K00525


Help to interpret the results

Three outputs have been generated:
General: this tab contains the description, occurence in the database and other information related to the selected Kegg Ortholog K00525
Protein list: lists the 14 occurences of the Kegg Ortholog within the database. The table reports information on each occurence.
Profile: phylogenetic tree annotated with
- the presence of the Kegg Ortholog of interest within all the genomes of the database (first column)
- the size of the orthogroup(s) in which the reported Kegg Ortholog has been clustered.
Orthogroups are shown in red if they are annotated with that particular Kegg Ortholog in a given genome , in green otherwise, i.e. if there is a discrepency between orthogroup clustering and Kegg Ortholog prediction.
Green homologs (same orthogroup) are not positive hit(s) for the considered Kegg Ortholog.
Variations within orthogroups may be due to the clustering of multi domain proteins or because of erroneous homolog clustering or Kegg Ortholog prediction.

Description

External link K00525
KO K00525
Description ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]

KO part of 4 pathways

Purine metabolism
Pyrimidine metabolism
Metabolic pathways
Nucleotide metabolism

KO part of 2 modules

M00053 Purine metabolism Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
M00938 Pyrimidine metabolism Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Occurence in the database

K00525 is associated with 14 different proteins
The 14 proteins are classified into 2 different orthogroup(s)
Orthogroup Locus Start Stop S. Gene Product Organism
0 group_215 FBDBKF_00400 58179 60473 1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S1
1 group_215 EHELCC_01145 248395 250689 -1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S2
2 group_215 NLDBIP_02315 429447 431741 1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S4
3 group_215 LHKJJB_03830 36688 38982 1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S3
4 group_215 HKOGLL_03215 248600 250894 -1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S5
5 group_1614 FBDBKF_10150 119430 121550 1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S1
6 group_1614 EHELCC_04950 311395 313515 1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S2
7 group_1614 NLDBIP_04950 311191 313311 1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S4
8 group_1614 LHKJJB_13680 22067 24187 -1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S3
9 group_1614 HKOGLL_12855 120211 122331 1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella morganii S5
10 group_1614 F4V73_RS00190 49630 51750 -1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Morganella psychrotolerans
11 group_215 F4V73_RS06380 1330639 1332936 1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Morganella psychrotolerans
12 group_1614 PMI_RS02040 482599 484725 -1 nrdE class 1b ribonucleoside-diphosphate reductase subunit alpha Proteus mirabilis HI4320
13 group_215 PMI_RS08510 1855565 1857856 1 nrdA class 1a ribonucleoside-diphosphate reductase subunit alpha Proteus mirabilis HI4320