Purine metabolism

Help to interpret the results


The page contains two contents:
General: this table lists the KO entries and their description specific to this pathway, and provides their frequencies in Morganella morganii S3 and in the whole dataset.
Profile + homologs: the distribution of the Kegg entries of Purine metabolism Kegg pathway is displayed here. Given a Kegg entry and a genome, a red box indicates that one or more loci have been annotated with, while a green box indicates that no locus/loci has(have) been annotated with it, but it/they is/are part of an Orthologous group in which other members have been annotated with that Kegg entry, so it is likely that this copy(ies) also performs this Kegg function.

Check the composition of the Purine metabolism pathway


KO Description #in this genome All occurrences
K00073 ureidoglycolate dehydrogenase (NAD+) [EC:1.1.1.350] 0 1
K00087 xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4] 1 6
K00088 IMP dehydrogenase [EC:1.1.1.205] 1 7
K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] 0 0
K00364 GMP reductase [EC:1.7.1.7] 0 0
K00365 urate oxidase [EC:1.7.3.3] 0 0
K00524 ribonucleotide reductase, class II [EC:1.17.4.2] 0 0
K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] 2 15
K00526 ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] 2 15
K00527 ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] 0 0
K00601 phosphoribosylglycinamide formyltransferase [EC:2.1.2.2] 0 0
K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1 7
K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] 1 7
K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] 1 7
K00764 amidophosphoribosyltransferase [EC:2.4.2.14] 1 7
K00769 xanthine phosphoribosyltransferase [EC:2.4.2.22] 1 7
K00839 (S)-ureidoglycine---glyoxylate transaminase [EC:2.6.1.112] 0 0
K00856 adenosine kinase [EC:2.7.1.20] 0 0
K00860 adenylylsulfate kinase [EC:2.7.1.25] 0 1
K00892 inosine kinase [EC:2.7.1.73] 1 7
K00893 deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113] 0 0
K00904 deoxyguanosine kinase [EC:2.7.1.113] 0 0
K00926 carbamate kinase [EC:2.7.2.2] 1 7
K00939 adenylate kinase [EC:2.7.4.3] 1 7
K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] 1 7
K00942 guanylate kinase [EC:2.7.4.8] 1 7
K00944 nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] 0 0
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1 7
K00951 GTP pyrophosphokinase [EC:2.7.6.5] 0 1
K00955 bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] 0 0
K00956 sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] 0 1
K00957 sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] 0 1
K00958 sulfate adenylyltransferase [EC:2.7.7.4] 0 0
K00988 sulfate adenylyltransferase (ADP) / ATP adenylyltransferase [EC:2.7.7.5 2.7.7.53] 0 0
K01081 5'-nucleotidase [EC:3.1.3.5] 0 1
K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] 1 7
K01120 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] 0 0
K01129 dGTPase [EC:3.1.5.1] 1 8
K01139 GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] 1 7
K01239 purine nucleosidase [EC:3.2.2.1] 0 0
K01241 AMP nucleosidase [EC:3.2.2.4] 0 1
K01427 urease [EC:3.5.1.5] 0 0
K01428 urease subunit alpha [EC:3.5.1.5] 1 7
K01429 urease subunit beta [EC:3.5.1.5] 1 7
K01430 urease subunit gamma [EC:3.5.1.5] 1 7
K01466 allantoinase [EC:3.5.2.5] 0 0
K01477 allantoicase [EC:3.5.3.4] 0 0
K01483 ureidoglycolate lyase [EC:4.3.2.3] 0 0
K01486 adenine deaminase [EC:3.5.4.2] 1 6
K01487 guanine deaminase [EC:3.5.4.3] 1 6
K01488 adenosine deaminase [EC:3.5.4.4] 1 7
K01490 AMP deaminase [EC:3.5.4.6] 0 0
K01492 phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3] 0 0
K01509 adenosinetriphosphatase [EC:3.6.1.-] 0 0
K01510 apyrase [EC:3.6.1.5] 0 0
K01511 ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] 0 0
K01513 ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] 0 0
K01514 exopolyphosphatase [EC:3.6.1.11] 0 0
K01515 ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] 1 7
K01517 manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53] 0 0
K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] 0 0
K01519 XTP/dITP diphosphohydrolase [EC:3.6.1.66] 1 7
K01522 bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29] 0 0
K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] 2 14
K01525 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] 1 7
K01529 inosine/xanthosine triphosphatase [EC:3.6.1.73] 1 7
K01587 phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6] 0 0
K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] 1 7
