Pyrimidine metabolism


Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S1 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Pyrimidine metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Pyrimidine metabolism pathway


KO Description #in this genome All occurrences
K00207 dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] 0 0
K00226 dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] 0 0
K00254 dihydroorotate dehydrogenase [EC:1.3.5.2] 1 7
K00524 ribonucleotide reductase, class II [EC:1.17.4.2] 0 0
K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] 2 15
K00526 ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] 2 15
K00527 ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] 0 0
K00560 thymidylate synthase [EC:2.1.1.45] 2 13
K00608 aspartate carbamoyltransferase [EC:2.1.3.2] 0 0
K00609 aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] 1 7
K00610 aspartate carbamoyltransferase regulatory subunit 1 7
K00756 pyrimidine-nucleoside phosphorylase [EC:2.4.2.2] 0 0
K00757 uridine phosphorylase [EC:2.4.2.3] 1 7
K00758 thymidine phosphorylase [EC:2.4.2.4] 1 7
K00761 uracil phosphoribosyltransferase [EC:2.4.2.9] 1 7
K00762 orotate phosphoribosyltransferase [EC:2.4.2.10] 1 7
K00857 thymidine kinase [EC:2.7.1.21] 1 7
K00876 uridine kinase [EC:2.7.1.48] 1 7
K00893 deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113] 0 0
K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] 1 7
K00943 dTMP kinase [EC:2.7.4.9] 1 7
K00945 CMP/dCMP kinase [EC:2.7.4.25] 1 7
K01081 5'-nucleotidase [EC:3.1.3.5] 0 1
K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] 1 7
K01240 uridine nucleosidase [EC:3.2.2.3] 0 0
K01250 pyrimidine-specific ribonucleoside hydrolase [EC:3.2.2.-] 0 0
K01431 beta-ureidopropionase [EC:3.5.1.6] 0 0
K01464 dihydropyrimidinase [EC:3.5.2.2] 1 6
K01465 dihydroorotase [EC:3.5.2.3] 0 0
K01485 cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] 1 7
K01489 cytidine deaminase [EC:3.5.4.5] 1 7
K01493 dCMP deaminase [EC:3.5.4.12] 0 1
K01494 dCTP deaminase [EC:3.5.4.13] 1 7
K01510 apyrase [EC:3.6.1.5] 0 0
K01511 ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] 0 0
K01513 ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] 0 0
K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] 0 0
K01520 dUTP diphosphatase [EC:3.6.1.23] 1 7
K01591 orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] 1 7
K01937 CTP synthase [EC:6.3.4.2] 1 7
K01954 carbamoyl-phosphate synthase [EC:6.3.5.5] 0 0
K01955 carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1 7
K01956 carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] 1 7
K02566 5'-nucleotidase [EC:3.1.3.5] 0 0
K02823 dihydroorotate dehydrogenase electron transfer subunit 0 0
K02825 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] 0 0
K03365 cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] 0 0
K03465 thymidylate synthase (FAD) [EC:2.1.1.148] 0 0
K03787 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] 1 7
K04765 nucleoside triphosphate diphosphatase [EC:3.6.1.9] 1 7
K05961 deoxynucleoside kinase [EC:2.7.1.145] 0 0
K06016 beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] 1 5
K06287 nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] 1 7
K06952 5'-nucleotidase [EC:3.1.3.89] 1 4
K06966 pyrimidine/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-] 1 7
K07023 5'-deoxynucleotidase [EC:3.1.3.89] 0 0
K07043 UTP pyrophosphatase [EC:3.6.1.-] 0 0
K08320 (d)CTP diphosphatase [EC:3.6.1.65] 0 0
K08693 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] 0 0
K08722 5'-deoxynucleotidase [EC:3.1.3.89] 1 7
K08723 pyrimidine 5'-nucleotidase [EC:3.1.3.-] 0 0
K09018 pyrimidine oxygenase [EC:1.14.99.46] 0 0
K09019 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-] 0 0
K09020 ureidoacrylate peracid hydrolase [EC:3.5.1.110] 0 0
K09021 aminoacrylate peracid reductase 0 0
K09023 aminoacrylate hydrolase [EC:3.5.1.-] 0 0
K09024 flavin reductase [EC:1.5.1.-] 0 0
K09769 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] 0 0
K09887 dCTP deaminase (dUMP-forming) [EC:3.5.4.30] 0 0
K09903 uridylate kinase [EC:2.7.4.22] 1 7
K09913 purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] 0 0
K10213 ribosylpyrimidine nucleosidase [EC:3.2.2.8] 0 0
K10807 ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 0 0
K10808 ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 0 0
K11540 carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] 0 0
K11541 carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2] 0 0
K11751 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] 1 7
K12304 soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] 0 0
K12305 ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6] 0 0
K12700 non-specific riboncleoside hydrolase [EC:3.2.2.-] 0 0
K13421 uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] 0 0
K13799 pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25] 0 0
K13800 UMP-CMP kinase [EC:2.7.4.14] 0 0
K13809 UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14] 0 0
K13998 dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] 0 0
K14641 apyrase [EC:3.6.1.5] 0 0
K14642 golgi apyrase [EC:3.6.1.5] 0 0
K15519 deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] 0 0
K16066 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] 1 7
K16328 pseudouridine kinase [EC:2.7.1.83] 1 5
K16329 pseudouridylate synthase [EC:4.2.1.70] 1 5
K16330 pseudouridylate synthase / pseudouridine kinase [EC:4.2.1.70 2.7.1.83] 0 0
K16904 dCTP diphosphatase [EC:3.6.1.12] 0 0
K17722 dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1] 0 0
K17723 dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1] 0 0
K17828 dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] 0 0
K18533 adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6] 0 0
K18931 AMP phosphorylase [EC:2.4.2.57] 0 0
K19794 barbiturase [EC:3.5.2.1] 0 0
K19795 ureidomalonase [EC:3.5.1.95] 0 0
K19796 Straboviridae dCMP hydroxymethylase [EC:2.1.2.8] 0 0
K19797 Straboviridae T-even-induced deoxynucleotide kinase [EC:2.7.4.12] 0 0
K19970 5'-nucleotidase [EC:3.1.3.5] 0 0
K21057 cytidine kinase [EC:2.7.1.213] 0 0
K21636 ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] 1 7
K22026 nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] 0 0
K24242 7-methylguanosine nucleotidase [EC:3.1.3.91] 0 0
K24670 2',3'-cyclic-nucleotide 2'-phosphodiesterase / phosphoenolpyruvate phosphatase [EC:3.1.4.16 3.1.3.60] 0 0
K25434 pyrimidine 5'-nucleotidase [EC:3.1.3.-] 0 0
K25435 putative bifunctional nucleoside triphosphate pyrophosphatase / methyltransferase [EC:3.6.1.- 2.1.1.-] 0 0
K25589 inosine/uridine nucleosidase [EC:3.2.2.2 3.2.2.3] 1 5
K26955 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] 0 0