 |
| K03787 | 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] | 1 | 7 |
| K04765 | nucleoside triphosphate diphosphatase [EC:3.6.1.9] | 1 | 7 |
| K05961 | deoxynucleoside kinase [EC:2.7.1.145] | 0 | 0 |
| K06016 | beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] | 0 | 5 |
| K06287 | nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] | 1 | 7 |
| K06952 | 5'-nucleotidase [EC:3.1.3.89] | 0 | 4 |
| K06966 | pyrimidine/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-] | 1 | 7 |
| K07023 | 5'-deoxynucleotidase [EC:3.1.3.89] | 0 | 0 |
| K07043 | UTP pyrophosphatase [EC:3.6.1.-] | 0 | 0 |
| K08320 | (d)CTP diphosphatase [EC:3.6.1.65] | 0 | 0 |
| K08693 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] | 0 | 0 |
| K08722 | 5'-deoxynucleotidase [EC:3.1.3.89] | 1 | 7 |
| K08723 | pyrimidine 5'-nucleotidase [EC:3.1.3.-] | 0 | 0 |
| K09018 | pyrimidine oxygenase [EC:1.14.99.46] | 0 | 0 |
| K09019 | 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-] | 0 | 0 |
| K09020 | ureidoacrylate peracid hydrolase [EC:3.5.1.110] | 0 | 0 |
| K09021 | aminoacrylate peracid reductase | 0 | 0 |
| K09023 | aminoacrylate hydrolase [EC:3.5.1.-] | 0 | 0 |
| K09024 | flavin reductase [EC:1.5.1.-] | 0 | 0 |
| K09769 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] | 0 | 0 |
| K09887 | dCTP deaminase (dUMP-forming) [EC:3.5.4.30] | 0 | 0 |
| K09903 | uridylate kinase [EC:2.7.4.22] | 1 | 7 |
| K09913 | purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] | 0 | 0 |
| K10213 | ribosylpyrimidine nucleosidase [EC:3.2.2.8] | 0 | 0 |
| K10807 | ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] | 0 | 0 |
| K10808 | ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] | 0 | 0 |
| K11540 | carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] | 0 | 0 |
| K11541 | carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2] | 0 | 0 |
| K11751 | 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] | 1 | 7 |
| K12304 | soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] | 0 | 0 |
| K12305 | ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6] | 0 | 0 |
| K12700 | non-specific riboncleoside hydrolase [EC:3.2.2.-] | 0 | 0 |
| K13421 | uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] | 0 | 0 |
| K13799 | pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25] | 0 | 0 |
| K13800 | UMP-CMP kinase [EC:2.7.4.14] | 0 | 0 |
| K13809 | UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14] | 0 | 0 |
| K13998 | dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] | 0 | 0 |
| K14641 | apyrase [EC:3.6.1.5] | 0 | 0 |
| K14642 | golgi apyrase [EC:3.6.1.5] | 0 | 0 |
| K15519 | deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] | 0 | 0 |
| K16066 | 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] | 1 | 7 |
| K16328 | pseudouridine kinase [EC:2.7.1.83] | 0 | 5 |
| K16329 | pseudouridylate synthase [EC:4.2.1.70] | 0 | 5 |
| K16330 | pseudouridylate synthase / pseudouridine kinase [EC:4.2.1.70 2.7.1.83] | 0 | 0 |
| K16904 | dCTP diphosphatase [EC:3.6.1.12] | 0 | 0 |
| K17722 | dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1] | 0 | 0 |
| K17723 | dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1] | 0 | 0 |
| K17828 | dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] | 0 | 0 |
| K18533 | adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6] | 0 | 0 |
| K18931 | AMP phosphorylase [EC:2.4.2.57] | 0 | 0 |
| K19794 | barbiturase [EC:3.5.2.1] | 0 | 0 |
| K19795 | ureidomalonase [EC:3.5.1.95] | 0 | 0 |
| K19796 | Straboviridae dCMP hydroxymethylase [EC:2.1.2.8] | 0 | 0 |
| K19797 | Straboviridae T-even-induced deoxynucleotide kinase [EC:2.7.4.12] | 0 | 0 |
| K19970 | 5'-nucleotidase [EC:3.1.3.5] | 0 | 0 |
| K21057 | cytidine kinase [EC:2.7.1.213] | 0 | 0 |
| K21636 | ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | 1 | 7 |
| K22026 | nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] | 0 | 0 |
| K24242 | 7-methylguanosine nucleotidase [EC:3.1.3.91] | 0 | 0 |
| K24670 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / phosphoenolpyruvate phosphatase [EC:3.1.4.16 3.1.3.60] | 0 | 0 |
| K25434 | pyrimidine 5'-nucleotidase [EC:3.1.3.-] | 0 | 0 |
| K25435 | putative bifunctional nucleoside triphosphate pyrophosphatase / methyltransferase [EC:3.6.1.- 2.1.1.-] | 0 | 0 |
| K25589 | inosine/uridine nucleosidase [EC:3.2.2.2 3.2.2.3] | 0 | 5 |
| K26955 | bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] | 0 | 0 |