K01589 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] 1 6
K01756 adenylosuccinate lyase [EC:4.3.2.2] 1 7
K01768 adenylate cyclase [EC:4.6.1.1] 0 0
K01769 guanylate cyclase, other [EC:4.6.1.2] 0 0
K01835 phosphoglucomutase [EC:5.4.2.2] 0 0
K01839 phosphopentomutase [EC:5.4.2.7] 1 7
K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] 1 7
K01933 phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] 1 7
K01939 adenylosuccinate synthase [EC:6.3.4.4] 1 7
K01945 phosphoribosylamine---glycine ligase [EC:6.3.4.13] 1 7
K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 1 7
K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1 7
K02083 allantoate deiminase [EC:3.5.3.9] 0 0
K02566 5'-nucleotidase [EC:3.1.3.5] 0 0
K03651 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] 1 7
K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] 1 6
K03784 purine-nucleoside phosphorylase [EC:2.4.2.1] 2 13
K03787 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] 1 7
K03816 xanthine phosphoribosyltransferase [EC:2.4.2.22] 0 0
K04765 nucleoside triphosphate diphosphatase [EC:3.6.1.9] 1 7
K05810 purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] 1 7
K05851 adenylate cyclase, class 1 [EC:4.6.1.1] 1 7
K05873 adenylate cyclase, class 2 [EC:4.6.1.1] 0 1
K05961 deoxynucleoside kinase [EC:2.7.1.145] 0 0
K06863 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] 0 0
K06928 nucleoside-triphosphatase [EC:3.6.1.15] 0 0
K06952 5'-nucleotidase [EC:3.1.3.89] 1 4
K06966 pyrimidine/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-] 1 7
K07023 5'-deoxynucleotidase [EC:3.1.3.89] 0 0
K07127 5-hydroxyisourate hydrolase [EC:3.5.2.17] 0 1
K07816 GTP pyrophosphokinase [EC:2.7.6.5] 0 0
K08041 adenylate cyclase 1 [EC:4.6.1.1] 0 0
K08042 adenylate cyclase 2 [EC:4.6.1.1] 0 0
K08043 adenylate cyclase 3 [EC:4.6.1.1] 0 0
K08044 adenylate cyclase 4 [EC:4.6.1.1] 0 0
K08045 adenylate cyclase 5 [EC:4.6.1.1] 0 0
K08046 adenylate cyclase 6 [EC:4.6.1.1] 0 0
K08047 adenylate cyclase 7 [EC:4.6.1.1] 0 0
K08048 adenylate cyclase 8 [EC:4.6.1.1] 0 0
K08049 adenylate cyclase 9 [EC:4.6.1.1] 0 0
K08289 phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] 1 7
K08312 ADP compounds hydrolase [EC:3.6.1.-] 1 7
K08693 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5] 0 0
K08718 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35] 0 0
K08722 5'-deoxynucleotidase [EC:3.1.3.89] 1 7
K09769 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] 0 0
K09913 purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] 0 0
K10353 deoxyadenosine kinase [EC:2.7.1.76] 0 0
K10807 ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 0 0
K10808 ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 0 0
K11029 anthrax edema toxin adenylate cyclase [EC:4.6.1.1] 0 0
K11175 phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] 1 7
K11176 IMP cyclohydrolase [EC:3.5.4.10] 0 0
K11177 xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4] 0 0
K11178 xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4] 0 0
K11265 adenylate cyclase 10 [EC:4.6.1.1] 0 0
K11751 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] 1 7
K11787 phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] 0 0
K11788 phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1] 0 0
K11808 phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21] 0 0
K12304 soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] 0 0
K12305 ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6] 0 0
K12318 guanylate cyclase soluble subunit alpha [EC:4.6.1.2] 0 0
K12319 guanylate cyclase soluble subunit beta [EC:4.6.1.2] 0 0
K12320 heat-stable enterotoxin receptor [EC:4.6.1.2] 0 0
K12321 guanylate cyclase 2D/E [EC:4.6.1.2] 0 0
K12322 guanylate cyclase 2F [EC:4.6.1.2] 0 0
K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] 0 0
K12324 atrial natriuretic peptide receptor B [EC:4.6.1.2] 0 0
K13293 cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] 0 0
K13294 cAMP-specific phosphodiesterase [EC:3.1.4.53] 0 0
K13296 cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17] 0 0
K13298 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35] 0 0
K13479 xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4] 1 6
K13480 xanthine dehydrogenase iron-sulfur-binding subunit 0 0
K13481 xanthine dehydrogenase small subunit [EC:1.17.1.4] 0 0
K13482 xanthine dehydrogenase large subunit [EC:1.17.1.4] 0 0
K13483 xanthine dehydrogenase YagT iron-sulfur-binding subunit 0 0
K13484 5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.97] 0 0
