K00254


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00254
Protein list: lists the 7 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00254
KO K00254
Description dihydroorotate dehydrogenase [EC:1.3.5.2]

KO part of 3 pathways

Pyrimidine metabolism
Metabolic pathways
Biosynthesis of cofactors

KO part of 1 modules

M00051 Pyrimidine metabolism De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP

Occurence in the database

K00254 is associated with 7 different proteins
The 7 proteins are classified into 1 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_1308 FBDBKF_07280 137673 138683 1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella morganii S1
1 group_1308 EHELCC_03690 47503 48513 -1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella morganii S2
2 group_1308 NLDBIP_03690 47299 48309 -1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella morganii S4
3 group_1308 LHKJJB_09520 47413 48423 -1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella morganii S3
4 group_1308 HKOGLL_09455 142629 143639 1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella morganii S5
5 group_1308 F4V73_RS01465 325974 326984 1 pyrD quinone-dependent dihydroorotate dehydrogenase Morganella psychrotolerans
6 group_1308 PMI_RS03790 857583 858593 1 pyrD quinone-dependent dihydroorotate dehydrogenase Proteus mirabilis HI4320