K13485 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97] 0 0
K13713 fusion protein PurCD [EC:6.3.2.6 6.3.4.13] 0 0
K13755 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] 0 0
K13756 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35] 0 0
K13757 cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35] 0 0
K13758 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 0 0
K13759 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma 0 0
K13760 retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma 0 0
K13761 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] 0 0
K13762 cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] 0 0
K13763 cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35] 0 0
K13811 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] 0 0
K13987 ADP-ribose diphosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 2.7.7.96] 0 0
K13988 ADP-ribose diphosphatase [EC:3.6.1.13] 0 0
K14048 urease subunit gamma/beta [EC:3.5.1.5] 0 0
K14641 apyrase [EC:3.6.1.5] 0 0
K14642 golgi apyrase [EC:3.6.1.5] 0 0
K14977 (S)-ureidoglycine aminohydrolase [EC:3.5.3.26] 0 0
K15518 deoxyguanosine kinase [EC:2.7.1.113] 0 0
K15519 deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] 0 0
K15778 phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] 0 0
K15779 phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7] 0 0
K15780 bifunctional protein TilS/HprT [EC:6.3.4.19 2.4.2.8] 0 0
K16838 urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:1.7.3.3 4.1.1.97] 0 0
K16839 FAD-dependent urate hydroxylase [EC:1.14.13.113] 0 0
K16840 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97] 0 0
K16841 allantoin racemase [EC:5.1.99.3] 0 0
K16842 allantoinase [EC:3.5.2.5] 0 0
K16855 U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64] 0 0
K16856 ureidoglycolate lyase [EC:4.3.2.3] 0 0
K18151 ureidoglycolate amidohydrolase [EC:3.5.1.116] 0 0
K18283 cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17] 0 0
K18424 ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29] 0 0
K18436 high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53] 0 0
K18437 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53] 0 0
K18438 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35] 0 0
K18445 diadenosine hexaphosphate hydrolase (ATP-forming) [EC:3.6.1.61] 0 0
K18447 ADP-sugar diphosphatase [EC:3.6.1.21] 0 0
K18453 ADP-ribose/FAD diphosphatase [EC:3.6.1.13 3.6.1.18] 0 0
K18532 adenylate kinase [EC:2.7.4.3] 0 0
K18533 adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6] 0 0
K18550 IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-] 0 0
K18931 AMP phosphorylase [EC:2.4.2.57] 0 0
K19021 cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17] 0 0
K19572 adenosine deaminase CECR1 [EC:3.5.4.4] 0 0
K19710 ATP adenylyltransferase [EC:2.7.7.53] 0 0
K19836 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] 0 0
K19964 hydroxyisourate hydrolase [EC:3.5.2.17] 0 0
K19970 5'-nucleotidase [EC:3.1.3.5] 0 0
K20881 GMP/IMP 5'-nucleotidase [EC:3.1.3.-] 0 0
K21053 adenine deaminase [EC:3.5.4.2] 0 0
K21138 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2] 0 0
K21636 ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] 1 7
K22026 nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] 0 0
K22199 phosphopentomutase [EC:5.4.2.7] 0 0
K22600 guanylate cyclase 2G [EC:4.6.1.2] 0 0
K22601 oxamate carbamoyltransferase [EC:2.1.3.5] 0 0
K22602 oxamate amidohydrolase [EC:3.5.1.126] 0 0
K22879 FAD-dependent urate hydroxylase [EC:1.14.13.113] 0 0
K22944 bifunctional hemolysin/adenylate cyclase [EC:4.6.1.1] 0 0
K23264 phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] 0 0
K23265 phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] 0 0
K23269 phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] 0 0
K23270 phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3] 0 0
K24670 2',3'-cyclic-nucleotide 2'-phosphodiesterase / phosphoenolpyruvate phosphatase [EC:3.1.4.16 3.1.3.60] 0 0
K24871 ureidoglycine carbamoyltransferase [EC:2.1.3.16] 0 0
K24972 Vibrio phage 2-amino-2'-deoxyadenylo-succinate synthase [EC:6.3.4.25] 0 0
K25500 Cyanophage dATP/dGTP diphosphohydrolase [EC:3.6.1.-] 0 0
K25589 inosine/uridine nucleosidase [EC:3.2.2.2 3.2.2.3] 1 5
K25641 deoxyguanosine kinase [EC:2.7.1.113] 0 0
K26110 GMP reductase [EC:1.7.1.7] 0 0
K26211 guanosine phosphorylase [EC:2.4.2.15] 0 0
K26212 guanosine phosphorylase [EC:2.4.2.15] 0 0
K26955 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] 0 0
K26956 ADP-ribose/NAD+ diphosphatase [EC:3.6.1.13 3.6.1.22] 0 0